Results 181 to 190 of about 11,001,215 (252)
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau +8 more
wiley +1 more source
Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi +2 more
wiley +1 more source
For aptamers to be adapated into function electrochemical sensors, the binding‐induced conformational change has to occur within a short distance away from the electrode surface. Aptamers that undergo structural rearrangement upon ligand binding have increasingly been translated into sensing platforms such as electrochemical aptamer‐based biosensors ...
Minh‐Dat Nguyen +6 more
wiley +1 more source
FOXP1+ and nNOS+ neurons constitute distinct neuronal populations in the adult subthalamic nucleus, with spatial segregation in rodents but extensive intermixing in humans. The human STN also shows an expanded nNOS+ population and increased FOXP1+/nNOS+ colocalization, highlighting species‐specific differences in STN organization.
Tila Medenica +3 more
wiley +1 more source
Assessing the use of ASAP‐MS for Screening a UK Pub for Illicit Drug Substances
ABSTRACT Illicit drug use in social environments, such as pubs and bars, has become an increasingly significant issue for public health and safety. These venues often provide a setting where individuals may engage in recreational drug use, resulting in their residual presence on high‐contact surfaces.
Andriana Michailidis +6 more
wiley +1 more source
Abstract Substance use complicates upward of 10% of US pregnancies. The Society for Maternal‐Fetal Medicine, the American College of Obstetricians and Gynecologists, and the American Society of Addiction Medicine have jointly recommended universal screening for substance use during pregnancy using a validated tool, without recommending universal ...
Society for Maternal‐Fetal Medicine (SMFM) +8 more
wiley +1 more source
Abstract Objective Peripartum opioid‐related mortality has increased in recent years, and social determinants of health (SDOH) are associated with adverse maternal outcomes. We sought to identify risk factors (including SDOH risk factors) for 180‐day postpartum readmissions related to opioid use among individuals without a documented diagnosis of ...
India Perez‐Urbano +3 more
wiley +1 more source
This naturalistic feasibility study explored the effects of alcohol and cannabis co‐intoxication on behavioural performance and brain activity using electroencephalography. A performance monitoring task was administered three times over 4.5‐h at sober, intoxication, and recovery timepoints.
Eleftherios M. Hetelekides +4 more
wiley +1 more source
Photoletter to the editor: Diffuse cocaine-related purpura.
Debjeet Sarkar +6 more
semanticscholar +1 more source

