Results 61 to 70 of about 11,001,215 (252)

Oral changes in cocaine abusers: an integrative review

Brazilian Journal of Otorhinolaryngology, 2022
Introduction: Cocaine is one of the most often used psychoactive drugs worldwide, being extracted from the leaves of Erytroxylus coca plant. Its abusive use can trigger several consequences for the human body, including the oral cavity.
César Antonio Araújo Melo, Hanna Rabech Garcia Guimarães, Raphael Crhistian Fernandes Medeiros, Georgia Costa de Araújo Souza, Patrícia Bittencourt Dutra dos Santos, Ana Clara Soares Paiva Tôrres   +5 more
doaj   +1 more source

Healing together: Results from a pilot trial of 3,4‐Methylenedioxymethamphetamine‐enhanced cognitive‐behavioral conjoint therapy for posttraumatic stress disorder

Journal of Traumatic Stress, EarlyView.
Abstract Posttraumatic stress disorder (PTSD) disrupts individual well‐being and relationship health, particularly among veteran/military couples with heightened risks due to deployment, family reintegration, and traumatic stress. Although cognitive‐behavioral conjoint therapy (CBCT) and brief CBCT (bCBCT) have demonstrated strong efficacy in reducing ...
Leslie A. Morland, Chandra E. Khalifian, Dimitri Perivoliotis, Bettye Chargin, Al Alam, Tamara R. Wachsman, Dhakshin Ramanathan, Andrew W. Bismark, Christopher Stauffer, Anne C. Wagner, Abigail C. Angkaw, Kayla C. Knopp   +11 more
wiley   +1 more source

Plasma Cell Mucositis: A 20‐Year Retrospective Review at a Tertiary Center

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Plasma cell mucositis (PCM) is a rare, chronic inflammatory condition of mucosal surfaces that is likely underdiagnosed and underreported, with limited data on its clinical characteristics, extracavitary involvement, and treatment outcomes.
Miguel A. Aristizabal‐Torres, Jessi M. Larrinaga, Katherine Bodiford, Olayemi Sokumbi, Leila Tolaymat   +4 more
wiley   +1 more source

Perspectives on drugs: Emergency health consequences of cocaine use in Europe. [PDF]

, 2014
Several thousands of cocaine-related emergencies are reported in Europe every year, representing a considerable burden on services. In this analysis, the EMCDDA studies the type of cocaine-related problems reported and the potential of using hospital ...

core  

Developing the Dopamine D3 Receptor (D3R) Antagonist, (R)‐VK4‐116, as a Non‐Opioid Medication for the Treatment of Opioid Use Disorder

Medicinal Research Reviews, EarlyView.
ABSTRACT Opioid use disorder (OUD) remains a major global health challenge, and currently approved treatments (methadone, buprenorphine, and naltrexone) are all opioid receptor‐targeting drugs with limitations in access, adherence, stigma, and use in polysubstance use disorders. Because the dopamine D3 receptor (D3R) is enriched in limbic brain regions
Chia‐Kuei Wu, Yu‐Chih Lin, Junfeng Huang, Bangwei Ding, Pramod Terse, Rahul Nandre, Haksong Jin, Molly Congdon, Kun Shen, Philip Sanderson, Gregory Tawa, Stephanie Mounaud, Marta De Santis, Donald Lo, Elizabeth A. Ottinger, Amy Hauck Newman   +15 more
wiley   +1 more source

Corticotrophin-releasing hormone binding protein in the basolateral amygdala: divergent roles in cocaine and opioid addiction like behaviors

Addiction Neuroscience
Cocaine and oxycodone use disorders represent urgent public health burdens, with limited treatment options for opioid dependence and no approved pharmacotherapies for cocaine-related disorders, highlighting the critical need to uncover novel molecular ...
Courtney P. Wood, Arnav Gurha, Caitlin Crook, Angelica Martinez, Selen Dirik, Cloe Moreno, Anirudh Vaiyapuri, Avraham Libster, Francesca Telese, Giordano de Guglielmo   +9 more
doaj   +1 more source

Environmental enrichment alters protein expression as well as the proteomic response to cocaine in rat nucleus accumbens

Frontiers in Behavioral Neuroscience, 2014
Prior research demonstrated that environmental enrichment creates individual differences in behavior leading to a protective addiction phenotype in rats.
Cheryl F. Lichti, Xiuzhen eFan, Xiuzhen eFan, Robert D. English, Yafang eZhang, Yafang eZhang, Dingge eLi, Dingge eLi, Fanping eKong, Mala eSinha, Clark R. Andersen, Heidi eSpratt, Heidi eSpratt, Heidi eSpratt, Bruce A. Luxon, Bruce A. Luxon, Thomas A. Green, Thomas A. Green   +17 more
doaj   +1 more source

Fetal Intracranial Hemorrhage: What to Tell Expecting Parents?

Prenatal Diagnosis, EarlyView.
ABSTRACT Fetal intracranial hemorrhage (ICH) is a rare but serious prenatal diagnosis, and counseling affected families remains challenging. In this narrative review, we summarize current evidence on the classification, epidemiology, etiology, diagnosis and neurodevelopmental outcomes of fetal ICH, with a primary focus on intraventricular hemorrhage ...
Shiri Shinar, Yada Kunpalin, Elka Miller
wiley   +1 more source

Intranasal diamorphine population pharmacokinetics modeling and simulation in pediatric breakthrough pain

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 435-447, March 2025.
Abstract Intranasal diamorphine (IND), approved for managing breakthrough pain in the UK, has been identified as an acceptable alternative offering effective, expedient, and less traumatic analgesia for children. However, the current dose regimen in pediatric populations relies on clinical expertise while the pharmacokinetics properties are poorly ...
Lianjin Cai, Jingchen Zhai, Beihong Ji, Fengyang Han, Taoyu Niu, Luxuan Wang, Junmei Wang   +6 more
wiley   +1 more source

Predictors of initiation of nicotine, alcohol, cannabis, and cocaine use: Results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC)

American Journal on Addictions, 2018
BACKGROUND AND OBJECTIVES There may be substantial overlap in the risk factors for substance use and substance use disorders (SUD). Identifying risk factors for substance use initiation is essential for understanding the etiology and natural history of ...
C. Blanco, Ludwing Flórez-Salamanca, R. Secades-Villa, Shuai Wang, D. Hasin   +4 more
semanticscholar   +1 more source