Results 171 to 180 of about 9,897,717 (308)

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Stratégie de recherche du ministère de la Culture 2017-2020 (La) [PDF]

Ce rapport, présentant la stratégie de recherche 2017-2020 du ministère de la Culture, repose sur le travail accompli entre 2014 et 2016 par un comité de pilotage de la recherche Culture.
Ministère de la Culture
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A macrophage-intestinal organoid co-culture model captures balanced epithelial homeostasis and inflammation. [PDF]

Stem Cell Reports
Tonini L, Lee TB, Jang E, Hong S, Choi S, Ahn C.   +5 more
europepmc   +1 more source

Co-culture of embryos and feeder cells [PDF]

Human Reproduction, 1996
openaire   +2 more sources

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Different co-culture approaches to increase metabolites in foods. [PDF]

Food Sci Biotechnol
Uysal GS, Yıldırım HK.
europepmc   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Pigot and Co.'s Royal National and Commercial Directory and Topography of the counties of York, Leicester & Rutland, Lincoln, Northampton, and Nottingham ...to which is added classified directories of the great manufacturing towns of Manchester and Salford ... [1841]

The 1841 Pigot & Co.'s directory of York, Leicester & Rutland, Lincoln, Northampton and Nottingham, and includes ...
Pigot & Co. historical directories;
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Uptake and Transport of Monotropein and Monotropein Esters in a Caco-2/HT29-MTX-E12 Co-Culture Model. [PDF]

Mol Nutr Food Res
Zielinski C, Schmalle V, Lauer LA, Hammerschick T, Rüttler F, Vetter W, Frank J, Jiménez-Aspee F.   +7 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source