Results 21 to 30 of about 14,340 (184)

Raman and Terahertz Spectroscopic Investigation of Cocrystal Formation Involving Antibiotic Nitrofurantoin Drug and Coformer 4-aminobenzoic Acid

Crystals, 2016
Cocrystallization could improve most physicochemical properties of specific active pharmaceutical ingredients, which has great potential in pharmaceutical development.
Yong Du, Qiang Cai, Jiadan Xue, Qi Zhang
doaj   +1 more source

Theoretical predict structure and property of the novel CL-20/2,4-DNI cocrystal by systematic search approach

Defence Technology, 2022
Cocrystallization integrates the merits of high energy and insensitivity between energetic molecules to obtain energetics with satisfying performance. However, how to obtain supramolecular synthons accurately and rapidly for predicting the structure and ...
Hao-jie Li, Jian-chao Liu, Li Yang, Zhen-zhan Yan, Yue-wen Lu, Ji-min Han, Xiao-ting Ren, Wei Li   +7 more
doaj   +1 more source

Influence of Sodium Lauryl Sulfate and Tween 80 on Carbamazepine–Nicotinamide Cocrystal Solubility and Dissolution Behaviour

Pharmaceutics, 2013
The influence of the surfactants of sodium lauryl sulfate (SLS) and Tween 80 on carbamazepine–nicotinamide (CBZ–NIC) cocrystal solubility and dissolution behaviour has been studied in this work.
Ke Wang, Ning Qiao, Mingzhong Li
doaj   +1 more source

Hypergolic Triggers as Cocrystal Formers: Cocrystallization for Creating New Hypergolic Materials with Tunable Energy Content [PDF]

, 2019
We demonstrate a cocrystal-based strategy to create new solid hypergols, i.e. materials exhibiting spontaneous ignition in contact with an oxidant, in which the energy content and density of the material can be changed without affecting the ignition ...
Giovanni, Rachiero, Hatem M., Titi, Mihails, Arhangelskis, Tomislav, Friscic, Robin, Rogers   +4 more
core   +2 more sources

The Cocrystal of Ubiquinol: Improved Stability and Bioavailability

Pharmaceutics, 2023
Coenzyme Q10 (CoQ10) exists in two forms, an oxidized form and a reduced form. Ubiquinol is the fully reduced form of CoQ10. Compared to the oxidized form, ubiquinol has a much higher biological absorption and better therapeutic effect.
Qi Zhang, Mengyuan Xia, Chenxuan Zheng, Yinghong Yang, Junjie Bao, Wenjuan Dai, Xuefeng Mei   +6 more
doaj   +1 more source

Short Sb···Sb Contacts in Polymorphic Tris(p‐Tolyl)Antimony: A Hallmark of Organoantimony(III) Solid‐State Chemistry?

Angewandte Chemie, EarlyView.
Discovery of polymorphism in solid tris(p‐tolyl)antimony(III) highlighted short, direct antimony‐antimony contacts, with interatomic separation shorter than the sum of the van der Waals radii, and calculated interaction energy of ca. 26 kJ mol−1 that includes a significant dispersion component.
Imogen Suh, Michael Ferguson, Filip Topić, Fu‐Qiang Gong, Mihails Arhangelskis, Hatem M. Titi, D. Scott Bohle, Vinko Nemec, Levente Kiss, Andrew J. Morris, Cristian Silvestru, Dominik Cinčić, Tomislav Friščić   +12 more
wiley   +2 more sources

Synthesis, Characterization and Morphological Study of Nicotinamide and p-Coumaric Acid Cocrystal

Indonesian Journal of Chemistry, 2020
Cocrystallization is one of the potent methods used to modify the physicochemical properties of drugs. Cocrystal of nicotinamide (NIC):p-coumaric acid (COU) was synthesized by a slow evaporation method using acetonitrile.
Mohamad Nor Amirul Azhar Kamis, Hamizah Mohd Zaki, Nornizar Anuar, Mohammad Noor Jalil   +3 more
doaj   +1 more source

Continuous Manufacturing of Cocrystals Using 3D-Printed Microfluidic Chips Coupled with Spray Coating

Pharmaceuticals, 2023
Using cocrystals has emerged as a promising strategy to improve the physicochemical properties of active pharmaceutical ingredients (APIs) by forming a new crystalline phase from two or more components.
Aytug Kara, Dinesh Kumar, Anne Marie Healy, Aikaterini Lalatsa, Dolores R. Serrano   +4 more
doaj   +1 more source

Cocrystal construction between the ethyl ester with parent drug of diclofenac: structural, stability, and anti-inflammatory study

Heliyon, 2019
This study aimed to collect the crystallographic data of ethyl diclofenac and discover a cocrystal from this ester with its parent, diclofenac acid, and to investigate their physicochemical properties and anti-inflammation activity.
Ilma Nugrahani, Dwi Utami, Yuda Prasetya Nugraha, Hidehiro Uekusa, Rahel Hasianna, Aisyah Amalia Darusman   +5 more
doaj   +1 more source

Molecular dynamics application of cocrystal energetic materials: A review

Nanotechnology Reviews, 2022
Cocrystallization is an important method to obtain high-energy and low-sensitivity explosives. Therefore, the synthesis, structures, and properties of cocrystal energetic materials have become a highly active research topic.
Wang Fuping, Du Guangyan, Liu Xinchi, Shao Mingyu, Zhang Chenggen, Chen Lang   +5 more
doaj   +1 more source