Results 61 to 70 of about 69,822 (254)

A phase III study of triple therapy with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler 320/18/9.6 μg and 160/18/9.6 μg using co-suspension delivery technology in moderate-to-very severe COPD: The ETHOS study protocol [PDF]

open access: yesRespiratory Medicine, 2019
Single inhaler triple therapies providing an inhaled corticosteroid, a long-acting muscarinic antagonist, and a long-acting β2-agonist (ICS/LAMA/LABAs) are an emerging treatment option for chronic obstructive pulmonary disease (COPD). Nevertheless, questions remain regarding the optimal patient population for triple therapy as well as the benefit:risk ...
Klaus F. Rabe   +12 more
openaire   +3 more sources

Microbubbling and microencapsulation by co-axial electrohydrodynamic atomization

open access: yes, 2009
Microbubbles coated with polymers or surfactants have been used in medical imaging for several years as ultrasound contrast agent particles and are now being investigated by researchers as drug and gene delivery vehicles and blood substitutes. Current
Farook, U.
core  

Designing Polymer Nanocomposites for X‐Ray Shielding: Mechanisms, Architectures, and Scalable Processing

open access: yesAdvanced Engineering Materials, EarlyView.
This review highlights advances in lightweight, lead‐free polymer nanocomposites for diagnostic X‐ray shielding. By linking filler chemistry, dispersion, architecture, and photon interaction mechanisms, it establishes structure–performance relationships guiding material design.
Aklilu G. Messele   +2 more
wiley   +1 more source

Riluzole 5 mg/mL oral suspension: for optimized drug delivery in amyotrophic lateral sclerosis

open access: yes, 2016
Ann Margaret Dyer, Alan Smith PharmaSci Consulting Limited, Nottingham, UK Abstract: The aim of the present work is to extensively evaluate the pharmaceutical attributes of currently available riluzole presentations.
Smith A, Dyer AM
core  

Stretching the Printability Metric in Direct‐Ink Writing with Highly Extensible Yield‐Stress Fluids

open access: yesAdvanced Functional Materials, EarlyView.
This study introduces “drawability” as a new metric for assessing printability in direct‐ink writing, focusing on gap‐spanning performance and speed robustness. By designing yield‐stress fluids with high extensibility, we demonstrate that extensional strain‐to‐break significantly enhances printability.
Chaimongkol Saengow   +9 more
wiley   +1 more source

Preparation, characterization and dissolution studies of pharmaceutical co-crystals containing indomethacin

open access: yes, 2013
Purpose: To change the dissolution properties of indomethacin, a non-steroidal anti-inflammatory drug characterized by weak solubility and bioavailability, we propose the preparation of co-crystals where the active pharmaceutical ingredient is ...
DALPIAZ, Alessandro   +2 more
core  

Towards a Requirements Co-engineering Improvement Framework: Supporting Digital Delivery Methods in Complex Infrastructure Projects

open access: yes, 2023
To support the delivery of cyber-physical systems of complex infrastructure assets, different requirements (e.g., physical system requirements, asset information requirements) must be developed and managed properly during the lifecycle of the assets ...
Jupp, JR, Chen, Y
core   +1 more source

Printed Integrated Logic Circuits Based on Chitosan‐Gated Organic Transistors for Future Edible Systems

open access: yesAdvanced Functional Materials, EarlyView.
Edible electronics needs integrated logic circuits for computation and control. This work presents a potentially edible printed chitosan‐gated transistor with a design optimized for integration in circuits. Its implementation in integrated logic gates and circuits operating at low voltage (0.7 V) is demonstrated, as well as the compatibility with an ...
Giulia Coco   +8 more
wiley   +1 more source

Hybrid protein-polymer nanoparticles based on P(NVCL-co-DMAEMA) loaded with cisplatin as a potential anti-cancer agent

open access: yes, 2023
Responsive polymers are a promising class of materials for a variety of applications, especially for the construction of biomedical devices such as novel drug delivery systems.
Mathieu-Gaedke, Maria   +6 more
core   +1 more source

Composites of Shellac and Silver Nanowires as Flexible, Biobased, and Corrosion‐Resistant Transparent Conductive Electrodes

open access: yesAdvanced Functional Materials, EarlyView.
Shellac, a centuries‐old natural resin, is reimagined as a green material for flexible electronics. When combined with silver nanowires, shellac films deliver transparency, conductivity, and stability against humidity. These results position shellac as a sustainable alternative to synthetic polymers for transparent conductors in next‐generation ...
Rahaf Nafez Hussein   +4 more
wiley   +1 more source

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