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Bennett, A. Hughes+4 more
+15 more sources
The Cerebellum on Cocaine [PDF]
The traditional cerebellum's role has been linked to the high computational demands for sensorimotor control. However, several findings have pointed to its involvement in executive and emotional functions in the last decades. First in 2009 and then, in 2016, we raised why we should consider the cerebellum when thinking about drug addiction.
MIQUEL, MARTA+2 more
openaire +5 more sources
Dynamic Plasmonic System That Responds to Thermal and Aptamer-Target Regulations [PDF]
The DNA origami technique has empowered a new paradigm in plasmonics for manipulating light and matter at the nanoscale. This interdisciplinary field has witnessed vigorous growth, outlining a viable route to construct advanced plasmonic architectures with tailored optical properties. However, so far plasmonic systems templated by DNA origami have been
arxiv +1 more source
Joint modeling of longitudinal drug using pattern and time to first relapse in cocaine dependence treatment data [PDF]
An important endpoint variable in a cocaine rehabilitation study is the time to first relapse of a patient after the treatment. We propose a joint modeling approach based on functional data analysis to study the relationship between the baseline longitudinal cocaine-use pattern and the interval censored time to first relapse.
arxiv +1 more source
Machine learning analysis of cocaine addiction informed by DAT, SERT, and NET-based interactome networks [PDF]
Cocaine addiction is a psychosocial disorder induced by the chronic use of cocaine and causes a large of number deaths around the world. Despite many decades' effort, no drugs have been approved by the Food and Drug Administration (FDA) for the treatment of cocaine dependence. Cocaine dependence is neurological and involves many interacting proteins in
arxiv