Results 41 to 50 of about 16,526 (214)
Uracil Derivatives for Halogen-Bonded Cocrystals [PDF]
International Journal of Molecular Sciences, 2021 Among non-covalent interactions, halogen bonding is emerging as a new powerful tool for supramolecular self-assembly. Here, along with a green and effective method, we report three new halogen-bonded cocrystals containing uracil derivatives and 1,2,4,5-tetrafluoro-3,6-diiodobenzene as X-bond donor coformer.
Mónica Benito +4 more
openaire +4 more sources
Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding
Pharmaceutics, 2011 Cocrystal formation rates during dry grinding and liquid-assisted grinding were investigated by X-ray powder diffractometry and Raman spectroscopy. Two polymorphic forms of piracetam were used to prepare known piracetam cocrystals as model substances, i ...
Keith Gordon +7 more
doaj +1 more source
Defence Technology, 2022 Cocrystallization integrates the merits of high energy and insensitivity between energetic molecules to obtain energetics with satisfying performance. However, how to obtain supramolecular synthons accurately and rapidly for predicting the structure and ...
Hao-jie Li +7 more
doaj +1 more source
Celecoxib cocrystal polymorphs† [PDF]
Acta Crystallographica Section A Foundations and Advances, 2014 Celecoxib (CEL) is a well-known nonsteroidal anti-inflammatory drug (NSAID) and selectively used from the cocxib family. It is a specific COX-2 inhibitor for pain and inflammation without inhibiting COX-1. A major downside of this popular NSAID is its poor aqueous solubility (9 mg L–1), which limits bioavailability (40%). Several methods were attempted
Geetha Bolla +2 more
openaire +1 more source
Solution Cocrystallization: A Scalable Approach for Cocrystal Production
Crystals, 2021 With an increasing interest in cocrystals due to various advantages, demand for large-scale cocrystallization techniques is rising. Solution cocrystallization is a solvent-based approach that utilizes several single-component crystallization concepts as ...
Nitin J Pawar +3 more
semanticscholar +1 more source
A Drug-Drug Cocrystal of Dihydromyricetin and Pentoxifylline.
Journal of Pharmacy and Science, 2021 Drug-drug cocrystals, which can regulate physicochemical properties of individual drugs and might produce synergistic therapeutic effects, have drawn growing interest in the pharmaceutical industry.
Lei Liu +4 more
semanticscholar +1 more source
Angewandte Chemie, EarlyView.Photoexcitation of an intramolecular charge‐transfer molecule doped into single crystals of a structurally similar host molecule results in well‐ordered, spectrally addressable, and orientation‐tunable triplet excitons that maintain coherence at elevated temperatures.
Yaoyao Han +6 more
wiley +2 more sources
Pharmaceutics, 2013 The influence of the surfactants of sodium lauryl sulfate (SLS) and Tween 80 on carbamazepine–nicotinamide (CBZ–NIC) cocrystal solubility and dissolution behaviour has been studied in this work.
Ke Wang, Ning Qiao, Mingzhong Li
doaj +1 more source
Synthesis, Characterization and Morphological Study of Nicotinamide and p-Coumaric Acid Cocrystal
Indonesian Journal of Chemistry, 2020 Cocrystallization is one of the potent methods used to modify the physicochemical properties of drugs. Cocrystal of nicotinamide (NIC):p-coumaric acid (COU) was synthesized by a slow evaporation method using acetonitrile.
Mohamad Nor Amirul Azhar Kamis +3 more
doaj +1 more source
The Cocrystal of Ubiquinol: Improved Stability and Bioavailability
Pharmaceutics, 2023 Coenzyme Q10 (CoQ10) exists in two forms, an oxidized form and a reduced form. Ubiquinol is the fully reduced form of CoQ10. Compared to the oxidized form, ubiquinol has a much higher biological absorption and better therapeutic effect.
Qi Zhang +6 more
doaj +1 more source