Results 21 to 30 of about 14,800 (170)

Cocrystal Prediction by Artificial Neural Networks [PDF]

open access: yes, 2020
A significant amount of attention has been given to the design and synthesis of cocrystals by both industry and academia because of its potential to change a molecule’s physicochemical properties.
Elias, Vlieg   +4 more
core   +2 more sources

Cocrystals Enhance Biopharmaceutical and Antimicrobial Properties of Norfloxacin

open access: yesPharmaceutics, 2023
A solvate cocrystal of the antimicrobial norfloxacin (NFX) was formed by using isonicotinamide (INA) as a coformer with the solvent evaporation technique. The cocrystal formation was confirmed by performing solid-state characterization techniques.
Samantha Nascimento Gomes   +6 more
doaj   +1 more source

Morphology and properties of CL-20/MTNP cocrystal prepared via facile spray drying

open access: yesFirePhysChem, 2023
Cocrystal of 2,4,6,8,10,12-hexaazaisowurtzitane/1-methyl-3,4,5-trinitropyrazole (CL-20/MTNP) in a 1:1 molar ratio is a promising energetic material, since it combines the superior detonation performance of CL-20 and good mechanical sensitivity of MTNP ...
Xueyan Zhao   +4 more
doaj   +1 more source

Halogen Bonding to the Azulene Pi-System: Cocrystal Design of Pleochroism [PDF]

open access: yes, 2020
We describe the rational development of a design to create pleochroic molecular solids, by using C-I...pi halogen bonds to pre-organise different types of chromophores in a cocrystal.
Jogirdas, Vainauskas   +4 more
core   +2 more sources

Color-Tunable Upconversion-Emission Switch Based on Cocrystal-to-Cocrystal Transformation

open access: yes, 2023
Cocrystal engineering, involving the assembly of two or more components into a highly ordered solid-state superstructure, has emerged as a popular strategy for tuning the photophysical properties of crystalline materials.
Huang Wu   +13 more
core   +2 more sources

Mechanochemical Synthesis of the Catechol-Theophylline Cocrystal: Spectroscopic Characterization and Molecular Structure

open access: yesApplied Sciences, 2021
Pharmaceutical cocrystallization offers the possibility to modify the physicochemical and biopharmaceutical properties of active pharmaceutical ingredients.
Juan Saulo González-González   +4 more
doaj   +1 more source

Karakterisasi Cocrystal Glibenklamida Dengan Variasi Pelarut dan Uji Stabilitas Termal

open access: yesJPSCR: Journal of Pharmaceutical Science and Clinical Research, 2022
Glibenklamida termasuk dalam Biopharmaceutical Classification System (BCS) kelas II yaitu kelarutannya rendah. Kelarutan dapat ditingkatkan dengan dengan mengubah glibenklamida menjadi bentuk cocrystal.
Anang Kuncoro Rachmad Setiawan   +2 more
doaj   +1 more source

Liquid-Assisted Grinding to Prepare a Cocrystal of Adefovir Dipivoxil Thermodynamically Less Stable than Its Neat Phase

open access: yesCrystals, 2015
Liquid-assisted grinding was employed to generate a cocrystal of adefovir dipivoxil (AD) and glutaric acid (GLU), which had not been successfully obtained through solution crystallization.
Sungyup Jung, Insil Choi, Il Won Kim
doaj   +1 more source

Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

open access: yesPharmaceutics, 2011
Cocrystal formation rates during dry grinding and liquid-assisted grinding were investigated by X-ray powder diffractometry and Raman spectroscopy. Two polymorphic forms of piracetam were used to prepare known piracetam cocrystals as model substances, i ...
Keith Gordon   +7 more
doaj   +1 more source

Hypergolic Triggers as Cocrystal Formers: Cocrystallization for Creating New Hypergolic Materials with Tunable Energy Content [PDF]

open access: yes, 2019
We demonstrate a cocrystal-based strategy to create new solid hypergols, i.e. materials exhibiting spontaneous ignition in contact with an oxidant, in which the energy content and density of the material can be changed without affecting the ignition ...
Giovanni, Rachiero   +4 more
core   +2 more sources

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