Results 11 to 20 of about 14,340 (184)

Preparation and Characterization of Carbamazepine Cocrystal in Polymer Solution

Pharmaceutics, 2017
In this study, we attempted to prepare carbamazepine (CBZ) cocrystal through the solution method in ethanol-water solvent mixture (volume ratio 1:1) and polyvinyl pyrrolidone (PVP) solution.
Hao Zhang, Ying Zhu, Ning Qiao, Yang Chen, Linghuan Gao   +4 more
doaj   +2 more sources

Poling-Polarization-Mediated Centrosymmetric Charge-Transfer Organic-Cocrystal-Based Flexible Triboelectric Nanogenerator

, 2022
In the present study, charge transfer (CT) organic cocrystals, with suitable organic donors (D) and acceptors (A), have been synthesized and utilized in the fabrication of a flexible triboelectric nanogenerator (TENG) to harvest mechanical energy.
Koushik Mandal (13002548), Rohit Bhowal (6175355), Avanish Kumar Srivastava (1760779), Simadri Badatya (10930577), Manoj Kumar Gupta (131337), Deepak Chopra (328612)   +5 more
core   +3 more sources

Cocrystal Prediction by Artificial Neural Networks [PDF]

, 2020
A significant amount of attention has been given to the design and synthesis of cocrystals by both industry and academia because of its potential to change a molecule’s physicochemical properties.
Elias, Vlieg, Paul, Tinnemans, Jan-Joris, Devogelaer, Hugo, Meekes, Rene, de Gelder   +4 more
core   +2 more sources

Caffeine and 4-Hydroxybenzoic Acid Cocrystal Hydrate: Preparation, Characterization, and Evaluation. [PDF]

Chemphyschem
A 1:1:1 hydrate of caffeine (CAF) and 4‐hydroxybenzoic acid (4HBA) was crystallized to modulate drug performance. Structural analysis reveals enhanced intermolecular interactions, while dissolution studies show controlled release in gastric and rapid release in intestinal conditions.
Gogna S, Du JJ, Groundwater PW, Fares M, Kwok PCL, Yau GTY, Alffenaar JC, Hibbs DE.   +7 more
europepmc   +2 more sources

A Novel, Extremely Bioavailable Cocrystal of Pterostilbene [PDF]

, 2022
New multicomponent solid forms of the nutraceutical pterostilbene have been discovered and characterized through experimental cocrystal screening.
Barbas Cañero, Rafael, Font Bardia, Ma. Mercedes, Bofill, Lídia, Ràfols Llach, Clara, Prohens López, Rafael, Sande, Dafne de, Albertí, Joan   +6 more
core   +1 more source

Halogen Bonding to the Azulene Pi-System: Cocrystal Design of Pleochroism [PDF]

, 2020
We describe the rational development of a design to create pleochroic molecular solids, by using C-I...pi halogen bonds to pre-organise different types of chromophores in a cocrystal.
Jogirdas, Vainauskas, Filip, Topic, Christopher J., Barrett, Tomislav, Friscic, Oleksandr S., Bushuyev   +4 more
core   +2 more sources

Impact of cocrystal solution-state stability on cocrystal dissociation and polymorphic drug recrystallization during dissolution

, 2021
The present study aimed to investigate how cocrystal solution-state stability may affect the polymorphic drug formation and transition during dissolution.
Lakerveld, R, Tong, HHY, Wong, KC, Chow, SF, Chen, R, Lo, PS, XUAN, B, Chen, YCS   +7 more
core   +1 more source

Liquid-Assisted Grinding to Prepare a Cocrystal of Adefovir Dipivoxil Thermodynamically Less Stable than Its Neat Phase

Crystals, 2015
Liquid-assisted grinding was employed to generate a cocrystal of adefovir dipivoxil (AD) and glutaric acid (GLU), which had not been successfully obtained through solution crystallization.
Sungyup Jung, Insil Choi, Il Won Kim
doaj   +1 more source

Cocrystal Trimorphism as a Consequence of Orthogonality of Halogen- and Hydrogen-Bonding [PDF]

, 2019
True trimorphic cocrystals, i.e. multi-component molecular crystals of identical composition that exhibit three polymorphic structures, are exceedingly rare and so far no halogen-bonded cocrystal system was reported to exhibit trimorphism.
Dominik, Cincic, Filip, Topic, Katarina, Lisac, Mihails, Arhangelskis, Kari, Rissanen, Tomislav, Friscic   +5 more
core   +2 more sources

Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

Pharmaceutics, 2011
Cocrystal formation rates during dry grinding and liquid-assisted grinding were investigated by X-ray powder diffractometry and Raman spectroscopy. Two polymorphic forms of piracetam were used to prepare known piracetam cocrystals as model substances, i ...
Keith Gordon, Thomas Rades, Claudia S. Leopold, Clare J. Strachan, Marten Klukkert, Albrecht Sakmann, Korbinian A. M. Löbmann, Sönke Rehder   +7 more
doaj   +1 more source