Results 41 to 50 of about 23,789 (261)
Process monitoring and visualization solutions for hot-melt extrusion : a review [PDF]
, 2013 Objectives: Hot-melt extrusion (HME) is applied as a continuous pharmaceutical manufacturing process for the production of a variety of dosage forms and formulations.
De Beer, Thomas +3 more
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Pharmaceutics, 2022 Hesperetin (HES) is a key biological active ingredient in citrus peels, and is one of the natural flavonoids that attract the attention of researchers due to its numerous therapeutic bioactivities that have been identified in vitro.
Yanjie Liu +5 more
doaj +1 more source
The co-crystal of TNT/CL-20 leads to decreased sensitivity toward thermal decomposition from first principles based reactive molecular dynamics [PDF]
, 2015 To gain an atomistic-level understanding of the experimental observation that the cocrystal TNT/CL-20 leads to decreased sensitivity, we carried out reactive molecular dynamics (RMD) simulations using the ReaxFF reactive force field.
An, Qi +5 more
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Introductory lecture: Mechanochemistry, a versatile synthesis strategy for new materials. [PDF]
, 2014 Mechanochemistry deals with reactions induced by the input of mechanical energy - for example by impacts within a vibratory ball mill. The technique has a long history with significant contributions from Ostwald, Carey Lea and, notably, Faraday ...
Eddleston, Mark D, Jones, William
core +1 more source
Pharmaceutics, 2013 The influence of the surfactants of sodium lauryl sulfate (SLS) and Tween 80 on carbamazepine–nicotinamide (CBZ–NIC) cocrystal solubility and dissolution behaviour has been studied in this work.
Ke Wang, Ning Qiao, Mingzhong Li
doaj +1 more source
The Cocrystal of Ubiquinol: Improved Stability and Bioavailability
Pharmaceutics, 2023 Coenzyme Q10 (CoQ10) exists in two forms, an oxidized form and a reduced form. Ubiquinol is the fully reduced form of CoQ10. Compared to the oxidized form, ubiquinol has a much higher biological absorption and better therapeutic effect.
Qi Zhang +6 more
doaj +1 more source
Cocrystal formation by Ionic liquid-assisted grinding: Case study with cocrystals of caffeine [PDF]
, 2018 iquid assisted grinding using imidazolium-based ionic liquids (IL-AG) was found to be effective in isolation of cocrystals and cocrystal polymorphs. Isolation of specific polymorphs of caffeine–citric acid (CAF–CA) and caffeine–glutaric acid (CAF–GLU ...
Meyerson, A. S. +2 more
core +1 more source
Pharmaceuticals, 2023 Using cocrystals has emerged as a promising strategy to improve the physicochemical properties of active pharmaceutical ingredients (APIs) by forming a new crystalline phase from two or more components.
Aytug Kara +4 more
doaj +1 more source
Interdependent interactions between TFIIB, TATA binding protein, and DNA. [PDF]
, 2002 Temperature-sensitive mutants of TFIIB that are defective for essential interactions were isolated. One mutation (G204D) results in disruption of a protein-protein contact between TFIIB and TATA binding protein (TBP), while the other (K272I) disrupts an ...
Buratowski, Robin M +2 more
core +2 more sources
Theoretical study of BTF/TNA cocrystal: Effects of hydrostatic pressure and temperature
Defence Technology, 2015 Cocrystallization is a promising technique for the design and preparation of new explosives, and the stability of cocrystal is highly concerned by the researchers.
Peng-yuan Chen +3 more
doaj +1 more source