Results 21 to 30 of about 7,362 (203)

Ocular complications of spitting cobra venom. [PDF]

Indian J Ophthalmol, 2020
Jalink MB.
europepmc   +4 more sources

Toxicological and pathophysiological alterations accompanied treating cancer with the Egyptian cobra (Naja haje) crude venom on mice [PDF]

Egyptian Journal of Cancer and Biomedical Research, 2022
Cancer is one of the human mortality leading causes. While there are many tumor treatment modalities, but chemotherapy remains the most effective treatment, although its severe side effects and developed resistance.
Hosni Neweigy, Mona Gouida, Mohamed Salem, Mohamed El Naggar   +3 more
doaj   +1 more source

Venom Variation of Neonate and Adult Chinese Cobras in Captivity Concerning Their Foraging Strategies

Toxins, 2022
The venom and transcriptome profile of the captive Chinese cobra (Naja atra) is not characterized  until now. Here, LC-MS/MS and illumine technology were used to unveil the venom and trascriptome of neonates and adults N. atra specimens.
Xuekui Nie, Qianzi Chen, Chen Wang, Wangxiang Huang, Ren Lai, Qiumin Lu, Qiyi He, Xiaodong Yu   +7 more
doaj   +1 more source

King Cobra and snakebite envenomation: on the natural history, human-snake relationship and medical importance of Ophiophagus hannah

Journal of Venomous Animals and Toxins including Tropical Diseases, 2022
King Cobra (Ophiophagus hannah) has a significant place in many cultures, and is a medically important venomous snake in the world. Envenomation by this snake is highly lethal, manifested mainly by neurotoxicity and local tissue damage. King Cobra may be
Choo Hock Tan, Aymeric Bourges, Kae Yi Tan   +2 more
doaj   +1 more source

The Effect of Australian and Asian Commercial Antivenoms in Reversing the Post-Synaptic Neurotoxicity of O. hannah, N. naja and N. kaouthia Venoms In Vitro

Toxins, 2022
Despite antivenoms being the only established specific treatment for neuromuscular paralysis arising from snake envenoming, their ability to reverse the post-synaptic neurotoxicity in snake envenoming is poorly understood.
Tam M. Huynh, Wayne C. Hodgson, Geoffrey K. Isbister, Anjana Silva   +3 more
doaj   +1 more source

Pathogenesis of local necrosis induced by Naja atra venom: Assessment of the neutralization ability of Taiwanese freeze-dried neurotoxic antivenom in animal models.

PLoS Neglected Tropical Diseases, 2020
Naja atra envenomation is one of the most significant clinical snakebite concerns in Taiwan. Taiwanese freeze-dried neurotoxic antivenom (FNAV) is currently used clinically for the treatment of cobra snakebite, and has been shown to limit the mortality ...
Chien-Chun Liu, Yu-Shao Chou, Chun-Yu Chen, Kuei-Lin Liu, Guo-Jen Huang, Jau-Song Yu, Cho-Ju Wu, Geng-Wang Liaw, Cheng-Hsien Hsieh, Chun-Kuei Chen   +9 more
doaj   +1 more source

Assessing the Efficacy of Monovalent and Commercialized Antivenoms for Neutralizing Moroccan Cobra Naja haje Venom: A Comparative Study

Tropical Medicine and Infectious Disease, 2023
In Morocco, eight species of venomous snakes belonging to the Viperidae and Elapidae families are responsible for severe envenomation cases. The species from the Elapidae family is only represented by the medically relevant cobra Naja haje, which is ...
Soukaina Khourcha, Ines Hilal, Iatimad Elbejjaj, Mehdi Karkouri, Amal Safi, Abdelaziz Hmyene, Naoual Oukkache   +6 more
doaj   +1 more source

Development of a Broad-Spectrum Antiserum against Cobra Venoms Using Recombinant Three-Finger Toxins

Toxins, 2021
Three-finger toxins (3FTXs) are the most clinically relevant components in cobra (genus Naja) venoms. Administration of the antivenom is the recommended treatment for the snakebite envenomings, while the efficacy to cross-neutralize the different cobra ...
Bing-Sin Liu, Bo-Rong Jiang, Kai-Chieh Hu, Chien-Hsin Liu, Wen-Chin Hsieh, Min-Han Lin, Wang-Chou Sung   +6 more
doaj   +1 more source

A Rapid and International Applicable Diagnostic Device for Cobra (Genus Naja) Snakebites

Toxins, 2020
Cobra snakes (genus Naja) are some of the most dangerous snake species in Asia and Africa, as their bites cause severe life-threatening respiratory failure and local tissue destruction, especially in the case of late diagnosis. The differential diagnosis
Jing-Hua Lin, Wang-Chou Sung, Jiunn-Wang Liao, Dong-Zong Hung   +3 more
doaj   +1 more source

Physiological constraints dictate toxin spatial heterogeneity in snake venom glands

BMC Biology, 2022
Background Venoms are ecological innovations that have evolved numerous times, on each occasion accompanied by the co-evolution of specialised morphological and behavioural characters for venom production and delivery.
Taline D. Kazandjian, Brett R. Hamilton, Samuel D. Robinson, Steven R. Hall, Keirah E. Bartlett, Paul Rowley, Mark C. Wilkinson, Nicholas R. Casewell, Eivind A. B. Undheim   +8 more
doaj   +1 more source