Results 61 to 70 of about 40,355 (156)
Toxicology Reports, 2019 Crack cocaine smokers inhale, alongside with cocaine, its pyrolysis product, anhydroecgonine methyl ester (AEME). We have previously described AEME neurotoxic effect and its additive effect when co-incubated with cocaine.
Raphael Caio Tamborelli Garcia +6 more
doaj
Sample size estimation for comparing dynamic treatment regimens in a SMART: a Monte Carlo-based approach and case study with longitudinal overdispersed count outcomes [PDF]
arXiv, 2021 Dynamic treatment regimens (DTRs), also known as treatment algorithms or adaptive interventions, play an increasingly important role in many health domains. DTRs are motivated to address the unique and changing needs of individuals by delivering the type of treatment needed, when needed, while minimizing unnecessary treatment.
arxiv
Adjusting for Partial Compliance in SMARTs: a Bayesian Semiparametric Approach [PDF]
arXiv, 2020 The cyclical and heterogeneous nature of many substance use disorders highlights the need to adapt the type or the dose of treatment to accommodate the specific and changing needs of individuals. The Adaptive Treatment for Alcohol and Cocaine Dependence study (ENGAGE) is a multi-stage randomized trial that aimed to provide longitudinal data for ...
arxiv
Platform Criminalism: The 'Last-Mile' Geography of the Darknet Market Supply Chain [PDF]
, 2017 Does recent growth of darknet markets signify a slow reorganisation of the illicit drug trade? Where are darknet markets situated in the global drug supply chain? In principle, these platforms allow producers to sell directly to end users, bypassing traditional trafficking routes.
arxiv +1 more source
American Journal of Psychiatry, 1978 The author reviews the literature on hallucinations that occur as a result of acute and chronic administration of cocaine. He examined the phenomenology of cocaine hallucinations in a group of 85 recreational cocaine users, 15 of whom reported hallucinatory experiences in visual, tactile, olfactory, auditory, and gustatory modalities.
openaire +2 more sources
Associations amongst form of cocaine used (powder vs crack vs both) and HIV-related outcomes
Addictive Behaviors Reports, 2021 Introduction: Cocaine (including powder and crack) use is common among people with HIV (PWH). We identified socio-demographic and behavioral factors associated with cocaine use (overall and various forms) among PWH; we also examined differences in HIV ...
Yiyang Liu +4 more
doaj
Frontiers in Behavioral Neuroscience, 2017 The reorientation away from drugs of abuse and toward social interaction is a highly desirable but as yet elusive goal in the therapy of substance dependence. We could previously show that cocaine preferring Sprague-Dawley rats which engaged in only four
Tanja Bregolin +3 more
doaj +1 more source
Bayesian Set of Best Dynamic Treatment Regimes and Sample Size Determination for SMARTs with Binary Outcomes [PDF]
arXiv, 2020 One of the main goals of sequential, multiple assignment, randomized trials (SMART) is to find the most efficacious design embedded dynamic treatment regimes. The analysis method known as multiple comparisons with the best (MCB) allows comparison between dynamic treatment regimes and identification of a set of optimal regimes in the frequentist setting
arxiv