Results 71 to 80 of about 11,001,215 (252)

Impulsivity and Impulsivity-Related Endophenotypes in Suicidal Patients with Substance Use Disorders: an Exploratory Study

International Journal of Mental Health and Addiction, 2020
Suicidal behavior (SB) is a major problem in patients with substance use disorders (SUDs). However, little is known about specific SB risk factors in this population, and pathogenetic hypotheses are difficult to disentangle.
A. Costanza, S. Rothen, S. Achab, G. Thorens, M. Baertschi, K. Weber, A. Canuto, Hélène Richard-Lepouriel, N. Perroud, D. Zullino   +9 more
semanticscholar   +1 more source

Differences in Risk Factors for Severe Preeclampsia and HELLP Syndrome in Singleton Versus Twin Pregnancies: A Population‐Based Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To examine whether the associations between pre‐pregnancy risk factors and severe preeclampsia/eclampsia (SPE) and/or HELLP syndrome differ between singleton and twin pregnancies. Design A population‐based retrospective cohort study. Setting British Columbia (BC), Canada.
Mackenzie Campbell, Johanna Koegl, Jeffrey N. Bone, Sofia Nicolls, Janet Lyons, Chantal Mayer, Kenneth I Lim, Julie Van Schalkwyk, K. S. Joseph, Sarka Lisonkova, the ORQA group, A. Christoffersen‐Deb, S. Derikvand, S. John, L. Richter, M. Rougerie, Y. Sabr, M. Vidler   +17 more
wiley   +1 more source

Adolescent circadian rhythm disruption increases reward and risk-taking

Frontiers in Neuroscience
IntroductionCircadian rhythm disturbances have long been associated with the development of psychiatric disorders, including mood and substance use disorders.
Lauren M. DePoy, Lauren M. DePoy, Chelsea A. Vadnie, Chelsea A. Vadnie, Chelsea A. Vadnie, Kaitlyn A. Petersen, Kaitlyn A. Petersen, Madeline R. Scott, Madeline R. Scott, Wei Zong, RuoFei Yin, Ross C. Matthaei, Fernanda Juarez Anaya, Callie I. Kampe, George C. Tseng, Colleen A. McClung, Colleen A. McClung, Colleen A. McClung   +17 more
doaj   +1 more source

Delay and probability discounting of sexual and monetary outcomes in individuals with cocaine use disorders and matched controls.

PLoS ONE, 2015
Individuals with cocaine use disorders are disproportionately affected by HIV/AIDS, partly due to higher rates of unprotected sex. Recent research suggests delay discounting of condom use is a factor in sexual HIV risk.
Matthew W Johnson, Patrick S Johnson, Evan S Herrmann, Mary M Sweeney   +3 more
doaj   +1 more source

Fiscal Year 2022

, 2020
This report describes the activities and highlights accomplishments of the Texas Council on Alzheimer’s Disease and Related Disorders Council during fiscal years 2019 and 2020 and also provides recommendations for the following fiscal ...
Texas Council on Alzheimer's Disease & Related Disorders
core  

Forensic challenges in a case of suspected filicide, matricide, and post‐mortem dismemberment

Journal of Forensic Sciences, EarlyView.
Abstract Familicide represents one of the most complex forms of domestic violence in forensic practice. Among intrafamilial homicides, filicide and matricide pose major medico‐legal and criminological challenges, particularly when autopsy findings are nonspecific or severely altered by post‐mortem changes.
Isabella Caristo, Rosario Barranco, Giulio Fraternali Orcioni, Domenico Coviello, Francesco Ventura   +4 more
wiley   +1 more source

GC/MS determination of gabapentin in human plasma and vitreous humor and its application to forensic samples

Journal of Forensic Sciences, EarlyView.
Abstract Gabapentin (GBP) is widely prescribed off‐label, and cases of misuse, abuse, self‐medication, and intentional self‐harm have been reported. This study aimed to develop and validate a simple GC‐MS method for the determination of GBP in plasma and vitreous humor (VH) and to explore the relationship between concentrations in both matrices in ...
Pamela Cabarcos‐Fernández, Inés Sánchez‐Sellero, Iván Álvarez‐Freire, María Jesús Tabernero‐Duque, Ana María Bermejo‐Barrera   +4 more
wiley   +1 more source

Immunosuppressant treatment reduces cocaine-induced behavioral sensitization in mice

Frontiers in Pharmacology
BackgroundNeuroinflammation plays fundamental, though still not fully understood, roles in the pathophysiology of substance use disorders, including cocaine addiction. Chronic cocaine exposure promotes neuroinflammatory signaling and synaptic alterations
Gabriella Luciana de Oliveira, Maria Carolina Machado da Silva, Giovanni Freitas Gomes, Roberta dos Santos Ribeiro, Gabriela Reis Cussat, Rúbia Aparecida Fernandes, Jorge Lucas Nascimento Souza, Heliana de Barros Fernandes, Aline Silva de Miranda, Victor Rodrigues Santos, Lílian Lacerda Bueno, Luciene Bruno Vieira, Fabrício Araújo Moreira, Antônio Carlos Pinheiro de Oliveira   +13 more
doaj   +1 more source

Mucocutaneous leishmaniasis in a cocaine user: diagnostic and therapeutic knowledge

Revista da Sociedade Brasileira de Medicina Tropical, 2020
Mucocutaneous leishmaniasis (MCL) is a chronic infection that can affect the skin and mucous membranes. We report a case of oral, nasopharyngeal, and penile lesions in a 35-year-old cocaine user.
Lissiê Lunardi Sbroglio, Viviane Maria Maiolini, Irene Machado Moraes Alvarenga Rabelo, Gabriela Almeida Giraldelli, Luciana Patrícia Tuccori, Rodrigo Guimarães Cunha   +5 more
doaj   +1 more source

Enhancing VTA Cav1.3 L-type Ca2+ channel activity promotes cocaine and mood - related behaviors via overlapping AMPA receptor mechanisms in the nucleus accumbens

Molecular Psychiatry, 2017
Genetic factors significantly influence susceptibility for substance abuse and mood disorders. Rodent studies have begun to elucidate a role of Cav1.3 L-type Ca2+ channels in neuropsychiatric-related behaviors, such as addictive and depressive-like ...
Arlene Martínez-Rivera, J. Hao, Thomas F. Tropea, T. Giordano, Maria Kosovsky, Richard C. Rice, Amy Lee, R. Huganir, J. Striessnig, N. Addy, Shizhong Han, A. Rajadhyaksha   +11 more
semanticscholar   +1 more source