Results 11 to 20 of about 24,818 (181)

The cobalamin-binding protein in zebrafish is an intermediate between the three cobalamin-binding proteins in human.

PLoS ONE, 2012
In humans, three soluble extracellular cobalamin-binding proteins; transcobalamin (TC), intrinsic factor (IF), and haptocorrin (HC), are involved in the uptake and transport of cobalamin.
Eva Greibe, Sergey Fedosov, Ebba Nexo
doaj   +1 more source

In Dogs With Chronic Enteropathies, Can Oral B12 Tablets Be Used to Treat Hypocobalaminaemia?

Veterinary Evidence, 2019
PICO question In dogs with chronic enteropathy does treatment with oral cobalamin compared to parenteral cobalamin provide serum cobalamin levels greater than 270 ng/L?
Avril McGinn
doaj   +1 more source

Cobalamin Scarcity Modifies Carbon Allocation and Impairs DMSP Production Through Methionine Metabolism in the Haptophyte Microalgae Tisochrysis lutea

Frontiers in Marine Science, 2020
Cobalamin (vitamin B12) is a cobalt-containing enzymatic cofactor involved in methionine synthesis. Provided only by select bacteria and archaea in marine systems, this vitamin is known to limit primary production in different oceanic areas ...
Charlotte Nef, Céline Henry, Élodie Nicolau, Jean-Baptiste Bérard, Fabienne Hervé, Amandine M. N. Caruana, Raymond Kaas, Francis Mairet, Matthieu Garnier   +8 more
doaj   +1 more source

Vitamin B12 in Cats: Nutrition, Metabolism, and Disease

Animals, 2023
Cobalamin is a water-soluble molecule that has an important role in cellular metabolism, especially in DNA synthesis, methylation, and mitochondrial metabolism. Cobalamin is bound by intrinsic factor (IF) and absorbed in the ileal tract.
Gerardo Siani, Beatrice Mercaldo, Maria Chiara Alterisio, Antonio Di Loria   +3 more
doaj   +1 more source

Effect of Administration Route on the Pharmacokinetics of Cobalamin in Elderly Patients: A Randomized Controlled Trial

Current Therapeutic Research, 2014
Background: The gold standard for cobalamin deficiency treatment is administration of cobalamin by intramuscular injection. The injection is painful and inconvenient, particularly for elderly persons.
Monique P.H. Tillemans, PharmD, Eline M.V.J. Donders, MD, Sjoerd L. Verweij, PharmD, Ruud T.M. Van der Hoeven, PharmD, Kees J. Kalisvaart, MD, PhD   +4 more
doaj   +1 more source

Serum cobalamin and methylmalonic acid concentrations in juvenile dogs with parvoviral enteritis or other acute enteropathies

Journal of Veterinary Internal Medicine, 2023
Background Low serum cobalamin concentrations have been associated with ileal malabsorption in dogs with chronic enteropathy. Increased serum methylmalonic acid (MMA) concentrations indicate cobalamin deficiency on a cellular level.
Michael Hung, Justin Heinz, Jӧrg M. Steiner, Jan Suchodolski, Jonathan Lidbury   +4 more
doaj   +1 more source

An Unusual Case of Severe Vitamin B12 Deficiency With Early Erythroblasts on Peripheral Blood Film. [PDF]

EJHaem
eJHaem, Volume 6, Issue 6, December 2025.
Muscat J, Gatt A.
europepmc   +2 more sources

Extracellular loops of BtuB facilitate transport of vitamin B12 through the outer membrane of E. coli.

PLoS Computational Biology, 2020
Vitamin B12 (or cobalamin) is an enzymatic cofactor essential both for mammals and bacteria. However, cobalamin can be synthesized only by few microorganisms so most bacteria need to take it up from the environment through the TonB-dependent transport ...
Tomasz Pieńko, Joanna Trylska
doaj   +1 more source

Effect of oral or injectable supplementation with cobalamin in dogs with hypocobalaminemia caused by chronic enteropathy or exocrine pancreatic insufficiency

Journal of Veterinary Internal Medicine, 2022
Background Recent studies have shown similar efficacy of oral supplementation of cobalamin compared to injectable supplementation in dogs, but few prospective, randomized studies have been published.
Chee‐Hoon Chang, Jonathan A. Lidbury, Jan S. Suchodolski, Joerg M. Steiner   +3 more
doaj   +1 more source

Correction to "Characteristics, Nutritional Recommendations, and Medical Interventions of 58 Dogs With Protein-Losing Enteropathy Presenting to a Veterinary Nutrition Service". [PDF]

J Vet Intern Med
Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
europepmc   +2 more sources