Results 61 to 70 of about 14,800 (170)

Polymorphism of Carbamazepine Pharmaceutical Cocrystal: Structural Analysis and Solubility Performance

Pharmaceutics, 2023
Polymorphism is a common phenomenon among single- and multicomponent molecular crystals that has a significant impact on the contemporary drug development process. A new polymorphic form of the drug carbamazepine (CBZ) cocrystal with methylparaben (MePRB)
Artem O. Surov, Ksenia V. Drozd, Anna G. Ramazanova, Andrei V. Churakov, Anna V. Vologzhanina, Elizaveta S. Kulikova, German L. Perlovich   +6 more
doaj   +1 more source

Recent advances in chiral organic room‐temperature phosphorescence with circularly polarized luminescence

FlexMat, EarlyView.
This review systematically summarizes representative recent advances in organic circularly polarized room‐temperature phosphorescence materials toward optoelectronic and information security applications. Abstract Circularly polarized room‐temperature phosphorescence (CPRTP) materials combine the dual advantages of long‐lived triplet emission and ...
Liang Zhang, Ming‐Jun Ji, Chuan‐Feng Chen   +2 more
wiley   +1 more source

Two Cocrystal Polymorphs of Palmatine Chloride with Racemic Hesperetin

, 2021
Two polymorphic cocrystals of palmatine chloride with racemic hesperetin (Form I and Form II) have been prepared and investigated systematically. Crystal structure analysis reveals that reliable O-H···Cl– hydrogen-bonding interactions exist in both ...
Lei Liu, Yanguang Li, Quanhu Guo, Rongjian Sa (1561984), Benyong Lou, Mei Zhang, Quanhu Guo (11884377), Rongjian Sa, Benyong Lou (1693906), Lei Liu (5074), Yanjie Zhang, Yanguang Li (438869), Yanjie Zhang (360019), Mei Zhang (46138)   +13 more
core   +1 more source

Organic neuromorphic optoelectronic sensing materials, intelligent devices, and bionic systems

InfoMat, EarlyView.
Due to the excellent performance and biocompatibility, organic neuromorphic photoelectric sensing technology is regarded as a highly promising research field. In this review, Liu et al. summarize the recent advances in related materials, devices, and system integration.
Yu‐ang Liu, Guocai Liu, Lang Jiang, Yunqi Liu, Yunlong Guo   +4 more
wiley   +1 more source

Neutron Vibrational Spectroscopic Study of the Acetonitrile:Acetylene (1:2) Cocrystal Relevant to Titan, Saturn’s Moon [PDF]

Saturn’s moon Titan features a surface composed of various organic solids with pronounced compositional and structural diversity. On top of the icy core, the surface experiences temperature of ~93 K and pressure of ~1.45 atm. Under these conditions, most
Craig , Brown, Rafael, Balderas-Xicohtencatl, Yongqiang, Cheng, Tomce, Runcevski, Morgan , Kramer, Luke, Daemen, Anibal, Ramirez Cuesta   +6 more
core   +1 more source

Short Sb···Sb Contacts in Polymorphic Tris(p‐Tolyl)Antimony: A Hallmark of Organoantimony(III) Solid‐State Chemistry?

Angewandte Chemie, Volume 138, Issue 41, 5 October 2026.
Discovery of polymorphism in solid tris(p‐tolyl)antimony(III) highlighted short, direct antimony‐antimony contacts, with interatomic separation shorter than the sum of the van der Waals radii, and calculated interaction energy of ca. 26 kJ mol−1 that includes a significant dispersion component.
Imogen Suh, Michael Ferguson, Filip Topić, Fu‐Qiang Gong, Mihails Arhangelskis, Hatem M. Titi, D. Scott Bohle, Vinko Nemec, Levente Kiss, Andrew J. Morris, Cristian Silvestru, Dominik Cinčić, Tomislav Friščić   +12 more
wiley   +2 more sources

Using the Cocrystal Approach as a Promising Drug Delivery System to Enhance the Dissolution and Bioavailability of Formononetin Using an Imidazole Coformer

Pharmaceuticals
Background: Natural isoflavones are recognized for their diverse pharmacological activities; however, their low aqueous solubility presents a significant challenge for further development.
Jongyeob Kim, Sohyeon Lim, Minseon Kim, Eunmi Ban, Yongae Kim, Aeri Kim   +5 more
doaj   +1 more source

Crystal Structures, Thermal Analysis, and Dissolution Behavior of New Solid Forms of the Antiviral Drug Arbidol with Dicarboxylic Acids

Crystals, 2015
Salts of the antiviral drug arbidol (umifenovir) (Arb) with maleate (Mlc) and fumarate (Fum) anions have been obtained, and their crystal structures have been described.
Alex N. Manin, Artem O. Surov, Andrei V. Churakov, German L. Perlovich   +3 more
doaj   +1 more source

Advancing Therapies for Mycobacterial Diseases: From Small Molecules to Host‐Directed Strategies

Medicinal Research Reviews, EarlyView.
ABSTRACT The global burden of multidrug‐resistant tuberculosis (MDR‐TB) and the rising incidence of nontuberculous mycobacterial (NTM) infections highlight the urgent need for innovative therapeutic strategies. Current treatments are prolonged, toxic, and increasingly compromised by resistance and limited diagnostic capacity.
Tânia Silva, Alessandra Aiello, Tonino Alonzi, M. Alice Carvalho, Vladimir Finger, Delia Goletti, Sven Hoffner, Yousra Kherabi, Jan Korabecny, Julia Kulczyńska, Agnieszka Kyzioł, Alicia Lacoma, Filomena Martins, Zorica Nanovic, Sepideh Hosseiniporgham, Martina Hrast Rambaher, Leonardo Antonio Sechi, Daria Smalchuk, Grażyna Stochel, Lydia Tabernero, Nancy L. Tateosian, Violeta Valcheva, Anamarija Zega, Mafalda Sarraguça   +23 more
wiley   +1 more source

Biocatalytic synthesis of S‐adenosyl‐l‐methionine analogues for allosteric activation of cystathionine‐β‐synthase

The FEBS Journal, EarlyView.
Cystathionine‐β‐synthase (CBS) helps remove harmful homocysteine and supports the production of protective sulfur‐containing molecules. Using its natural activator, S‐adenosyl‐l‐methionine, as a template, we designed and tested 15 analogues. Three activated and stabilized the enzyme, including the newly identified S‐2‐amino‐adenosyl‐l‐methionine. These
Dalibor Nakládal, Žaneta Zajacová, Rick Oerlemans, Jana Havlikova, Gabriel Zorkócy, Lukáš Kerti, Katarína Sujová, Adrian Lengyel, Zoë van der Gun, Christina Yoseif, Adrianus Cornelis van der Graaf, Guido Krenning, Ján Kyselovič, Vladimír Frecer, Matthew R. Groves, Zdenko Levarski, André Heeres, Rob H. Henning, Leo E. Deelman   +18 more
wiley   +1 more source