Role of oxidative stress in cocaine-induced cardiotoxicity and cocaine-related death.
Current Medicinal Chemistry, 2012 Cocaine-induced cardiovascular disorders such as hypertension, thrombosis, myocardial dysfunction, cardiac dysrhythmias and endocarditis have received widespread attention in the context of cocaine abuse.
Daniela Cerretani +5 more
semanticscholar +3 more sources
Frontiers in Behavioral Neuroscience, 2021 The role of glucagon-like peptide 1 (GLP-1) in insulin-dependent signaling is well-known; GLP-1 enhances glucose-dependent insulin secretion and lowers blood glucose in diabetes.
Candan Yasemin Eren-Yazicioglu +3 more
semanticscholar +1 more source
Pharmacotherapy for Cocaine Use Disorders [PDF]
, 2021 Cocaine is one of the most commonly used substances worldwide. It has a strong addictive potential, which often leads to excessive consumption causing pronounced physical and psychological harm to users.
Engeli, Etna J E; https://orcid.org/ +2 more
core +1 more source
Alterations of Stress-Related Glucocorticoids and Endocannabinoids in Hair of Chronic Cocaine Users
International Journal of Neuropsychopharmacology, 2021 Background Previous research in animals and humans has demonstrated a potential role of stress regulatory systems, such as the hypothalamic-pituitary-adrenal (HPA) axis and the endocannabinoid (eCB) system, in the development of substance use disorders ...
C. Voegel +7 more
semanticscholar +1 more source
Drug and Alcohol Dependence, 2021 Background In clinical trials of pharmacotherapy for substance use, abstinence is the primary endpoint accepted by regulatory agencies. However, this endpoint could be overly restrictive, impeding efforts to identify effective medications for cocaine use
E. Aharonovich +3 more
semanticscholar +1 more source
Cannabidiol prevents several of the behavioral alterations related to cocaine addiction in mice.
Progress in Neuro-psychopharmacology and Biological Psychiatry, 2021 Cocaine dependence is a highly prevalent disease in modern society and lacks an effective treatment. Cannabidiol (CBD), a major non-psychoactive constituent of Cannabis sativa, has been shown to be a promising tool in the management of some ...
Juan Carlos Ledesma +2 more
semanticscholar +1 more source
The Distribution of opiates, cocaine and their metabolites in skeletal muscle tissue and vitreous humour as an aid to post-mortem toxicological interpretation. [PDF]
Post-mortem blood drug concentrations vary greatly and as a consequence of post-mortem change and redistribution may not reflect the concentration at the time of death.
Rees, Kelly-Ann
core +5 more sources
Cocaine‐related attentional bias following trauma cue exposure among cocaine dependent in‐patients with and without post‐traumatic stress disorder [PDF]
Addiction, 2011 ABSTRACTAims Although the co‐occurrence of post‐traumatic stress disorder (PTSD) and cocaine dependence is associated with a wide range of negative clinical outcomes, little is known about the mechanisms that underlie this association. This study investigated one potential mechanism—attentional bias to cocaine imagery following trauma cue exposure ...
Matthew T, Tull +4 more
openaire +2 more sources
AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Carryover effects to addiction-associated stimuli in a group of marijuana and cocaine users [PDF]
, 2009 Addiction has been characterized as an attentional bias towards drug-related cues. In two experiments we investigate the effects of non-words that have been associatively trained to addiction-related images in a group of marijuana and cocaine users ...
Money, Sharon +3 more
core +1 more source