Results 91 to 100 of about 265,487 (267)

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

Addiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden, Michael Kelleher, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, Claire Roberts, James J. Rucker, Gemma Scott, Ivan Saeger, Francesca Small, Mathieu Seynaeve   +10 more
wiley   +1 more source

Varenicline for cannabis use disorder: A randomized controlled trial

Addiction, EarlyView.
Abstract Background and aims Although cannabis use is widespread and prevalence of cannabis use disorder (CUD) is increasing, limited advancements have been made in CUD medication development. The objective of this study was to test the efficacy of varenicline with medical management for reducing cannabis use in treatment‐seeking individuals with CUD ...
Aimee L. McRae‐Clark, Kevin M. Gray, Nathaniel L. Baker, Brian J. Sherman, Bryan Tolliver, Jessica Burt, Alonzo Steplight, Elizabeth Chapman, Amanda Wagner   +8 more
wiley   +1 more source

Addiction Phenomenology In Substance Use And Non-Substance Use Disorders

, 2008
There is growing research evidence and public concern over the burgeoning of disorders which share common features with substance addictions. In order to investigate the presence and role of addiction features in disorders outside of substance addictions,
McLachlan, Andre David
core  

Acute cocaine-related health problems in patients presenting to an urban emergency department in Switzerland: a case series [PDF]

, 2014
BACKGROUND Emergency departments may be a useful information source to describe the demographics and clinical characteristics of patients with acute cocaine-related medical problems.
Marcel Bruggisser, Bodmer, Michael, Liechti, Matthias E, Bruggisser, Marcel, Michael Bodmer, Liechti, Matthias E., Enzler, Florian, Evangelia Liakoni, Liakoni, Evangelia, Florian Enzler, Matthias E Liechti, Michael Bodmer   +11 more
core   +1 more source

The psychoactive effects of repeated ketamine infusions and their mechanistic role in the treatment of alcohol use disorder: Secondary analysis of a randomised controlled trial

Addiction, EarlyView.
Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy, Ananya Sarma, Bethan Marsh, Lorna Hardy, Meryem Grabski, Merve Mollaahmetoglu, Joshua Shotton, Shamhethan Bhaskaran, Anne Lingford‐Hughes, H. Val Curran, Celia Morgan, Will Lawn   +11 more
wiley   +1 more source

Psychiatric morbidity and readiness for change : a study of methamphetamine dependent subjects in Cape Town

, 2011
Methamphetamine users may suffer from a range of co-morbid psychiatric disorders. Predictors of treatment outcome in substance dependence may include both such co-morbidity and readiness for change.
Akindipe, Taiwo
core  

Healthcare utilization and mortality after overdose prevention site closure: A linked cohort analysis using segmented difference‐in‐differences time series

Addiction, EarlyView.
Abstract Background and aims Evidence regarding the impacts of supervised drug consumption services (SDC) remains mixed, and few evaluations have used individual‐level, linkable health data to examine service withdrawal. In September 2024, the Red Deer overdose prevention site (OPS) in Alberta, Canada, was scheduled for closure, with operations ceasing
Nathaniel Day, Kym Kaufmann, Daniel John Alexander Devoe, Vanja Grubac, Alessia DiMarzo, Haisa Osmanli, Vanessa Norton, Shelly Vik, Nickie Mathew, Robert Lawrence Tanguay, Anees Bahji   +10 more
wiley   +1 more source

Transcriptional impacts of substance use disorder and HIV on human ventral midbrain neurons and microglia

Nature Communications
For people with HIV, substance use disorders are a prominent neurological risk factor, and the impacts of both on dopaminergic pathways may pose a deleterious convergence. Here, we profile, at single nucleus resolution, substantia nigra transcriptomes of
Alyssa M. Wilson, Michelle M. Jacobs, Tova Y. Lambert, Aditi Valada, Gregory Meloni, Evan Gilmore, Jacinta Murray, Susan Morgello, Schahram Akbarian   +8 more
doaj   +1 more source

Crack lung - a case report [PDF]

Vojnosanitetski Pregled
Introduction. Crack cocaine (CC), a potent form of cocaine, is well-known for its rapid and intense effects on the central nervous system. Its detrimental impact on the respiratory system is often disregarded. This type of cocaine originates from cocaine
Vasiljević Mira, Šarac Sanja, Milić Rade, Lazović-Popović Biljana   +3 more
doaj   +1 more source

B-10SPECT Imaging in Adults with Cocaine-Related Disorders [PDF]

Archives of Clinical Neuropsychology, 2016
J Garcia, R Okolichany, M Blose, G Vitale, C Golden, D Amen, K Willeumier, D Taylor   +7 more
openaire   +1 more source