Results 61 to 70 of about 8,547 (185)

Cannabinoids as Cocrystals [PDF]

Medical Cannabis and Cannabinoids, 2022
openaire   +3 more sources

A Chiral Saddle‐Shaped Nanographene With Two Heptagon‐Embedded [4]Helicenes

Angewandte Chemie International Edition, Volume 65, Issue 31, 27 July 2026.
We present a novel synthetic strategy toward a chiral saddle‐shaped nanographene (cSNG) via a two‐step oxidation of a prochiral anthracene precursor. The Scholl‐type oxidation first yields a key intermediate with sp3‐defect heptagons, and subsequent oxidative dehydrogenation affords fully conjugated cSNG.
Felix Trautner, Boris Borrisov, Philipp Royla, Hongqing Zhao, Hartmut Komber, Li Wan, Evgenia Dmitrieva, Ji Ma, Jan J. Weigand, Qun Yang, Xinliang Feng, Wenhui Niu   +11 more
wiley   +1 more source

Expansion of the Metal‐Involving Noncovalent Interaction Repertoire: The Case of Pd(II) and Pt(II) Triel Bonding

ChemPhysChem, Volume 27, Issue 13, 14 July 2026.
This study reveals that square planar Pd and Pt complexes can act as nucleophiles, forming directional triel bonds with boron‐based acceptors. Using energy decomposition analysis (EDA), quantum theory of atoms in molecules (QTAIM), and natural bond orbital (NBO), we demonstrate a transition from dispersion‐driven to dative‐covalent interactions.
Rosa M. Gomila, Antonio Frontera
wiley   +1 more source

Spectral characterization and vibrational mode study of cocrystal of acetaminophen and aspirin based on terahertz/Raman spectroscopy combined with DFT theory calculation

Results in Chemistry
In recent years, pharmaceutical cocrystal has become a hot field in drug development, which improves the solubility, stability, and bioavailability of drugs.
Haofei Sun, Bo Peng, Xinyi Bai, Bo Su, Cunlin Zhang, Hailin Cui, Shengbo Zhang, Kai Li   +7 more
doaj   +1 more source

Stafib‐2‐CR: an Improved Nanomolar and Selective Inhibitor of the Transcription Factor STAT5b Developed by Conformational Restriction of Stafib‐2

Chemistry – A European Journal, Volume 32, Issue 26, 11 July 2026.
Conformational restriction strategies to increase the activity and selectivity of the STAT5b inhibitor Stafib‐2 are presented. The best conformationally restricted inhibitor Stafib‐2‐CR has threefold higher activity against STAT5b than Stafib‐2. A cell‐permeable prodrug of Stafib‐2‐CR inhibits phosphorylation of STAT5b in cultured human leukemia cells ...
Theresa Münzel, Angela Berg, Christoph Protzel, Sylvie Schäfer, Alexander Jensen‐Feinhals, Thorsten Berg   +5 more
wiley   +1 more source

Daidzein-betaine cocrystal alleviates high-energy and low-protein diet induced fatty liver hemorrhagic syndrome in laying hens through gut-liver axis

Poultry Science
Fatty liver hemorrhagic syndrome (FLHS) severely endangers the health and productivity of laying hens, marked by hepatic steatosis and impaired lipid metabolism. Daidzein-betaine cocrystal improves lipid metabolism in the diet-induced obesity mice.
Yanling Sun, Tiantian Wang, Yu Zhang, Ning Ma, Xinghua Zhao, Xin He   +5 more
doaj   +1 more source

Research progress of high energy CL-20/HMX cocrystal explosive

Results in Chemistry
Cocrystal belongs to supramolecular chemistry and it is generally composed of different components including molecules, ions with certain molecular ratio and typical structure.
Guiyun Hang, Jintao Wang, Haijian Xue, Tao Wang, Wenli Yu, Huiming Shen   +5 more
doaj   +1 more source

Structural Characterization of Febuxostat/l-Pyroglutamic Acid Cocrystal Using Solid-State 13C-NMR and Investigational Study of Its Water Solubility

Crystals, 2017
Febuxostat (FB) is a poorly water-soluble drug that belongs to BCS class II. The drug is employed for the treatment of inflammatory disease arthritis urica (gout), and the free base, FB form-A, is most preferred for drug formulation.
Ji-Hun An, Changjin Lim, Hyung Chul Ryu, Jae Sun Kim, Hyuk Min Kim, Alice Nguvoko Kiyonga, Minho Park, Young-Ger Suh, Gyu Hwan Park, Kiwon Jung   +9 more
doaj   +1 more source

Triethylamine vapor-induced cyclization reaction in cocrystals leading to cocrystal-to-polycrystal transformation

Nature Communications
The structural transformation of crystals triggered by external stimuli is a fascinating area in materials science and supramolecular chemistry. Despite the potential of organic reactions driving crystal conversions, its exploration remains limited ...
Ling Zhu, Xiaoli Zhao, Yanfei Niu, Lianrui Hu, Weitao Dou, Hai-Bo Yang, Lin Xu, Ben Zhong Tang   +7 more
doaj   +1 more source

Mechanochemical Synthesis of a Cocrystal of Two Supramolecular Hydrogen-Bonded Aggregates of 1,3,6,8-Tetraazatricyclo[4.3.1.13,8]undecane (TATU) with 4-tert-Butylphenol Bearing Different Hydrogen Bonding Interactions

Crystals, 2018
The synthesis and single crystal structure of a new cocrystal, which is composed of OHphenolic∙∙∙OHphenolic∙∙∙Naminalic supramolecular heterosynthons assembled from 4-tert-butylphenol and the macrocyclic aminal TATU, is presented.
Augusto Rivera, Jicli José Rojas, Jaime Ríos-Motta, Michael Bolte   +3 more
doaj   +1 more source