Results 161 to 170 of about 13,049 (217)
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Cobra Bite Following Immunization Against Cobra Venom
JAMA: The Journal of the American Medical Association, 1965THE INDIAN COBRA ( Naja naja ) is considered by most authorities to be one of the most deadly snakes in the world. In India, where the annual mortality from snakebite may reach 25,000 to 30,000, the bite of the cobra is considered one of the prime offenders. Ahuja and Singh 1 and Puranananda 2 have reviewed the symptomatology of cobra bite.
E D, CANAN, H H, FLOWERS
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Cardiovascular Effects of Cobra Venom
JAMA: The Journal of the American Medical Association, 1963COBRA VENOM produces profound cardiovascular changes, and envenomed animals maintained by artificial respiration die of circulatory collapse. Evidence to date suggests that both heart and peripheral vessels are affected. In experiments reported herein, cardiac and peripheral vascular changes produced by venom of Naja naja were studied.
K, BHANGANADA, J F, PERRY
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Cobra venom keratoconjunctivitis
BMJ Case ReportsWe present a case of cobra venom keratoconjunctivitis, an ocular injury caused by a snake’s defensive mechanism of spitting venom into a predator’s eyes. A male in his 50s reported to the outpatient department of a regional hospital in Songea, Tanzania, with 24 hours of eye pain, photophobia and decreased vision after being sprayed in the face by a ...
Rita Sofia Glazer +3 more
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Cobra venom acetylcholinesterase—II. Substrate specifity
Comparative Biochemistry and Physiology Part C: Comparative Pharmacology, 1979Abstract 1. The apparent Michaelis constants, K m (app), catalytical rate constants, k cat , and bimolecular rate constants, k , for the reaction of cobra venom acetylcholinesterase with 6 cationic substrates and phenyl acetate in 0.15 M KCl at 25°C and pH 7.5 have been determined.
T, Kesvatera, M, Ustav, A, Aaviksaar
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Fractionation of egyptian cobra venom
Toxicon, 1974Abstract Five toxic fractions were isolated from Egyptian Naja haje venom by filtration using Sephadex G-75. Applying immunodiffusion techniques, fractions four and five were found to contain γ(cardiotoxic)- and α(neurotoxic)-like antigenic activity, respectively. The maximum phospholipase A activity was recorded in fraction three.
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Journal of Pharmaceutical Sciences, 1977
Two moieties occurring in crude Naja naja cobra venom were found to possess anticomplement activity. Both materials possessed similar molecular weights and specific activities but dissimilar elution profiles upon ion-exchange chromatography. The anticomplement activities of these materials were maintained upon digestion with neuraminidase, and their ...
B J, Johnson, U N, Kucich
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Two moieties occurring in crude Naja naja cobra venom were found to possess anticomplement activity. Both materials possessed similar molecular weights and specific activities but dissimilar elution profiles upon ion-exchange chromatography. The anticomplement activities of these materials were maintained upon digestion with neuraminidase, and their ...
B J, Johnson, U N, Kucich
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Effect of Cobra Venom on Leucocytes
American Journal of Physiology-Legacy Content, 1958Intermittent injections of sublethal doses of the venom of Naja haje of Egypt caused temporary leucopenia followed by leucocytosis in guinea-pigs and rabbits. There was always a rise in the percentage of neutrophil leucocytes and a corresponding drop in the percentage of lymphocytes.
F, KHALIL, I, ABOU-EL-NAGA, Z M, RIAD
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Inactivation of thromboplastin by cobra venom
Biochimica et Biophysica Acta, 1950This paper reports some studies on the anticoagulant effect of cobra venom on chicken blood. It was found that the venom has a strong inactivating or destructive action on thromboplastin, and it is concluded that the destruction of thromboplastin is an essential factor in the anticoagulant effect of cobra venom.
I, KRUSE, H, DAM
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Antiproliferative Activity of Cobra Venom Cytotoxins
Current Topics in Medicinal Chemistry, 2015Cytotoxins (or cardiotoxins, CTs) are small rigid membrane-active proteins of the three-finger toxin (TFT) family. They comprise about 60 amino acid residues, stabilized by four disulphide bridges. CTs, the most abundant proteins in cobra venom are able to kill cancer cells in a dose and time-dependent manner.
Peter V, Dubovskii, Yuri N, Utkin
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The toxic proteins of cobra venom
Biochemical Pharmacology, 1968Abstract Carboxymethyl cellulose chromatography permits separation of five distinct toxic proteins from the venom of the Indian cobra ( Naja naja ). These account for 90 per cent of the toxicity against mice. After gel filtration on Sephadex G-50 columns, three of the toxic fractions are more potent than the crude venom by factors of 6–9. They differ
P R, Larsen, J, Wolff
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