Results 71 to 80 of about 66,419 (330)
Cochlea-inspired tonotopic resonators
Materials & Design, 2023 The cochlea has long been the subject of investigation in various research fields due to its intriguing spiral architecture and unique sensing characteristics. One of its most interesting features is tonotopy, the ability to sense acoustic waves at different spatial locations based on their frequency content. In this work, we propose a novel design for
Vinícius F. Dal Poggetto +6 more
openaire +4 more sources
Advanced Science, EarlyView.D‐galactose (D‐gal) induced inner ear hair cell senescence by inhibiting TFEB transcription. RONIN/HCF1 promotes TFEB transcription to prevent cochlear HCs from D‐gal‐induced senescence through autophagy activation. Abstract Age‐related hearing loss is characterized by senescent inner ear hair cells (HCs) and reduced autophagy.
Yongjie Wei +18 more
wiley +1 more source
European Journal of Histochemistry, 2017 Kölliker’s organ is a temporary but indispensable structure in the development of the cochlea. Supporting cells (SCs) within it release adenosine 5’-triphosphate (ATP), which may play a crucial role in cochlear development before the onset of hearing. To
Jun Liu +3 more
doaj +1 more source
The effects of hyperinsulinemia on cochlear functions
Noise and Health, 2020 Context: Hyperinsulinemia is the most common metabolic change associated with cochleovestibular diseases. Aim: We aimed to investigate the auditory functions in hyperinsulinemic individuals.
Arzu Or Koca +2 more
doaj +1 more source
Frontiers in Neurology, 2022 In the post-natal mouse cochlea, type II spiral ganglion neurons (SGNs) innervating the electromotile outer hair cells (OHCs) of the ‘cochlear amplifier' selectively express the type III intermediate filament peripherin gene (Prph). Immunolabeling showed
Jennie M. E. Cederholm +11 more
doaj +1 more source
The cochlea in skull base surgery: an anatomy study.
Journal of Neurosurgery, 2016 OBJECTIVE The object of this study was to examine the relationships of the cochlea as a guide for avoiding both cochlear damage with loss of hearing in middle fossa approaches and injury to adjacent structures in approaches directed through the cochlea ...
Jian Wang +5 more
semanticscholar +1 more source
Advanced Science, EarlyView.Current preclinical studies of AAV‐mediated gene therapy explore different strategies based on the characteristics of inner ear diseases. For genetic hearing loss, approaches include the replacement of a “good gene,” removal of a “bad gene,” or direct correction of mutations through base editing.
Fan Wu +7 more
wiley +1 more source
Vulnerable frequency as an independent prognostic factor for sudden sensorineural hearing loss
Frontiers in Neurology, 2022 ObjectivesSudden sensorineural hearing loss (SSNHL) is a common otology emergency in the practice. Its severe hearing impairment and prognosis impair the quality of life.
Chaoqun Liang +9 more
doaj +1 more source
Advanced Science, EarlyView.Pinoresinol diglucoside, a bioactive component extracted from traditional Chinese medicine, attenuates cisplatin‐induced ototoxicity in vivo and in vitro. The protective effect is achieved by downregulation of Socs1. The present study is the first to investigate the expression and function of Socs1 in inner ear, which is known to promote ferroptosis ...
Yin Chen +12 more
wiley +1 more source
Effect of Auditory Predictability on the Human Peripheral Auditory System
Frontiers in Neuroscience, 2020 Auditory perception is facilitated by prior knowledge about the statistics of the acoustic environment. Predictions about upcoming auditory stimuli are processed at various stages along the human auditory pathway, including the cortex and midbrain ...
Lars Riecke +3 more
doaj +1 more source