Results 71 to 80 of about 8,547 (185)

Investigation of the Storage and Stability as Well as the Dissolution Rate of Novel Ilaprazole/Xylitol Cocrystal

Pharmaceutics
Reflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam, Changjin Lim, Yongdae Kim, Bokyoung Yoon, Taewoo Park, Woo-Sik Kim, Ji-Hun An   +6 more
doaj   +1 more source

Crystal structure, Hirshfeld surface and intermolecular interaction energy analysis of the halogen-bonded 1:1 cocrystal 1-bromo-3,5-dinitrobenzene–N,N-dimethylpyridin-4-amine

Acta Crystallographica Section E: Crystallographic Communications
The structure of the 1:1 cocrystal formed between 1-bromo-3,5-dinitrobenzene and N,N-dimethylpyridin-4-amine that features a C—Br...N halogen bond is reported. The cocrystal, C6H3BrN2O4·C7H10N2, crystalizes in the monoclinic space group P21/c with Z = 4.
Eric Bosch
doaj   +1 more source

Silybin Cocrystals with Improved Solubility and Bioavailability

Pharmaceuticals
Backgroud/Objectives: Silymarin, an extract from milk thistle, is widely recognized for its therapeutic potential in treating liver disorders. However, its clinical utility is limited by the poor solubility and low bioavailability of its key active ...
Bingqing Zhu, Zhenfeng Ding, Xiaoyi Rong, Shengqiang Li, Xuefeng Mei   +4 more
doaj   +1 more source

Cocrystal Prediction Based on Deep Forest Model—A Case Study of Febuxostat

Crystals
To aid cocrystal screening, a deep forest-based cocrystal prediction model was developed in this study using data from the Cambridge Structural Database (CSD). The positive samples in the experiment came from the CSD.
Jiahui Chen, Zhihui Li, Yanlei Kang, Zhong Li   +3 more
doaj   +1 more source

Urea Cocrystals as a Potential Fertilizer for Turfgrass: Responses of ‘Tifway’ Hybrid Bermudagrass and Nitrogen Release Behavior

HortTechnology
Urea cocrystal materials are a potential fertilizer source that has shown to decrease environmental nitrogen losses. Novel nitrogen (N)-containing urea cocrystal fertilizers, CaSO4·4urea (UC1) and Ca(H2PO4)2·4urea (UC2), were synthesized using the ...
Reagan W. Hejl, Julia Farias, Jonas Baltrusaitis, Clinton F. Williams, Mohamed Eisa, Dovilė Ragauskaitė, Desalegn D. Serba   +6 more
doaj   +1 more source

PHARMACEUTICAL COCRYSTALS

UPI Journal of Chemical and Life Sciences
Low aqueous solubility and concomitant oral bioavailability are the major glitches found in converting the active pharmaceutical ingredients to new pharmaceutical products. Many methods are in existence to improve the solubility of poorly water-soluble drugs.
Vinod Kumar K, Vyshnavi K, Reethi N, Reethi N, Siddardh H, Vaikunteswar A   +5 more
openaire   +1 more source

Energetic cocrystals – structural studies of nitrotriazolone salts and cocrystals [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2013
Hayleigh J. Lloyd, S. Corless, C. R. Pulham   +2 more
openaire   +1 more source

Crystal Structure Prediction and Intermolecular Interaction Study of CL-20/NQ Cocrystal Explosive

四川大学学报. 自然科学版, 2016
Density functional theory was employed to investigate the four structures (a, b, c, d) of CL-20/NQ cocrystal. The intermolecular interaction, explosive property, and crystal structure were analyzed and predicted in this paper.
GOU Rui-Jun, ZHAO Yuan-Yuan, ZHANG Shu-Hai, DING Xiong, YANG Wen-Sheng, GAO Hong-Fei   +5 more
doaj  

An Antibacterial "Drug-Drug" Cocrystal of Trimethoprim with Sulfathiazole Achieving Synchronized Dual-Drug Release and Pharmacokinetics. [PDF]

ACS Omega
Li WH, Sun XH, Chen X, Gao SH, Li FY, Mo H, Hu XY, Wang XK, Liu F.   +8 more
europepmc   +1 more source

The cocrystals of isorhamnetin and isoliquiritigenin with 4,4'-bipyridine: system characterization, stability, dissolution and anticancer activity. [PDF]

RSC Adv
Liu Y, Lei J, Li T, Zhong A, Zhu Z, Lu J, Wang Z, Zhao P, Wu Z.   +8 more
europepmc   +1 more source