Results 71 to 80 of about 14,800 (170)
Solvatomechanical Bending of Organic Charge Transfer Cocrystal
, 2018 We report here a new ternary solvated (perylene-TCNB)·2THF cocrystal, which can transform into binary perylene-TCNB cocrystal reversibly by successive desorption or absorption of THF solvent.
Yanqiu Sun (1276917) +4 more
core +3 more sources
Chemistry &Biodiversity, Volume 23, Issue 11, November 2026.Integrated LC‐HRMS metabolite profiling, cytotoxicity evaluation, and molecular docking revealed the anticancer potential of Ipomoea hederifolia L. root extract through modulation of EGFR‐, ERBB2‐, and MET‐mediated pathways in HepG2 liver cancer cells.
Poonam Joshi, Anjali Tripathi, Sandhya S
wiley +1 more source
A KATing Edge Perspective on KAT6A Inhibitors as Anticancer Agents
ChemMedChem, Volume 21, Issue 20, 28 October 2026.This perspective efficiently summarizes the development of lysine acetyltransferase (KAT) inhibitors as anticancer agents, and the most clinically advanced KAT6A inhibitor, prifetrastat, entered Phase III clinical trials in 2025. KAT6A structural biology and structure activity relationships for acylsulfonylhydrazides, [1,2,4]thiadiazines, and ...
Rochelle Woodland +7 more
wiley +1 more source
International Journal of Pharmaceutics: XEmodin (EMO) shows therapeutic promise for ulcerative colitis (UC), yet its clinical utility is hampered by low bioavailability. To rationally overcome this limitation, this study employed cocrystal engineering, strategically selecting ...
Meiru Liu +12 more
doaj +1 more source
Synthesis, Updated Characterization, and Reactivity of Low‐Valent Titanocene Complexes
European Journal of Inorganic Chemistry, Volume 29, Issue 30, 27 October 2026.Syntheses and characterizations are provided for a series of low‐valent titanocene complexes including halotitanocene(III) dimers, [Cp2Ti(κ2‐DME)][BAr4] cations, and heterobimetallic [Cp2Ti(μ‐Cl)2AlR2]. Additionally, a monomeric titanacyclopropene complex featuring a pendent phosphine was prepared, and C─F bond activation upon reduction of [Cp{η5:κ2F2 ...
Griffin J. LaChapelle +2 more
wiley +1 more source
Molecules, 2019 Vibrational modes of pyrazinamide (PZA), 3-hydroxybenzoic acid (3-hBA), and their cocrystal were characterized using terahertz time-domain (THz-TDS) and Raman vibrational spectroscopic techniques.
Qiqi Wang, Jiadan Xue, Zhi Hong, Yong Du
doaj +1 more source
Cocrystal Eutectic Constants and Prediction of Solubility Behavior
, 2016 Cocrystal eutectic constants (Keu), the ratio of solution concentrations of cocrystal components at the eutectic point, are a fundamental indicator of phase behavior and are shown to be a function of the solubility ratio of cocrystal and drug in pure ...
David J. Good (1469488) +1 more
core +1 more source
Deriving General Energy Predictors for Pnictogen Bonding
Chemistry – A European Journal, Volume 32, Issue 39, 22 October 2026.This study derives general energetic predictors for pure pnictogen bonds from nitrogen to bismuth based on the potential energy density at the bond critical point. The research highlights the increasing occurrence of secondary interactions for heavier elements.
Jan Langwald, Antonio Frontera
wiley +1 more source
Hitting Coronaviruses Where It Hurts: Antiviral Strategies Targeting Viral Proteins
ChemMedChem, Volume 21, Issue 19, 14 October 2026.Viral proteins represent key vulnerabilities in human coronaviruses (HCoVs). This review outlines inhibitors targeting spike (S), main protease (Mpro), papain‐like protease (PLpro), and RNA‐dependent RNA polymerase (RdRp), mapping chemically diverse strategies that disrupt entry and replication, and provides an integrated view of current candidates ...
Álvaro de la Cruz‐Potenciano +3 more
wiley +1 more source
, 2014 Cocrystal nanofibres of cobalt octaethylporphyrin and tetracyanoquinodimethane were prepared by a facile solution method and fully characterized by SEM, AFM, XRD, Raman, EDX, and UV-vis-NIR.
Xiao Y(肖燕) +4 more
core