Results 31 to 40 of about 11,001,215 (252)

Cocaine use disorder in females is associated with altered social decision-making: a study with the prisoner’s dilemma and the ultimatum game

BMC Psychiatry, 2019
Background Chronic cocaine use is associated with cognitive deficits, including poor performance on neuropsychological tasks of memory, executive functions, theory of mind and decision-making.
Thiago Wendt Viola, João Paulo Otolia Niederauer, Bruno Kluwe-Schiavon, Breno Sanvicente-Vieira, Rodrigo Grassi-Oliveira   +4 more
doaj   +1 more source

Early-life adversity facilitates acquisition of cocaine self-administration and induces persistent anhedonia

Neurobiology of Stress, 2018
Early-life adversity increases the risk for emotional disorders such as depression and schizophrenia. Anhedonia, thought to be a core feature of these disorders, is provoked by our naturalistic rodent model of childhood adversity (i.e., rearing pups for ...
Jessica L. Bolton, Christina M. Ruiz, Neggy Rismanchi, Gissell A. Sanchez, Erik Castillo, Jeff Huang, Christopher Cross, Tallie Z. Baram, Stephen V. Mahler   +8 more
doaj   +1 more source

Stable self-serving personality traits in recreational and dependent cocaine users. [PDF]

PLoS ONE, 2017
Chronic cocaine use has been associated with impairments in social cognition, self-serving and antisocial behavior, and socially relevant personality disorders (PD).
Boris B Quednow, Lea M Hulka, Katrin H Preller, Markus R Baumgartner, Christoph Eisenegger, Matthias Vonmoos   +5 more
doaj   +1 more source

Childhood trauma subtypes may influence the pattern of substance use and preferential substance in men with alcohol and/or crack-cocaine addiction

Brazilian Journal of Psychiatry, 2022
Objective: To compare the prevalence and subtypes of childhood maltreatment (CM) between individuals with and without substance use disorder (SUD) and investigate the influence of different traumas on the preferential use of substances and the severity ...
Aline Hoffmann, Daniela Benzano, Felipe Ornell, Felix H.P. Kessler, Lisia von Diemen, Jaqueline B. Schuch   +5 more
doaj   +1 more source

Smoked cocaine in socially-depressed areas [PDF]

, 2010
Background: The main objectives of this study are to describe the smoked cocaine user's profile in socially-depressed areas and their needs from a harm-reduction perspective, to investigate their use of smoking crack and compare the acute effects between
Pons-Prat, Montserrat, Olga Díaz, Delás, Jordi, Elena Adán, Pons Montserrat, Díaz Olga, Aguas Compaired, M. (Margarita), Adan, Elena, Adán Elena, Margarita Aguas, Diaz, Olga, Montserrat Pons, Aguas Margarita, Jordi Delas, Delas Jordi, Fuertes Ricardo, Ricardo Fuertes, Fuertes, Ricardo   +17 more
core   +1 more source

Galanin Receptors as Pharmacological Targets in the Treatment of Addiction,Drug Rehabilitation, Drug Addiction Treatment,Morphine Addiction, Drug Addiction Treatment, Cocaine-Related Disorders, Cocaine Addiction, Opioid-Related Disorders, Substance-Related Disorders

, 2012
Drug and alcohol abuse present an ongoing problem from both a financial and psychosocial perspective. As the worldwide prevalence of drug-abuse grows, research into the use of novel pharmacotherapies continues. Recently, the neuropeptide galanin has been
Belinda L. Ash, E. Djouma
semanticscholar   +1 more source

INFLUENCE OF COCAINE-RELATED IMAGES AND ALCOHOL ADMINISTRATION ON INHIBITORY CONTROL IN COCAINE USERS

Alcoholism: Clinical and Experimental Research, 2017
Background Alcohol use and impulsivity, including decreased inhibitory control, predict poor treatment outcomes for individuals with cocaine use disorders.
E. Pike, Katherine R. Marks, William W. Stoops, C. Rush   +3 more
semanticscholar   +1 more source

Objective and specific tracking of anhedonia via event-related potentials in individuals with cocaine use disorders

Drug and Alcohol Dependence, 2016
Background Hyposensitivity to non-drug reward, behaviorally manifested as anhedonia, is a hallmark of chronic substance use. Anhedonia is a transdiagnostic symptom underpinned by neurobiochemical disturbances in the reward circuit, yet an objective ...
M. Parvaz, Vilma Gabbay, P. Malaker, R. Goldstein   +3 more
semanticscholar   +1 more source

Increased conditioned place preference for cocaine in high anxiety-related behavior (HAB) mice is associated with an increased activation in the accumbens corridor

Frontiers in Behavioral Neuroscience, 2014
Anxiety disorders and substance use disorders are strongly associated in humans. Accordingly, a widely held but controversial concept in the addiction field, the so-called self-medication hypothesis, posits that anxious individuals are more vulnerable ...
Janine Maria Prast, Aurelia eSchardl, Simone B Sartori, Nicolas eSingewald, Alois eSaria, Gerald eZernig, Gerald eZernig   +6 more
doaj   +1 more source

Identification of Functional CircRNA–miRNA–mRNA Regulatory Network in Dorsolateral Prefrontal Cortex Neurons of Patients With Cocaine Use Disorder

Frontiers in Molecular Neuroscience, 2022
Increasing evidence has indicated that circular RNAs (circRNAs) act as competing endogenous RNAs (ceRNAs) regulatory network to regulate the expression of target genes by sponging microRNAs (miRNAs), and therefore play an essential role in many ...
Yun Chen, Yun Chen, Xianfeng Li, Shiqiu Meng, Shihao Huang, Suhua Chang, Jie Shi, Jie Shi   +7 more
doaj   +1 more source