Results 91 to 100 of about 14,800 (170)

Large volumetric thermal expansion of a novel organic cocrystal over a wide temperature range

open access: yes, 2018
A novel cocrystal ABN·2DMABN shows the largest volumetric thermal expansion over a wide temperature range of 100–300 K for an organic cocrystal.
Lukman O. Alimi   +3 more
core   +1 more source

Triethylamine vapor-induced cyclization reaction in cocrystals leading to cocrystal-to-polycrystal transformation

open access: yesNature Communications
The structural transformation of crystals triggered by external stimuli is a fascinating area in materials science and supramolecular chemistry. Despite the potential of organic reactions driving crystal conversions, its exploration remains limited ...
Ling Zhu   +7 more
doaj   +1 more source

Mechanochemical Synthesis of a Cocrystal of Two Supramolecular Hydrogen-Bonded Aggregates of 1,3,6,8-Tetraazatricyclo[4.3.1.13,8]undecane (TATU) with 4-tert-Butylphenol Bearing Different Hydrogen Bonding Interactions

open access: yesCrystals, 2018
The synthesis and single crystal structure of a new cocrystal, which is composed of OHphenolic∙∙∙OHphenolic∙∙∙Naminalic supramolecular heterosynthons assembled from 4-tert-butylphenol and the macrocyclic aminal TATU, is presented.
Augusto Rivera   +3 more
doaj   +1 more source

Structure determination of the theophylline-nicotinamide cocrystal: a combined powder XRD, 1D solid-state NMR, and theoretical calculation study

open access: yes, 2014
The crystal structure of a powder pharmaceutical cocrystal, theophylline-nicotinamide (1 : 1) crystal complex, is determined for the first time by using a combination of X-ray powder diffraction (XRPD), 1D solid state NMR, as well as density functional ...
Wenslow, RM (Wenslow, Robert M., Jr.)   +6 more
core  

High-shear granulation as a manufacturing method for cocrystal granules

open access: yes, 2013
Cocrystal formation allows the tailoring of physicochemical as well as of mechanical properties of an API. However, there is a lack of large-scale manufacturing methods of cocrystals.
Leopold, Claudia S   +4 more
core   +1 more source

Investigation of the Storage and Stability as Well as the Dissolution Rate of Novel Ilaprazole/Xylitol Cocrystal

open access: yesPharmaceutics
Reflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam   +6 more
doaj   +1 more source

Syntheses and pharmacokinetics properties of an iloperidone pharmaceutical cocrystal [PDF]

open access: yes, 2014
We report here a pharmaceutical cocrystal, which was composed of iloperidone with 3, 5-pyridinedicarboxlic acid by crystal engineering strategy. It was characterized by single crystal X-ray and powder X-ray diffraction, which demonstrated that the ...
Cui, Xiao-Qiang   +5 more
core   +1 more source

Thermodynamic and Crystallization of Lamotrigine Cocrystal

open access: yes, 2019
Two novel lamotrigine cocrystals, namely, lamotrigine (LAM) phthalimide (PTL) cocrystal (1) and lamotrigine (LAM) succinimide (SUC) cocrystal monohydrate (1:1:1) (2), were successfully synthesized by liquid-assisted grinding and evaporative ...
An ping Liao (7423916)   +13 more
core   +1 more source

Kinetic entrapment of a hidden curcumin cocrystal with phloroglucinol

open access: yes, 2014
© 2014 American Chemical Society. The existence of a cocrystal between curcumin (CUR) and phloroglucinol (PHL) was suspected but could not be demonstrated in a recent systematic effort to synthesize novel curcumin cocrystals.
Wai Wing Ng   +13 more
core   +1 more source

Crystal structure, Hirshfeld surface and intermolecular interaction energy analysis of the halogen-bonded 1:1 cocrystal 1-bromo-3,5-dinitrobenzene–N,N-dimethylpyridin-4-amine

open access: yesActa Crystallographica Section E: Crystallographic Communications
The structure of the 1:1 cocrystal formed between 1-bromo-3,5-dinitrobenzene and N,N-dimethylpyridin-4-amine that features a C—Br...N halogen bond is reported. The cocrystal, C6H3BrN2O4·C7H10N2, crystalizes in the monoclinic space group P21/c with Z = 4.
Eric Bosch
doaj   +1 more source

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