Results 181 to 190 of about 11,001,215 (252)

Therapeutic Prospects of Ketamine for Cataplexy in Narcolepsy Type 1: Evidence from a Human Case and a Murine Model

open access: yesAnnals of Neurology, Volume 100, Issue 5, Page 1023-1027, November 2026.
Narcolepsy type 1 is characterized by cataplexy, for which current treatments targeting monoaminergic, histaminergic, and GABAergic pathways may be ineffective or poorly tolerated. We report the case of a 34‐year‐old man with narcolepsy type 1, intolerant to standard therapies, who experienced marked and sustained cataplexy reduction with morning ...
Francois Ricordeau   +8 more
wiley   +1 more source

Real‐Time Neurochemical Sensing in Zebrafish: Electrochemical and Fluorescent Approaches

open access: yesAnalysis &Sensing, Volume 6, Issue 6, November 2026.
The use of zebrafish has emerged as a powerful approach for real‐time neurochemical measurements. This review highlights recent advances in electrochemical and fluorescent sensing strategies that enable dynamic measurements in live preparations of this complex vertebrate. These complementary approaches provide new insights into neurochemical signaling,
Piyanka Hettiarachchi   +2 more
wiley   +1 more source

Systematic Evolution of Ligands by Exponential Enrichment to Sensor: Translating an Aptamer Into a Functional Electrochemical Sensor

open access: yesAnalysis &Sensing, Volume 6, Issue 6, November 2026.
For aptamers to be adapated into function electrochemical sensors, the binding‐induced conformational change has to occur within a short distance away from the electrode surface. Aptamers that undergo structural rearrangement upon ligand binding have increasingly been translated into sensing platforms such as electrochemical aptamer‐based biosensors ...
Minh‐Dat Nguyen   +6 more
wiley   +1 more source

A Species‐Dependent Spatial Patterning of FOXP1 and nNOS Protein Expression in the Adult Mammalian Subthalamic Nucleus

open access: yesJournal of Comparative Neurology, Volume 534, Issue 11, November 2026.
FOXP1+ and nNOS+ neurons constitute distinct neuronal populations in the adult subthalamic nucleus, with spatial segregation in rodents but extensive intermixing in humans. The human STN also shows an expanded nNOS+ population and increased FOXP1+/nNOS+ colocalization, highlighting species‐specific differences in STN organization.
Tila Medenica   +3 more
wiley   +1 more source

Assessing the use of ASAP‐MS for Screening a UK Pub for Illicit Drug Substances

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 11, November 2026.
ABSTRACT Illicit drug use in social environments, such as pubs and bars, has become an increasingly significant issue for public health and safety. These venues often provide a setting where individuals may engage in recreational drug use, resulting in their residual presence on high‐contact surfaces.
Andriana Michailidis   +6 more
wiley   +1 more source

Society for Maternal‐Fetal Medicine Special Statement: Guidance to reduce racial disparities in substance use screening and biological testing in pregnancy at the delivery admission

open access: yesPregnancy, Volume 2, Issue 6, November 2026.
Abstract Substance use complicates upward of 10% of US pregnancies. The Society for Maternal‐Fetal Medicine, the American College of Obstetricians and Gynecologists, and the American Society of Addiction Medicine have jointly recommended universal screening for substance use during pregnancy using a validated tool, without recommending universal ...
Society for Maternal‐Fetal Medicine (SMFM)   +8 more
wiley   +1 more source

Social determinants of health associated with newly documented opioid‐related postpartum readmissions

open access: yesPregnancy, Volume 2, Issue 6, November 2026.
Abstract Objective Peripartum opioid‐related mortality has increased in recent years, and social determinants of health (SDOH) are associated with adverse maternal outcomes. We sought to identify risk factors (including SDOH risk factors) for 180‐day postpartum readmissions related to opioid use among individuals without a documented diagnosis of ...
India Perez‐Urbano   +3 more
wiley   +1 more source

Neurophysiological and Behavioural Effects of Combined Cannabis Concentrates and Alcohol Among People Who Regularly Use Alcohol and Cannabis

open access: yesAddiction Biology, Volume 31, Issue 11, November 2026.
This naturalistic feasibility study explored the effects of alcohol and cannabis co‐intoxication on behavioural performance and brain activity using electroencephalography. A performance monitoring task was administered three times over 4.5‐h at sober, intoxication, and recovery timepoints.
Eleftherios M. Hetelekides   +4 more
wiley   +1 more source

Photoletter to the editor: Diffuse cocaine-related purpura.

open access: yesJournal of Dermatological Case Reports, 2013
Debjeet Sarkar   +6 more
semanticscholar   +1 more source

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