Results 1 to 10 of about 7,362 (203)

Current Insights in the Mechanisms of Cobra Venom Cytotoxins and Their Complexes in Inducing Toxicity: Implications in Antivenom Therapy [PDF]

Toxins, 2022
Cytotoxins (CTXs), an essential class of the non-enzymatic three-finger toxin family, are ubiquitously present in cobra venoms. These low-molecular-mass toxins, contributing to about 40 to 60% of the cobra venom proteome, play a significant role in cobra
Bhargab Kalita, Yuri N Utkin, Ashis K Mukherjee   +2 more
exaly   +5 more sources

miRNAs derived from cobra venom exosomes contribute to the cobra envenomation [PDF]

Journal of Nanobiotechnology, 2023
Currently, there is an increasing amount of evidence indicating that exosomes and the miRNAs they contain are crucial players in various biological processes. However, the role of exosomes and miRNAs in snake venom during the envenomation process remains
Tianci Liao, Mailin Gan, Yanhao Qiu, Yuhang Lei, Qiuyang Chen, Xingyu Wang, Yiting Yang, Lei Chen, Ye Zhao, Lili Niu, Yan Wang, Shunhua Zhang, Li Zhu, Linyuan Shen   +13 more
doaj   +3 more sources

Influential Factors of Local Tissue Necrosis after Taiwan Cobra Bites: A Secondary Analysis of the Clinical Significance of Venom Detection in Patients of Cobra Snakebites

Toxins, 2021
Local tissue swelling, inflammation, and wound necrosis are observed in Taiwan cobra bites. Knowledge of the factors influencing local tissue necrosis after cobra bites might improve the cobra bite treatment strategy.
Chih-Chuan Lin, Chung－Hsien Chaou, Chih-Chuan Lin   +2 more
exaly   +4 more sources

Ophthalmia Secondary to Cobra Venom Spitting in the Volta Region, Ghana: A Case Report [PDF]

Case Reports in Ophthalmology, 2017
Purpose: To report the first case of ophthalmia due to contact with cobra venom in the Volta Region, Ghana. Methods: An ointment containing vitamin A was applied to treat the patient’s unilateral defects in the corneal epithelium and the consequent ...
Maria Andrea Lanzetta, Mihaela Cirtita, Evelyn Aziebu, Momodou Cham, Paolo Lanzetta   +4 more
doaj   +3 more sources

Recombinant antibodies against Iranian cobra venom as a new emerging therapy by phage display technology [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Background: The production of antivenom from immunized animals is an established treatment for snakebites; however, antibody phage display technology may have the capacity to delivery results more quickly and with a better match to local need.
Ali Nazari, Maedeh Samianifard, Hadi Rabie, Abbas Zare Mirakabadi   +3 more
doaj   +3 more sources

Interaction of Human Lymphocyte Scavenger Receptors CD5 and CD6 with Toxins from Naja haje, Androctonus australis and Apis mellifera Venoms [PDF]

Biomolecules
Animal venoms induce systemic inflammatory response syndrome through their interaction, inter alia, with pattern recognition receptors (PRRs) of the innate immune system.
Dalila Khemili, Laura Carrillo-Serradell, Violeta Planells-Romeo, Lucía Aragón-Serrano, Selma Djilani, Djelila Hammoudi-Triki, Khedidja Zerouti, Abdenacer Mouffok, Francisco Lozano, María Velasco-de-Andrés   +9 more
doaj   +2 more sources

Atrase A, a P-III class metalloproteinase purified from cobra venom, exhibits potent anticoagulant activity by inhibiting coagulation pathway and activating the fibrinolytic system [PDF]

Heliyon
Snake venoms, comprising a complex array of protein-rich components, an important part of which are snake venom metalloproteinases (SVMPs). These SVMPs, which are predominantly isolated from viperid venoms, are integral to the pathology of snakebites ...
Xin-Jie Zhong, Cai-E Wang, Ya-Nan Li, Qi-Yun Zhang, Qian-Yun Sun   +4 more
doaj   +2 more sources

Evaluation of Nanodiamond-in-Oil Emulsion with Snake Venom to Enhance Potent Antibody Induction in Mice and Rabbits [PDF]

Nanomaterials
Nanodiamonds (NDs) are an innovative material in biomedical applications based on their excellent biocompatibility, nanoscale dimensions, and high surface area.
Min-Han Lin, Long-Jyun Su, Hsin-Hung Lin, Liang-Yu Chen, Asmaul Husna, Wang-Chou Sung   +5 more
doaj   +2 more sources

Effects of Cape Cobra (Naja nivea) Venom and Its Isolated Protein on the Modulation of Platelet Activation [PDF]

Toxins
The Cape cobra (Naja nivea), one of Africa’s most lethal snakes, can cause rapid, life-threatening paralysis. However, the impact of this venom on platelet function and blood coagulation remains poorly understood. To address this gap, we investigated the
Mahtab Khatibi, José R. Almeida, Ashifa Al Juwaiser, Soheil Gilabadi, Ketan Patel, Sakthivel Vaiyapuri   +5 more
doaj   +2 more sources

Curcumin alleviates pain and improves cognitive impairment in a rat model of cobra venom-induced trigeminal neuralgia [PDF]

Journal of Pain Research, 2018
Li Zhang,1 Xinli Ding,2 Zhe Wu,3 Min Wang,1 Ming Tian1 1Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, 2Department of Rehabilitation Medicine, Shandong Provincial Hospital Affiliated to Shandong ...
Zhang L, Ding X, Wu Z, Wang M, Tian M
doaj   +2 more sources