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Efficacy of Formoterol Fumarate Delivered by Metered Dose Inhaler Using Co-Suspension™ Delivery Technology Versus Foradil® Aerolizer® in Moderate-To-Severe COPD: A Randomized, Dose-Ranging Study [PDF]
Background: Co-Suspension™ Delivery Technology offers a novel pharmaceutical platform for inhaled drug therapy. This randomized, double-blind, placebo-controlled, single-dose study (NCT01349868) evaluated the efficacy of a range of doses for formoterol fumarate (FF) delivered using Co-Suspension delivery technology via a pressurized metered dose ...
Sanjay Sethi +2 more
exaly +3 more sources
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2020
Supplemental material, Author_Response_1 for Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD by Wilfried De Backer, Jan De Backer, Ilse Verlinden, Glenn Leemans, Cedric Van Holsbeke, Benjamin Mignot, Martin Jenkins, Dianne ...
Backer, Wilfried De +12 more
openaire +1 more source
Supplemental material, Author_Response_1 for Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD by Wilfried De Backer, Jan De Backer, Ilse Verlinden, Glenn Leemans, Cedric Van Holsbeke, Benjamin Mignot, Martin Jenkins, Dianne ...
Backer, Wilfried De +12 more
openaire +1 more source
2020
Supplemental material, Reviewer_1_v.1 for Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD by Wilfried De Backer, Jan De Backer, Ilse Verlinden, Glenn Leemans, Cedric Van Holsbeke, Benjamin Mignot, Martin Jenkins, Dianne ...
Backer, Wilfried De +12 more
openaire +1 more source
Supplemental material, Reviewer_1_v.1 for Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD by Wilfried De Backer, Jan De Backer, Ilse Verlinden, Glenn Leemans, Cedric Van Holsbeke, Benjamin Mignot, Martin Jenkins, Dianne ...
Backer, Wilfried De +12 more
openaire +1 more source
2020
Supplemental material, Reviewer_2_v.1 for Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD by Wilfried De Backer, Jan De Backer, Ilse Verlinden, Glenn Leemans, Cedric Van Holsbeke, Benjamin Mignot, Martin Jenkins, Dianne ...
Backer, Wilfried De +12 more
openaire +1 more source
Supplemental material, Reviewer_2_v.1 for Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD by Wilfried De Backer, Jan De Backer, Ilse Verlinden, Glenn Leemans, Cedric Van Holsbeke, Benjamin Mignot, Martin Jenkins, Dianne ...
Backer, Wilfried De +12 more
openaire +1 more source
Lancet Respiratory Medicine,the, 2018
Inhaled corticosteroids have been used in patients with chronic obstructive pulmonary disease (COPD), but the potential benefits of their use in triple therapy are not well known. We aimed to compare the efficacy of a triple therapy with corresponding dual therapies in symptomatic patients with moderate to very severe COPD, without a requirement for a ...
Gary T Ferguson +2 more
exaly +3 more sources
Inhaled corticosteroids have been used in patients with chronic obstructive pulmonary disease (COPD), but the potential benefits of their use in triple therapy are not well known. We aimed to compare the efficacy of a triple therapy with corresponding dual therapies in symptomatic patients with moderate to very severe COPD, without a requirement for a ...
Gary T Ferguson +2 more
exaly +3 more sources
Airway pharmacology and treatment, 2018
Objective: To evaluate efficacy and safety of GFF MDI vs placebo MDI and monocomponent MDIs in the Japan subpopulation of the PINNACLE‑4 study (NCT02343458). Methods: In this randomized, double-blind, parallel‑group, 24-week, Phase III study, patients received GFF MDI 14.4/10µg, placebo MDI, glycopyrronium (GP) MDI 14.4µg, or formoterol fumarate ...
Yasuhiro Gon +8 more
openaire +1 more source
Objective: To evaluate efficacy and safety of GFF MDI vs placebo MDI and monocomponent MDIs in the Japan subpopulation of the PINNACLE‑4 study (NCT02343458). Methods: In this randomized, double-blind, parallel‑group, 24-week, Phase III study, patients received GFF MDI 14.4/10µg, placebo MDI, glycopyrronium (GP) MDI 14.4µg, or formoterol fumarate ...
Yasuhiro Gon +8 more
openaire +1 more source
Clinical Problems, 2018
Objective: To assess the relationship of baseline eosinophil (EOS) levels with treatment responses to BGF MDI 320/14.4/10 µg (ICS/LAMA/LABA), glycopyrronium/formoterol [GFF] MDI 14.4/10 µg (LAMA/LABA) and budesonide/formoterol [BFF] MDI 320/10 µg (ICS/LABA).
Leonardo Michele Fabbri +12 more
openaire +1 more source
Objective: To assess the relationship of baseline eosinophil (EOS) levels with treatment responses to BGF MDI 320/14.4/10 µg (ICS/LAMA/LABA), glycopyrronium/formoterol [GFF] MDI 14.4/10 µg (LAMA/LABA) and budesonide/formoterol [BFF] MDI 320/10 µg (ICS/LABA).
Leonardo Michele Fabbri +12 more
openaire +1 more source
Stability analysis of the food delivery robot with suspension damping structure
Heliyon, 2022Shuhai Jiang, Zhongkai Zhou
exaly

