Results 71 to 80 of about 346,320 (307)

Community sewage sensors towards evaluation of drug use trends: detection of cocaine in wastewater with DNA-directed immobilization aptamer sensors [PDF]

, 2016
Illicit drug use has a global concern and effective monitoring and interventions are highly required to combat drug abuse. Wastewater-based epidemiology (WBE) is an innovative and cost-effective approach to evaluate community-wide drug use trends ...
Castrignanò, Erika, Estrela, Pedro, Frost, Christopher G., Kasprzyk-Hordern, Barbara, Yang, Zhugen   +4 more
core   +1 more source

The Effects of Excitatory and Inhibitory Social Cues on Cocaine-Seeking Behavior

Frontiers in Behavioral Neuroscience, 2016
Social partners influence the likelihood of using drugs, developing a substance use disorder, and relapse to drug use after a period of abstinence. Preclinical studies report that social cues influence the acquisition of cocaine use, the escalation of ...
Mark Andrew Smith, Huailin Zhang, Andrea Maureen Robinson   +2 more
doaj   +1 more source

Genetic and epigenetic analysis of the serotonin 2A receptor in the context of cocaine abuse

Epigenetics, 2022
Despite more than 2 million American cocaine users monthly, there is no approved drug for treating cocaine use disorder. Cocaine use disorder has a multifactorial aetiology, including both genetic and environmental factors.
Aysheh Alrfooh, Ryan M. Smith
doaj   +1 more source

Blunted Cystine–Glutamate Antiporter Function in the Nucleus Accumbens Promotes Cocaine-induced Drug Seeking [PDF]

, 2008
Repeated cocaine alters glutamate neurotransmission, in part, by reducing cystine–glutamate exchange via system xc−, which maintains glutamate levels and receptor stimulation in the extrasynaptic compartment.
Abdulhameed, Omer, Baker, David A., Grier, Mark D., Kau, Kristen S., Madayag, Aric, Mantsch, John R.   +5 more
core   +1 more source

Adolescent methylphenidate treatment differentially alters adult impulsivity and hyperactivity in the Spontaneously Hypertensive Rat model of ADHD [PDF]

, 2016
Impulsivity and hyperactivity are two facets of attention deficit/hyperactivity disorder (ADHD). Impulsivity is expressed as reduced response inhibition capacity, an executive control mechanism that prevents premature execution of an intermittently ...
Bardo, M. T., Dwoskin, L. P., Kantak, K. M., Somkuwar, S. S.   +3 more
core   +1 more source

Understanding Substance Use and Suicide Risk Among LGBTQ+ College Students Post‐COVID‐19

Journal of Addictions &Offender Counseling, EarlyView.
ABSTRACT This study examines the reported frequency of substance use, levels of suicide risk, and their relationships among LGBTQ+ college students (N = 192) following the COVID‐19 pandemic. Participants most commonly reported alcohol and marijuana use, and least commonly reported unprescribed prescription opioid or heroin use.
Afroze N. Shaikh, Jordan B. Westcott, Brittney N. R. Irion, Jackie Yang, Illiana R. Navarra‐Bueno, Hannah Martinson, Noah Diaz   +6 more
wiley   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

A latent class analysis of the past-30-day substance use patterns among lifetime cocaine users: Findings from a community sample in North Central Florida

Addictive Behaviors Reports, 2019
Objectives: Cocaine use is increasing and many cocaine users engage in polysubstance use. Within polysubstance use, relationships among use of individual substances are necessarily complex.
Yiyang Liu, Amy L. Elliott, Mirsada Serdarevic, Robert F. Leeman, Linda B. Cottler   +4 more
doaj   +1 more source

Ibrutinib as a potential therapeutic for cocaine use disorder

Translational Psychiatry, 2021
Cocaine use presents a worldwide public health problem with high socioeconomic cost. No current pharmacologic treatments are available for cocaine use disorder (CUD) or cocaine toxicity.
Spencer B. Huggett, Jeffrey S. Hatfield, Joshua D. Walters, John E. McGeary, Justine W. Welsh, Trudy F. C. Mackay, Robert R. H. Anholt, Rohan H. C. Palmer   +7 more
doaj   +1 more source

Decision‐making and risk‐taking as predictors of health risk behaviors in the Millennium Cohort Study

JCPP Advances, EarlyView.
Abstract Background Facets of decision‐making and risk‐taking are implicated in adolescent health risk behaviors; however, whether they may lead to adolescent engagement in substance use, gambling, and self‐harm is unknown. Methods We used the Millennium Cohort Study to test whether a task‐based measure of decision‐making and risk‐taking predicts ...
Nicole G. Hammond, Georgia Condran, Elise E. DeVito, Marie‐Claude Geoffroy, Ian Colman   +4 more
wiley   +1 more source