Results 81 to 90 of about 11,001,215 (252)

The relative prevalence of schizophrenia among cannabis and cocaine users attending addiction services [PDF]

, 2018
Background: Cannabis and cocaine are the most common illicit drugs for which people are treated in addiction services in Latin America. Much research has suggested that the use of cannabis increases the risk of schizophrenia; there is less evidence ...
Robin M. Murray, Nicolás Libuy, Valeria de Angel, Ibáñez, Carlos, Murray, Robin M., Carlos Ibáñez, Libuy, Nicolás, Adrian P. Mundt, Libuy Hidalgo, Nicolás, Mundt, Adrian P, Murray, Robin M, Angel, Valeria de, de Angel, Valeria, Mundt, Adrian P., de Angel, Valeria; id_orcid, Ibáñez Berríos, Carlos   +15 more
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From Conflicting Outcomes to Mutual Losses: How Punitive Responses to Problematic Substance Use Suppress Help‐Seeking and Cause Harm

Human Resource Management Journal, EarlyView.
ABSTRACT Problematic substance use (PSU) is a significant, inadequately managed people management challenge. Drawing on the conflicting outcomes and mutual losses perspectives on HRM and employee wellbeing, and using Job Demands‐Resources theory to explain underlying strain‐driven loss cycles, we examine factors shaping PSU and help‐seeking among 575 ...
Karen Maher, Aoife M. McDermott, Andrew Clements, Emmert Roberts, Sally Pezaro   +4 more
wiley   +1 more source

Evaluation of plasma cytokines in patients with cocaine use disorders in abstinence identifies transforming growth factor alpha (TGFα) as a potential biomarker of consumption and dual diagnosis

PeerJ, 2017
Background Cocaine use disorder (CUD) is a complex health condition, especially when it is accompanied by comorbid psychiatric disorders (dual diagnosis). Dual diagnosis is associated with difficulties in the stratification and treatment of patients. One
Rosa Maza-Quiroga, N. García-Marchena, P. Romero-Sanchiz, V. Barrios, M. Pedraz, A. Serrano, R. Nogueira-Arjona, J. J. Ruiz, M. Soria, R. Campos, J. Chowen, J. Argente, M. Torrens, M. López-Gallardo, E. Marco, F. Rodríguez de Fonseca, F. Pavón, P. Araos   +17 more
semanticscholar   +1 more source

Unraveling Suicidal Ideation and Behaviors in a Global Cohort of Individuals at Clinical High‐Risk for Psychosis: Multivariable Correlates and Subthreshold Psychotic Symptoms

Acta Psychiatrica Scandinavica, EarlyView.
ABSTRACT Introduction Suicidal ideation and behaviors (SIB) are common among individuals at clinical high risk for psychosis (CHR‐P), but their relationship with the overall clinical profile remains unclear. This study aimed to identify sociodemographic/clinical factors associated with SIB in CHR‐P individuals and to examine whether subthreshold ...
Stefano Damiani, Marika Orlandi, Umberto Provenzani, Elisa Bortolin, Margherita Rovida, Riccardo Stefanelli, Jean Addington, Luis Alameda, Celso Arango, Nicholas J. K. Breitborde, Matthew R. Broome, Kristin S. Cadenhead, Monica E. Calkins, Ricardo E. Carrion, Rolando I. Castillo‐Passi, Eric Yu Hai Chen, Jimmy Choi, Philippe Conus, Barbara A. Cornblatt, Covadonga M. Diaz‐Caneja, Lauren M. Ellman, Abigayle Fogarty, Pablo A. Gaspar, Carla Gerber, Louise Birkedal Glenthøj, Leslie E. Horton, Christy Lai Ming Hui, Joseph Kambeitz, Lana Kambeitz‐Ilankovic, Matcheri S. Keshavan, Minah Kim, Sung‐Wan Kim, Nikolaos Koutsouleris, Zsuliet Kristof, Jun Soo Kwon, Kerstin Langbein, Daniel Mamah, Daniel H. Mathalon, Vijay A. Mittal, Josh Nguyen, Merete Nordentoft, Godfrey D. Pearlson, Nora Penzel, Jesus Perez, Diana O. Perkins, Albert R. Powers III, Jack Rogers, Fred W. Sabb, Jason Schiffman, Jai L. Shah, Steven M. Silverstein, Stefan Smesny, William S. Stone, Gregory P. Strauss, Judy L. Thompson, Rachel Upthegrove, Swapna Verma, Cassandra Wannan, Jijun Wang, Heather Wastler, Daniel H. Wolf, Tianhong Zhang, Sylvain Bouix, Cheryl M. Corcoran, Tina Kapur, Ofer Pasternak, Carrie E. Bearden, Rene S. Kahn, John M. Kane, Patrick D. McGorry, Barnaby Nelson, Martha E. Shenton, Scott W. Woods, Paolo Fusar‐Poli   +73 more
wiley   +1 more source

Impaired extinction of cocaine seeking in HIV-infected mice is accompanied by peripheral and central immune dysregulation

Communications Biology
Substance use disorders (SUDs) are highly comorbid with HIV infection, necessitating an understanding of the interactive effects of drug exposure and HIV.
Lauren A. Buck, Qiaowei Xie, Michelle Willis, Christine M. Side, Laura L. Giacometti, Peter J. Gaskill, Kyewon Park, Farida Shaheen, Lili Guo, Santhi Gorantla, Jacqueline M. Barker   +10 more
doaj   +1 more source

The Effects of Cocaine and Heroin Prices on Drug-Related Emergency Department Visits [PDF]

This paper estimates the empirical relationship between the prices of cocaine and heroin and objective indicators of use. The set of outcomes is drug related hospital emergency department admissions where cocaine and heroin are cited, for 21 large U.S ...
Dhaval Dave
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Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

Addiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper, Francesca Small, Sam Brown, Michael Kelleher, Luke Mitcheson, James Rucker, Allan H. Young, John Marsden   +7 more
wiley   +1 more source

Cocaine Upregulates Microglial Lipid Droplet Formation Through Increasing Lipid Synthesis Activity In Vitro and In Vivo

Biomolecules
A novel subtype of microglia, lipid droplet accumulation microglia (LDAMs), has been identified in the aged brain, which is characterized by sustained inflammation and senescent-like phenotypes.
Yan Cheng, Brooke Russell, Liam Liyang Guo, Aryan Patel, Yan Y. Sanders, Ming-Lei Guo   +5 more
doaj   +1 more source

In silico identification and in vivo validation of miR-495 as a novel regulator of motivation for cocaine that targets multiple addiction-related networks in the nucleus accumbens

Molecular Psychiatry, 2017
MicroRNAs (miRNAs) are important post-transcriptional regulators of gene expression and are implicated in the etiology of several neuropsychiatric disorders, including substance use disorders (SUDs).
Ryan M. Bastle, Robert J. Oliver, Amy S. Gardiner, Nathan S. Pentkowski, F. Bolognani, Andrea M. Allan, Trisha Chaudhury, Madeleine St. Peter, Nick Galles, Colton D. Smith, J. Neisewander, N. Perrone-Bizzozero   +11 more
semanticscholar   +1 more source

Fiscal Year 2012

, 2012
Annual financial report of the Texas Council on Alzheimer's Disease and Related Disorders documenting income, expenditures, and other relevant financial information for fiscal year ...
Texas Council on Alzheimer's Disease & Related Disorders
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