Results 71 to 80 of about 8,500 (189)
Understanding the formation of apremilast cocrystals [PDF]
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2019 Apremilast (APR), an anti-psoriatic agent, easily forms isostructural cocrystals and solvates with aromatic entities, often disobeying at the same time Kitaigorodsky's rule as to the saturation of possible hydrogen-bonding sites. In this paper the reasons for this peculiar behavior are investigated, employing a joint experimental and theoretical ...
Marta K. Dudek +7 more
openaire +3 more sources
Energy Transfer in Nanodroplet‐Based Luminescent Solar Concentrators
Small, EarlyView.We present novel luminescent solar concentrators (LSCs) featuring polymer composites with fluorescent dye‐doped oil nanodroplets. This liquid environment ensures high dye solubility and preserves fluorescence quantum yields, even at high local dye concentrations.
Lorenzo Vallan +7 more
wiley +1 more source
Pharmaceutical Cocrystals and Their Physicochemical Properties [PDF]
Crystal Growth & Design, 2009 This review article will highlight and discuss the advances made over the last 10 years pertaining to physical and chemical property improvements through pharmaceutical cocrystals and, hopefully, draw closer the fields of crystal engineering and pharmaceutical sciences.
Schultheiss, Nate, Newman, Ann
openaire +2 more sources
Chiral (Stereoselective) Drugs, Asymmetric Synthesis, and Racemic Resolution Methods
Chirality, Volume 38, Issue 7, July 2026.Chirality is crucial in drug development since both biological targets in the organism and the majority of pharmaceutical compounds are chiral. The synthesis and resolution of chiral compounds are critical steps while developing chiral drugs. Asymmetric synthesis and racemic resolution are the two most common methods for obtaining enantiopure drugs ...
Burcu Karayavuz +1 more
wiley +1 more source
European Journal of Inorganic Chemistry, Volume 29, Issue 17, 17 June 2026.Intramolecular (RO)2PO→Halogen interaction versus intermolecular (RO)2PO···HOH hydrogen bonds. Although the O···I distance is shorter than the sum of the van der Waals radii of the atoms involved, there is no covalency involved in this interaction.
David Mross +6 more
wiley +1 more source
ChemMedChem, Volume 21, Issue 11, 15 June 2026.We developed new derivatives of the cancer drug ponatinib, significantly reducing and altering its spectrum of target kinases. Compound 5 retained the efficacy in inhibiting the colony formation of MDA‐MB‐231 cells and acted primarily on B‐Raf and Flt‐1 as its main targets in a kinase panel.
Tobias Betzholz +7 more
wiley +1 more source
Aggregate, Volume 7, Issue 6, June 2026.A pair of π‐extended chiral triangular prisms based on pyromellitic diimide is synthesized from enantiopure macrocyclic precursors. They exhibit orange fluorescence and solvent‐dependent self‐assembly, enabling chiroptical inversion and amplification with |glum| values up to 1.15 × 10−2. Single‐crystal structures reveal solvent‐controlled conformations
Si‐Dan Guo +8 more
wiley +1 more source
Aggregate, Volume 7, Issue 6, June 2026.The Graphical Abstract summarizes the key concepts of this review, covering supramolecular assembly strategies, CPP material integration, multicolor emission, information encryption, and flexible optoelectronic applications. ABSTRACT Circularly polarized luminescence (CPL) and room‐temperature phosphorescence (RTP) materials are crucial for advanced ...
Wei Zhang +6 more
wiley +1 more source
Recent advances in organic broad‐spectrum photodetection materials and devices
InfoMat, Volume 8, Issue 6, June 2026.This review systematically outlines the evolution of organic photodetectors from fullerene‐based to advanced non‐fullerene acceptors, highlighting how molecular engineering (e.g., D–A, quinoidal, and A‐D‐A′‐D‐A architectures) extends spectral response into the short‐wave infrared region.
Yilin Zhao +3 more
wiley +1 more source