Results 181 to 190 of about 9,897,717 (308)

Optimization of a neuron-microglia co-culture model to explore cell-to-cell interaction dynamics. [PDF]

Front Immunol
Vogiatzis S, Severa M, Pietrantoni A, Cairo G, Falco RP, Veroni C, Lanciotti A, Etna MP, Abate DA, Nencioni L, Trevisan M, Coccia EM, Barzon L.   +12 more
europepmc   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Participation in Culture and Satisfaction with Cultural Services in Lithuania, July - August 2023

The purpose of the study: to analyse Lithuanian residents opinion about the accessibility and quality of cultural products and services and to assess the level of the population’s consumption of cultural products and services and participation in the ...
Lithuanian Council for Culture
core   +1 more source

Oxygen Consumption Rate-Defined Phases Couple Metabolism to Matrix Dynamics in Chondrocyte-Mesenchymal Stromal Cell Co-Culture. [PDF]

FASEB J
Ma Z, McEachern L, Lan X, Li DX, Ansari AA, Au I, Barker M, Kunze M, Mulet-Sierra A, Adesida AB.   +9 more
europepmc   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

Correction: Editorial: Innovative organoid co-culture systems for enhanced precision medicine in cancer and beyond. [PDF]

Front Med (Lausanne)
Glaser T, Ecker R, Ritter U.
europepmc   +1 more source

APOBEC3 activity and DNA polymerase‐ε deficiency are associated with distinct IDH1 R132 hotspot mutations

Molecular Oncology, EarlyView.
Isocitrate dehydrogenase 1 (IDH1) mutations are highly recurrent in multiple human cancer types, including cholangiocarcinoma and glioma. IDH1 R132C is the most common IDH1 mutation in cholangiocarcinoma and likely arises from APOBEC3A‐ or APOBEC3B‐mediated deamination.
Kelly E. Butler, Bilal A. Lone, Ecem Unal, A. Rouf Banday   +3 more
wiley   +1 more source

Lotus-fish co-culture reshapes pond microbiota and improves ecological stability relative to fish monoculture. [PDF]

Front Microbiol
Chen S, Miao Y, Yin J, Zhou Z, Yuan Y, Liu Y, Li Y, Zeng L, Wang C, Shen Z, Li W.   +10 more
europepmc   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Protocol for fibrin-based endothelial-cardiomyocyte co-culture in a microfluidic device. [PDF]

STAR Protoc
Spanjersberg TCF, Klaassen A, Wubbolts R, van Dijk CGM, van der Velden J, Veltrop RJA, van der Harst P, Harakalova M, van Steenbeek FG.   +8 more
europepmc   +1 more source