Results 21 to 30 of about 8,500 (189)
Recent Advances in Pharmaceutical Cocrystals: A Focused Review of Flavonoid Cocrystals
Molecules, 2023 Cocrystallization is currently an attractive technique for tailoring the physicochemical properties of active pharmaceutical ingredients (APIs). Flavonoids are a large class of natural products with a wide range of beneficial properties, including anticancer, anti-inflammatory, antiviral and antioxidant properties, which makes them extensively studied.
Jia Xu +6 more
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Morphology and properties of CL-20/MTNP cocrystal prepared via facile spray drying
FirePhysChem, 2023 Cocrystal of 2,4,6,8,10,12-hexaazaisowurtzitane/1-methyl-3,4,5-trinitropyrazole (CL-20/MTNP) in a 1:1 molar ratio is a promising energetic material, since it combines the superior detonation performance of CL-20 and good mechanical sensitivity of MTNP ...
Xueyan Zhao +4 more
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Structure and intermolecular interactions of the rare amide-pyridine synthon: a cocrystal of nicotinamide and 2-chloro-3-hydroxypyridine. [PDF]
Acta Crystallogr C Struct ChemConsidering its low occurrence in the Cambridge Structural Database, is the amide–pyridyl synthon easy to form, and what structural factors affects its interaction energy and its subsequent formation?Nicotinamide (Nico) and derivatives of pyridine are important materials in both the pharmaceutical and agrochemical industries.
Akerele O, Lemmerer A.
europepmc +2 more sources
Creating Cocrystals: A Review of Pharmaceutical Cocrystal Preparation Routes and Applications [PDF]
Crystal Growth & Design, 2018 peer ...
Maryam Karimi-Jafari +3 more
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Brazilian Journal of Pharmaceutical Sciences, 2023 In this study, we investigated the effects of polymers on the pharmaceutical cocrystal formation process. Ibuprofen (IBU) was selected as the active pharmaceutical ingredient (API), nicotinamide (NIC) and saccharin (SAC) as the cocrystal coformer (CCF ...
Xintong Yang, Yang Chen, Ning Qiao
doaj +1 more source
Applied Sciences, 2021 Pharmaceutical cocrystallization offers the possibility to modify the physicochemical and biopharmaceutical properties of active pharmaceutical ingredients.
Juan Saulo González-González +4 more
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Formation of Ketoprofen-Malonic Acid Cocrystal by Solvent Evaporation Method
Indonesian Journal of Chemistry, 2017 The purpose of this work was to explore the formation of ketoprofen-malonic acid cocrystal by solvent evaporation method. Early detection of cocrystal formation was conducted by hot stage microscopy and solid-liquid phase diagram. Cocrystal were prepared
Yudi Wicaksono +2 more
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Karakterisasi Cocrystal Glibenklamida Dengan Variasi Pelarut dan Uji Stabilitas Termal
JPSCR: Journal of Pharmaceutical Science and Clinical Research, 2022 Glibenklamida termasuk dalam Biopharmaceutical Classification System (BCS) kelas II yaitu kelarutannya rendah. Kelarutan dapat ditingkatkan dengan dengan mengubah glibenklamida menjadi bentuk cocrystal.
Anang Kuncoro Rachmad Setiawan +2 more
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Preparation and Characterization of Carbamazepine Cocrystal in Polymer Solution
Pharmaceutics, 2017 In this study, we attempted to prepare carbamazepine (CBZ) cocrystal through the solution method in ethanol-water solvent mixture (volume ratio 1:1) and polyvinyl pyrrolidone (PVP) solution.
Hao Zhang +4 more
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Crystals, 2015 Liquid-assisted grinding was employed to generate a cocrystal of adefovir dipivoxil (AD) and glutaric acid (GLU), which had not been successfully obtained through solution crystallization.
Sungyup Jung, Insil Choi, Il Won Kim
doaj +1 more source