Skin-associated Corynebacterium amycolatum shares cobamides [PDF]
mSphereThe underlying interactions that occur to maintain skin microbiome composition, function, and overall skin health are largely unknown. Often, these types of interactions are mediated by microbial metabolites.
M. H. Swaney +4 more
doaj +5 more sources
Acinetobacter baumannii Catabolizes Ethanolamine in the Absence of a Metabolosome and Converts Cobinamide into Adenosylated Cobamides [PDF]
mBio, 2022 Acinetobacter baumannii is an opportunistic pathogen typically associated with hospital-acquired infections. Our understanding of the metabolism and physiology of A. baumannii is limited. Here, we report that A.
Elizabeth A. Villa +1 more
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Isolation of cobamides from Methanothrix soehngenii: 5-methylbenzimidazole as the ?-ligand of the predominant cobamide [PDF]
Archives of Microbiology, 1988 Methanothrix soehngenii was found to contain five different cobamides when grown on vitamin B12 supplemented as well as vitamin B12 free media. In both cases, it was shown by HPLC-chromatography and UV/VIS spectroscopy, that α-5-methylbenzimidazolyl-β-cyanocobamide was the predominant cobamide, accounting for 27% and 23%, respectively, of the total ...
Hans-Peter Kohler
exaly +4 more sources
Vitamin B12 as a source of variability in isotope effects for chloroform biotransformation by Dehalobacter [PDF]
MicrobiologyOpenCarbon and chlorine isotope effects for biotransformation of chloroform by different microbes show significant variability. Reductive dehalogenases (RDase) enzymes contain different cobamides, affecting substrate preferences, growth yields, and ...
Elizabeth Phillips +8 more
doaj +3 more sources
Nutrient encryption and the diversity of cobamides, siderophores, and glycans. [PDF]
Trends Microbiol, 2023 Encryption makes information available only to those with the decoding key. We propose that microbes, living in a chemical environment, encrypt nutrients, thereby making them available only to those with the decoding enzymes, such as their kin. Examples of encrypted nutrients include cobamides, which are expensive to make and valuable for microbial ...
Taga ME, Ludington WB.
europepmc +4 more sources
Cobamide excretion allows Salmonella to transition from its anaerobic to aerobic lifestyle [PDF]
Microbiology SpectrumCobamides (Cbas) are structurally complex biomolecules used by cells of all domains of life. However, de novo Cba biosynthesis occurs only in some bacteria and archaea.
Lahiru Malalasekara +1 more
doaj +3 more sources
Cofactor Selectivity in Methylmalonyl Coenzyme A Mutase, a Model Cobamide-Dependent Enzyme [PDF]
mBio, 2019 Cobamides, a uniquely diverse family of enzyme cofactors related to vitamin B12, are produced exclusively by bacteria and archaea but used in all domains of life.
Olga M. Sokolovskaya +5 more
doaj +2 more sources
Cofactor binding interactions with reductive dehalogenase shape cobamide utilization in organohalide-respiring bacteria [PDF]
Communications BiologySelective utilization of certain cobamides, the vitamin B12-family enzyme cofactors, is a common physiological trait in organohalide respiration, an essential biogeochemical process relevant to global halogen cycling and the bioremediation of chlorinated
Huijuan Jin +10 more
doaj +2 more sources
Identification of a Novel Cobamide Remodeling Enzyme in the Beneficial Human Gut Bacterium
mBio, 2020 The beneficial human gut bacterium Akkermansia muciniphila provides metabolites to other members of the gut microbiota by breaking down host mucin, but most of its other metabolic functions have not been investigated. A.
Kenny C. Mok +6 more
doaj +2 more sources
A bioassay for the detection of benzimidazoles reveals their presence in a range of environmental samples [PDF]
Frontiers in Microbiology, 2014 Cobamides are a family of enzyme cofactors that include vitamin B12 (cobalamin) and are produced solely by prokaryotes. Structural variability in the lower axial ligand has been observed in cobamides produced by diverse organisms. Of the three classes of
Terence S Crofts +3 more
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