Results 31 to 40 of about 14,340 (184)

Helical Single Crystals of Porous Hydrogen‐Bonded Organic Frameworks as a Candidate for Morphologically Functional Organic Materials

open access: yesAngewandte Chemie, EarlyView.
Helical‐shaped crystals of a hydrogen‐bonded organic framework (HOF) with permanent porosity have been developed. The helical HOF shows expansion and contraction, respectively, upon desorption and adsorption of solvents. Moreover, doping of additive molecules can modulate the photophysical properties and morphology of the helical HOF, showing the ...
Yuzuki Murata   +11 more
wiley   +2 more sources

Combining a Drug and a Nutraceutical: A New Cocrystal of Praziquantel and Curcumin

open access: yesCrystals
This study explores the co-crystallization between the drug praziquantel (PZQ) and the nutraceutical curcumin (CU). The investigation revealed two novel solid forms: a cocrystal solvate with ethyl acetate and a non-solvated cocrystal.
Camila Caro Garrido   +5 more
doaj   +1 more source

Crystal Structure, Solubility, and Pharmacokinetic Study on a Hesperetin Cocrystal with Piperine as Coformer

open access: yesPharmaceutics, 2022
Hesperetin (HES) is a key biological active ingredient in citrus peels, and is one of the natural flavonoids that attract the attention of researchers due to its numerous therapeutic bioactivities that have been identified in vitro.
Yanjie Liu   +5 more
doaj   +1 more source

Improved Manufacturability and In Vivo Comparative Pharmacokinetics of Dapagliflozin Cocrystals in Beagle Dogs and Human Volunteers

open access: yesPharmaceutics, 2021
Dapagliflozin (DAP), which improves glycemic control in patients with type 2 diabetes mellitus, has poor physical properties against heat and moisture, thus hindering its manufacturing potential.
Sangho Cho   +5 more
doaj   +1 more source

RS, S (+) - and R (−)-ibuprofen cocrystal polymorphs: Vibrational spectra, XRD measurement and DFT calculation studies

open access: yesHeliyon
In this paper, cocrystal polymorphs of RS-ibuprofen (RS-IBU), S (+)-ibuprofen (S(+)-IBU), R (−)-ibuprofen (R(−)-IBU) with nicotinamide (NIC) were synthesized by different methods. RS-IBU is a chiral drug with only one chiral center in the molecule, which
Yaqi Jing   +7 more
doaj   +1 more source

Theoretical study of BTF/TNA cocrystal: Effects of hydrostatic pressure and temperature

open access: yesDefence Technology, 2015
Cocrystallization is a promising technique for the design and preparation of new explosives, and the stability of cocrystal is highly concerned by the researchers.
Peng-yuan Chen   +3 more
doaj   +1 more source

Synthesis and Characterization of a New Norfloxacin/Resorcinol Cocrystal with Enhanced Solubility and Dissolution Profile

open access: yesPharmaceutics, 2021
A new cocrystal of Norfloxacin, a poorly soluble fluoroquinolone antibiotic, has been synthetized by a solvent-mediated transformation experiment in toluene, using resorcinol as a coformer. The new cocrystal exists in both anhydrous and monohydrate forms
Hanan Fael   +4 more
doaj   +1 more source

A Spironolactone−Saccharin 1:1 Cocrystal Hemihydrate

open access: yes, 2016
We investigated the structures of the hydrated and dehydrated states and the in vitro dissolution of a spironolactone−saccharin 1:1 cocrystal hemihydrate, the cocrystal hydrate of a nonionizable, poorly water-soluble drug with a pharmaceutically ...
Hidehiro Uekusa (1441441)   +4 more
core   +2 more sources

Polyphenol‐Inspired Materials for Agricultural Applications

open access: yesAdvanced Materials, EarlyView.
This review outlines the use of polyphenol‐inspired materials for sustainable agriculture, highlighting their molecular design, interfacial assembly, structure–property relationships, and prospects toward precision agriculture, climate resilience, ecosystem protection, and circular bioeconomy strategies.
Haofu Liu   +8 more
wiley   +1 more source

Mechanochemical Synthesis of Pharmaceutical Cocrystal Suspensions via Hot Melt Extrusion: Enhancing Cocrystal Yield [PDF]

open access: yes, 2017
Pharmaceutical cocrystals have attracted increasing attention over the past decade as an alternative way to modify the physicochemical properties and hence improve the bioavailability of a drug, without sacrificing thermodynamic stability.
David S. Jones   +11 more
core   +1 more source

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