Results 21 to 30 of about 78,027 (186)

A Neurotoxic Snake Venom without Phospholipase A₂: Proteomics and Cross-Neutralization of the Venom from Senegalese Cobra, Naja senegalensis (Subgenus: Uraeus)

Toxins, 2021
The Senegalese cobra, Naja senegalensis, is a non-spitting cobra species newly erected from the Naja haje complex. Naja senegalensis causes neurotoxic envenomation in Western Africa but its venom properties remain underexplored.
Kin Ying Wong, Kae Yi Tan, Nget Hong Tan, Choo Hock Tan   +3 more
doaj   +1 more source

Influential Factors of Local Tissue Necrosis after Taiwan Cobra Bites: A Secondary Analysis of the Clinical Significance of Venom Detection in Patients of Cobra Snakebites

Toxins, 2021
Local tissue swelling, inflammation, and wound necrosis are observed in Taiwan cobra bites. Knowledge of the factors influencing local tissue necrosis after cobra bites might improve the cobra bite treatment strategy.
Chih-Chuan Lin, Chung-Hsien Chaou, Shi-Ying Gao   +2 more
doaj   +1 more source

The Effect of Australian and Asian Commercial Antivenoms in Reversing the Post-Synaptic Neurotoxicity of O. hannah, N. naja and N. kaouthia Venoms In Vitro

Toxins, 2022
Despite antivenoms being the only established specific treatment for neuromuscular paralysis arising from snake envenoming, their ability to reverse the post-synaptic neurotoxicity in snake envenoming is poorly understood.
Tam M. Huynh, Wayne C. Hodgson, Geoffrey K. Isbister, Anjana Silva   +3 more
doaj   +1 more source

The protective effects of Mucuna pruriens seed extract against histopathological changes induced by Malayan cobra (Naja sputatrix) venom in rats [PDF]

, 2009
Seed of Mucuna pruriens (Velvet beans) has been prescribed by traditional medicine practitioners in Nigeria as a prophylactic oral antisnake remedy. In the present studies, we investigated the protective effects of M.
Fung, S.Y., Aguiyi, J.C., Sim, S.M., Tan, N.H., Liew, S.H.   +4 more
core   +3 more sources

Pathogenesis of local necrosis induced by Naja atra venom: Assessment of the neutralization ability of Taiwanese freeze-dried neurotoxic antivenom in animal models.

PLoS Neglected Tropical Diseases, 2020
Naja atra envenomation is one of the most significant clinical snakebite concerns in Taiwan. Taiwanese freeze-dried neurotoxic antivenom (FNAV) is currently used clinically for the treatment of cobra snakebite, and has been shown to limit the mortality ...
Chien-Chun Liu, Yu-Shao Chou, Chun-Yu Chen, Kuei-Lin Liu, Guo-Jen Huang, Jau-Song Yu, Cho-Ju Wu, Geng-Wang Liaw, Cheng-Hsien Hsieh, Chun-Kuei Chen   +9 more
doaj   +1 more source

Assessing the Efficacy of Monovalent and Commercialized Antivenoms for Neutralizing Moroccan Cobra Naja haje Venom: A Comparative Study

Tropical Medicine and Infectious Disease, 2023
In Morocco, eight species of venomous snakes belonging to the Viperidae and Elapidae families are responsible for severe envenomation cases. The species from the Elapidae family is only represented by the medically relevant cobra Naja haje, which is ...
Soukaina Khourcha, Ines Hilal, Iatimad Elbejjaj, Mehdi Karkouri, Amal Safi, Abdelaziz Hmyene, Naoual Oukkache   +6 more
doaj   +1 more source

Pharmacological aspects of Vipera xantina palestinae venom [PDF]

, 2011
In Israel, Vipera xantina palestinae (V.x.p.) is the most common venomous snake, accounting for several hundred cases of envenomation in humans and domestic animals every year, with a mortality rate of 0.5 to 2%.
Katzhendler, Jeoshua, Franziska T. Arlinghaus, Jeoshua Katzhendler, Cezary Marcinkiewicz, Philip Lazarovici, Johannes A. Eble, Lazarovici, Philip, Momic, Tatjana, Eble, Johannes A., Hadar Arien-Zakay, Marcinkiewicz, Cezary, Tatjana Momic, Arien-Zakay, Hadar, Arlinghaus, Franziska Therese, Arlinghaus, Franziska T.   +14 more
core   +1 more source

Development of a Broad-Spectrum Antiserum against Cobra Venoms Using Recombinant Three-Finger Toxins

Toxins, 2021
Three-finger toxins (3FTXs) are the most clinically relevant components in cobra (genus Naja) venoms. Administration of the antivenom is the recommended treatment for the snakebite envenomings, while the efficacy to cross-neutralize the different cobra ...
Bing-Sin Liu, Bo-Rong Jiang, Kai-Chieh Hu, Chien-Hsin Liu, Wen-Chin Hsieh, Min-Han Lin, Wang-Chou Sung   +6 more
doaj   +1 more source

A Rapid and International Applicable Diagnostic Device for Cobra (Genus Naja) Snakebites

Toxins, 2020
Cobra snakes (genus Naja) are some of the most dangerous snake species in Asia and Africa, as their bites cause severe life-threatening respiratory failure and local tissue destruction, especially in the case of late diagnosis. The differential diagnosis
Jing-Hua Lin, Wang-Chou Sung, Jiunn-Wang Liao, Dong-Zong Hung   +3 more
doaj   +1 more source

Physiological constraints dictate toxin spatial heterogeneity in snake venom glands

BMC Biology, 2022
Background Venoms are ecological innovations that have evolved numerous times, on each occasion accompanied by the co-evolution of specialised morphological and behavioural characters for venom production and delivery.
Taline D. Kazandjian, Brett R. Hamilton, Samuel D. Robinson, Steven R. Hall, Keirah E. Bartlett, Paul Rowley, Mark C. Wilkinson, Nicholas R. Casewell, Eivind A. B. Undheim   +8 more
doaj   +1 more source