Results 11 to 20 of about 39,443 (213)

Rapid healing of a patient with dramatic subacute combined degeneration of spinal cord: a case report [PDF]

, 2017
Background: Prevalence of cobalamin deficiency is high especially in older patients and an immediate therapy start is necessary to prevent irreversible neurological damages. Unfortunately, the diagnosis of cobalamin deficiency is difficult and at present,
Roessler, Florian C., Wolff, Stephanie
core   +1 more source

The cobalamin-binding protein in zebrafish is an intermediate between the three cobalamin-binding proteins in human.

PLoS ONE, 2012
In humans, three soluble extracellular cobalamin-binding proteins; transcobalamin (TC), intrinsic factor (IF), and haptocorrin (HC), are involved in the uptake and transport of cobalamin.
Eva Greibe, Sergey Fedosov, Ebba Nexo
doaj   +1 more source

Gene identification for the cblD defect of vitamin B12 metabolism [PDF]

, 2008
Background Vitamin B12 (cobalamin) is an essential cofactor in several metabolic pathways. Intracellular conversion of cobalamin to its two coenzymes, adenosylcobalamin in mitochondria and methylcobalamin in the cytoplasm, is necessary for the ...
Baumgartner, M R, Coelho, D, Fowler, B, Lerner-Ellis, J P, Newbold, R F, Rosenblatt, D S, Stucki, M, Suormala, T   +7 more
core   +1 more source

In Dogs With Chronic Enteropathies, Can Oral B12 Tablets Be Used to Treat Hypocobalaminaemia?

Veterinary Evidence, 2019
PICO question In dogs with chronic enteropathy does treatment with oral cobalamin compared to parenteral cobalamin provide serum cobalamin levels greater than 270 ng/L?
Avril McGinn
doaj   +1 more source

Cobalamin Scarcity Modifies Carbon Allocation and Impairs DMSP Production Through Methionine Metabolism in the Haptophyte Microalgae Tisochrysis lutea

Frontiers in Marine Science, 2020
Cobalamin (vitamin B12) is a cobalt-containing enzymatic cofactor involved in methionine synthesis. Provided only by select bacteria and archaea in marine systems, this vitamin is known to limit primary production in different oceanic areas ...
Charlotte Nef, Céline Henry, Élodie Nicolau, Jean-Baptiste Bérard, Fabienne Hervé, Amandine M. N. Caruana, Raymond Kaas, Francis Mairet, Matthieu Garnier   +8 more
doaj   +1 more source

Novel pathway for corrinoid compounds production in lactobacillus [PDF]

, 2018
Vitamin B12 or cobalamin is an essential metabolite for humans, which makes it an interesting compound for many research groups that focus in different producer-strains synthesis pathways.
Font, Graciela Maria, Saavedra, Maria Lucila, Taranto, Maria Pia, Torres, Andrea Carolina, Vannini, María Verónica   +4 more
core   +2 more sources

Vitamin B12 in Cats: Nutrition, Metabolism, and Disease

Animals, 2023
Cobalamin is a water-soluble molecule that has an important role in cellular metabolism, especially in DNA synthesis, methylation, and mitochondrial metabolism. Cobalamin is bound by intrinsic factor (IF) and absorbed in the ileal tract.
Gerardo Siani, Beatrice Mercaldo, Maria Chiara Alterisio, Antonio Di Loria   +3 more
doaj   +1 more source

Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme. [PDF]

, 2019
Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are produced exclusively by bacteria and archaea but used in all domains of life.
Mok, Kenny, Park, Jong, Quanstrom, Kathryn, Sokolovskaya, Olga, Taga, Michi, Tran, Jennifer   +5 more
core   +1 more source

Effect of Administration Route on the Pharmacokinetics of Cobalamin in Elderly Patients: A Randomized Controlled Trial

Current Therapeutic Research, 2014
Background: The gold standard for cobalamin deficiency treatment is administration of cobalamin by intramuscular injection. The injection is painful and inconvenient, particularly for elderly persons.
Monique P.H. Tillemans, PharmD, Eline M.V.J. Donders, MD, Sjoerd L. Verweij, PharmD, Ruud T.M. Van der Hoeven, PharmD, Kees J. Kalisvaart, MD, PhD   +4 more
doaj   +1 more source

Serum cobalamin and methylmalonic acid concentrations in juvenile dogs with parvoviral enteritis or other acute enteropathies

Journal of Veterinary Internal Medicine, 2023
Background Low serum cobalamin concentrations have been associated with ileal malabsorption in dogs with chronic enteropathy. Increased serum methylmalonic acid (MMA) concentrations indicate cobalamin deficiency on a cellular level.
Michael Hung, Justin Heinz, Jӧrg M. Steiner, Jan Suchodolski, Jonathan Lidbury   +4 more
doaj   +1 more source