AASLD practice guidance on drug, herbal, and dietary supplement–induced liver injury
, 2022 Hepatology, EarlyView.
Robert J. Fontana +6 more
wiley +1 more source
Molecular Cages as Probes in Indicator Displacement Assays: The Case of Scopolamine Detection
Angewandte Chemie, EarlyView.In this research, we show the concept of molecular cages as probes in indicator displacement assays, focusing on scopolamine detection, a drug often used in drug‐facilitated sexual assaults. Drug sensing occurs via the drug‐induced transformation of non‐emissive [Fluorescein2⊂Cage] complex into [Scopolamine⊂Catenane] and highly emissive free ...
Giovanni Montà‐González +5 more
wiley +2 more sources
Oral Administration of Levo-Tetrahydropalmatine Attenuates Reinstatement of Extinguished Cocaine Seeking by Cocaine, Stress or Drug-Associated Cues in Rats [PDF]
, 2011 Cocaine addiction is characterized by a persistently heightened susceptibility to drug relapse. For this reason, the identification of medications that prevent drug relapse is a critical goal of drug abuse research.
Baker, David A. +9 more
core +2 more sources
"EFFECT OF APAMIN ON TOLERANCE TO COCAINE-INDUCED LOCOMOTOR ACTIVITY IN MICE" [PDF]
Acta Medica Iranica, 2004 In the present study, the effect of apamin (potassium channel blocker) on tolerance to cocaine-induced locomotor activity in mice has been investigated.
H. R. Jamshidi +1 more
doaj +2 more sources
Initial d2 dopamine receptor sensitivity predicts cocaine sensitivity and reward in rats. [PDF]
PLoS ONE, 2013 The activation of dopamine receptors within the mesolimbic dopamine system is known to be involved in the initiation and maintenance of cocaine use. Expression of the D2 dopamine receptor subtype has been implicated as both a predisposing factor and ...
Kathryn E Merritt, Ryan K Bachtell
doaj +1 more source
Associations amongst form of cocaine used (powder vs crack vs both) and HIV-related outcomes
Addictive Behaviors Reports, 2021 Introduction: Cocaine (including powder and crack) use is common among people with HIV (PWH). We identified socio-demographic and behavioral factors associated with cocaine use (overall and various forms) among PWH; we also examined differences in HIV ...
Yiyang Liu +4 more
doaj +1 more source
Reduced GABA-B/GIRK-mediated regulation of the VTA following a single exposure to cocaine [PDF]
, 2012 In this paper, Arora and colleagues expand on their previous work on GIRK channels in the ventral tegmental area (VTA) presenting evidence that a single exposure to cocaine reduces inhibitory GABAergic transmission to dopamine (DA) neurons in the ventral
Andrew Varnell +2 more
core +2 more sources
Frontiers in Neuroscience, 2022 Studies using either continuous or intermittent access cocaine self-administration procedures showed that cocaine seeking increases during abstinence (incubation of cocaine craving), and that this effect is higher after intermittent cocaine access. Other
Celine Nicolas +3 more
doaj +1 more source
Dnmt3a regulates emotional behavior and spine plasticity in the nucleus accumbens. [PDF]
, 2010 Despite abundant expression of DNA methyltransferases (Dnmts) in brain, the regulation and behavioral role of DNA methylation remain poorly understood. We found that Dnmt3a expression was regulated in mouse nucleus accumbens (NAc) by chronic cocaine use ...
Bolaños, Carlos A +26 more
core +3 more sources
Aptamer-based cocaine assay using a nanohybrid composed of ZnS/Ag2Se quantum dots, graphene oxide and gold nanoparticles as a fluorescent probe [PDF]
, 2020 Authors report on a new fluoro-graphene-plasmonic nanohybrid aptamer-based fluorescent nanoprobe for cocaine. To construct the nanoprobe, newly synthesized glutathione-capped ZnS/Ag 2Se quantum dots (QDs) were first conjugated to graphene oxide (GO) to ...
Abdolvand, Amin +4 more
core +2 more sources