Results 81 to 90 of about 13,049 (217)

Analysis of the efficacy of Taiwanese freeze-dried neurotoxic antivenom against Naja kaouthia, Naja siamensis and Ophiophagus hannah through proteomics and animal model approaches.

PLoS Neglected Tropical Diseases, 2017
In Southeast Asia, envenoming resulting from cobra snakebites is an important public health issue in many regions, and antivenom therapy is the standard treatment for the snakebite.
Chien-Chun Liu, Chen-Hsien You, Po-Jung Wang, Jau-Song Yu, Guo-Jen Huang, Chien-Hsin Liu, Wen-Chin Hsieh, Chih-Chuan Lin   +7 more
doaj   +1 more source

Hologenomics Reveals Specialized Dietary Adaptations in the Mengla Snail‐Eating Snake

Advanced Science, Volume 12, Issue 40, October 27, 2025.
Dietary adaptation studies from a holobiome perspective are scarce beyond mammals. This research reveals how genomic and microbial interactions drive dietary specialization in the Mengla snail‐eating snake, with evidence of gut symbiont convergence between reptiles and mammals.
Chaochao Yan, Xin‐Ning Li, Zhong‐Liang Peng, Wei Wu, Zeng Wang, Zhao‐Ran Zhu, Jia‐Chang Liu, Yao Wang, Jin‐Long Ren, Zhi‐Yi Zhang, Jia‐Tang Li   +10 more
wiley   +1 more source

Exceptional Visual‐Opsin Coexpression and Phenotypic Diversity in Outer‐Retinal Photoreceptors of Caenophidian Snakes

Journal of Comparative Neurology, Volume 533, Issue 10, October 2025.
In snakes, profound differences in retinal architecture are observed between diurnal and nocturnal species. Additionally, in the rod‐dominated retinas of nocturnal snakes, coexpression of the cone opsins SWS1 and LWS in individual cones is common, while rhodopsin (RH1) is restricted to typical rods.
Einat Hauzman, Silke Haverkamp, Juliana H. Tashiro, Irene L. Gügel, Natalia F. Torello‐Viera, Thaís B. Guedes, Pavel Němec, Nicholas R. Casewell, Cassandra M. Modahl, Maria Ermelinda Oliveira, Ana Lúcia C. Prudente, Daniel O. Mesquita, Dora Fix Ventura, David J. Gower   +13 more
wiley   +1 more source

The Proteome of African Spitting and Non‐Spitting Cobra Venoms and Cytotoxicity Against Pancreatic Cancer Cells

Journal of Applied Toxicology, Volume 45, Issue 10, Page 2055-2067, October 2025.
ABSTRACT African cobra (Naja spp.) venom contains toxins dominated by proteins and peptides with inter‐ and intra‐specific variations. There are several FDA‐approved drugs from snake venom toxins from other regions, including South America and Asia. Profiling the proteomes of medically important African cobra venoms from different locations will aid in
Benedict C. Offor, Beric Muller, Lesetja R. Motadi, Lizelle A. Piater   +3 more
wiley   +1 more source

Exploring gaps, biases, and research priorities in the evidence for reptile conservation actions

Conservation Biology, Volume 39, Issue 5, October 2025.
Abstract With over 21% of reptile species threatened with extinction, there is an urgent need to ensure conservation actions to protect and restore populations are informed by relevant, reliable evidence. We examined the geographic and taxonomic distribution of 707 studies that tested the effects of actions to conserve reptiles synthesized in ...
Oliver Speight, William H. Morgan, Thomas B. White, Katie A. Sainsbury, Amos Bouskila, Guy Rotem, Rebecca K. Smith, William J. Sutherland, Maggie J. Watson, Alec P. Christie   +9 more
wiley   +1 more source

Respiratory Muscle Injury Following Acute Monocled Cobra (Naja kaouthia) Envenoming: Histopathological Study in Rat Diaphragm

Current Issues in Molecular Biology
Clinical symptoms of monocled cobra (Naja kaouthia) envenoming include the paralysis of extraocular muscles, local tissue necrosis and death through respiratory failure.
Wanida Chuaikhongthong, Wipapan Khimmaktong, Natyamee Thipthong, Nissara Lorthong, Janeyuth Chaisakul   +4 more
doaj   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, Volume 599, Issue 18, Page 2644-2662, September 2025.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Experimental Study on Antidotal Activity of Musa × paradisiaca Linn. in Cobra Poison on Wistar Strain Albino Rats

Journal of Ayurveda
Introduction:Snake bite is an acute emergency which requires proper care and treatment. Today, the management of snake bites is done by administering anti-snake venom (ASV). The scarcity of ASV contributes to fatality. This scarcity of ASV is a result of
V. Revathy, S. Ravikrishna, Sudhakar Bhat, K. Sreejith, Chaithra Hebbar   +4 more
doaj   +1 more source

Restoration of adenosine deaminase, histamine, and IgE in organs of mice injected with cobra venom followed by specific treatment and reversal period

Journal of Venomous Animals and Toxins including Tropical Diseases, 2003
Adenosine deaminase (ADA), histamine, and IgE are endogenously present in animals. Research from this laboratory reported decreased levels of these substances in organs of mice as a consequence of sub-lethal injection of Naja kaouthia venom.
B. V. Lipps
doaj   +1 more source

Venom-related transcripts from Bothrops jararaca tissues provide novel molecular insights into the production and evolution of snake venom. [PDF]

, 2014
Attempts to reconstruct the evolutionary history of snake toxins in the context of their co-option to the venom gland rarely account for nonvenom snake genes that are paralogous to toxins, and which therefore represent important connectors to ancestral ...
Bastos, Carolina Mancini Val, Casewell, Nicholas, Ho, Paulo Lee, Junqueira-de-Azevedo, Inácio L M, Luna, Milene Schmidt, Yamanouye, Norma   +5 more
core   +3 more sources