Results 31 to 40 of about 16,526 (214)

Energetic Cocrystals – Structural Studies of Nitrotriazolone Salts & Cocrystals [PDF]

open access: yesActa Crystallographica Section A Foundations and Advances, 2014
Developments in energetic materials are currently focused on the requirements for safer, yet still powerful materials for uses within mining, munitions and rocket propulsion systems One strategy that can be used to achieve these desirable properties is to synthesise new molecules, but this is both time-consuming and resource-intensive. Instead, another
Hayleigh Lloyd   +5 more
openaire   +1 more source

Recent Advances in Pharmaceutical Cocrystals: A Focused Review of Flavonoid Cocrystals

open access: yesMolecules, 2023
Cocrystallization is currently an attractive technique for tailoring the physicochemical properties of active pharmaceutical ingredients (APIs). Flavonoids are a large class of natural products with a wide range of beneficial properties, including anticancer, anti-inflammatory, antiviral and antioxidant properties, which makes them extensively studied.
Jia Xu   +6 more
openaire   +3 more sources

Reversible Luminescent Switching in an Organic Cocrystal: Multi‐Stimuli‐Induced Crystal‐to‐Crystal Phase Transformation

open access: yesAngewandte Chemie, 2020
A luminescent cocrystal system is reported to undergo crystal-to-crystal phase transformation from yellow-emitting polymorph I to green-emitting polymorph II, triggered by THF fuming or heating, and the green emission can recover to the initial yellow ...
Yingjie Liu   +6 more
semanticscholar   +1 more source

Virtual Cocrystal Screening Methods as Tools to Understand the Formation of Pharmaceutical Cocrystals—A Case Study of Linezolid, a Wide-Range Antibacterial Drug

open access: yes, 2021
Experimental mechanochemical screening of cocrystals with linezolid (LIN) resulted in the formation of six new crystal phases, including three neat cocrystals and three cocrystal hydrates, in addit...
Mehrnaz Khalaji   +2 more
semanticscholar   +1 more source

Pharmaceutical Cocrystals

open access: yesProcedia Chemistry, 2014
AbstractCocrystals are very interesting and useful product. In this paper the main information about cocrystals is presented. It is shown that cocrystals are solid substances, which consist of few components mixed together. There are a lot of ways of cocrystals production and application.
Korotkova, Elena Ivanovna   +1 more
openaire   +2 more sources

Preparation and Characterization of Carbamazepine Cocrystal in Polymer Solution

open access: yesPharmaceutics, 2017
In this study, we attempted to prepare carbamazepine (CBZ) cocrystal through the solution method in ethanol-water solvent mixture (volume ratio 1:1) and polyvinyl pyrrolidone (PVP) solution.
Hao Zhang   +4 more
doaj   +1 more source

Urea as a Cocrystal Former—Study of 3 Urea Based Pharmaceutical Cocrystals [PDF]

open access: yesPharmaceutics, 2021
Cocrystallization is commonly used for its ability to improve the physical properties of APIs, such as solubility, bioavailability, compressibility, etc. The pharmaceutical industry is particularly interested in those cocrystals comprising a GRAS former in connection with the target API.
Fucheng Leng, Koen Robeyns, Tom Leyssens
openaire   +4 more sources

Raman and Terahertz Spectroscopic Investigation of Cocrystal Formation Involving Antibiotic Nitrofurantoin Drug and Coformer 4-aminobenzoic Acid

open access: yesCrystals, 2016
Cocrystallization could improve most physicochemical properties of specific active pharmaceutical ingredients, which has great potential in pharmaceutical development.
Yong Du, Qiang Cai, Jiadan Xue, Qi Zhang
doaj   +1 more source

Liquid-Assisted Grinding to Prepare a Cocrystal of Adefovir Dipivoxil Thermodynamically Less Stable than Its Neat Phase

open access: yesCrystals, 2015
Liquid-assisted grinding was employed to generate a cocrystal of adefovir dipivoxil (AD) and glutaric acid (GLU), which had not been successfully obtained through solution crystallization.
Sungyup Jung, Insil Choi, Il Won Kim
doaj   +1 more source

Progress in Research on Artificial Intelligence Applied to Polymorphism and Cocrystal Prediction

open access: yesACS Omega, 2021
Artificial intelligence (AI) is a technology that builds an artificial system with certain intelligence and uses computer software and hardware to simulate intelligent human behavior.
Tianyu Heng   +5 more
semanticscholar   +1 more source

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