Results 91 to 100 of about 14,340 (184)

Thermodynamics and crystallization of a theophylline-salicylic acid cocrystal

open access: yes, 2015
A 1: 1 theophylline-salicylic acid cocrystal has been successfully prepared by slurry conversion crystallization in a 1 : 1 molar ratio slurry of theophylline and salicylic acid in chloroform.
Chen, Hong   +2 more
core   +1 more source

Advances in Organic Aggregates for Biomedical Phototheranostics

open access: yesMedComm – Biomaterials and Applications, Volume 5, Issue 3, September 2026.
Organic aggregates offer aggregation‐regulated photophysical properties for biomedical phototheranostics, enabling enhanced fluorescence, stabilized room‐temperature phosphorescence, and efficient photoacoustic/photothermal responses. This review highlights molecular design strategies, excited‐state energy modulation, biomedical applications, and ...
Bowen Fu, Yayun Peng, Ting Cai
wiley   +1 more source

Engineering cocrystal and polymorph architecture via pseudoseeding

open access: yes, 2009
We use a cocrystal with components arranged in a 1D hydrogen-bonded chain as a pseudoseed to template the components of a cocrystal that otherwise forms a photoactive 0D assembly to form a photostable 1D chain structure.
Friščić, Tomislav; id_orcid   +1 more
core   +1 more source

Novel {Pb6} wheels based zeolite‐type metal‐organic framework for wide temperature range and high sensitivity of luminescent thermometer

open access: yesSmart Molecules, Volume 4, Issue 3, September 2026.
The expansion of {Pb6} wheels in zeolite‐type MOFs led to emission thermal quenching of 93%, relative sensitivity of 1.03% K−1 (intensity‐based) and 0.97% K−1 (lifetime‐based) in a wide temperature range of 298–423 K. Abstract The development of luminescent thermometers synchronously exhibiting high sensitivity and stability in a wide temperature range
Yi‐Na Li   +6 more
wiley   +1 more source

Thermodynamics and Crystallization of the Theophylline-Glutaric Acid Cocrystal

open access: yes, 2013
This work investigates the thermodynamics and crystallization of the theophylline glutaric acid 1:1 cocrystal. It is found that the cocrystal physically decomposes at 120 degrees C (i.e., in the range between the melting points of the two pure compounds).
Rasmuson, Åke C.,, Zhang, Shuo,
core   +1 more source

In Vitro Dissolution Profile of Nitazoxanide Oral Suspension: Applying an HPLC Method in Drug Solubility and Chemical Stability Studies, With a Direct Impact on In Vitro Release

open access: yesSEPARATION SCIENCE PLUS, Volume 9, Issue 9, September 2026.
Proposal of a new in vitro dissolution method for nitazoxanide oral suspension, addressing critical aspects of the drug solubility and chemical stability. ABSTRACT Nitazoxanide is a broad‐spectrum prodrug widely used against protozoa, helminthes, and anaerobic bacteria.
Gabriele Cavalcante Rosa   +4 more
wiley   +1 more source

Single‐crystal structure determination of psilocybin after dehydration

open access: yesActa Crystallographica Section C, Volume 82, Issue 9, Page 542-546, September 2026.
The structures of the hydrous and first anhydrous phases of crystalline psilocybin have been determined using single‐crystal X‐ray diffraction.The crystal structure of the known low‐temperature anhydrous phase of psilocybin {3‐[2‐(dimethylamino)ethyl]‐1H‐indol‐4‐yl dihydrogen phosphate, C12H17N2O4P} is reported.
Sonya K. Emmett   +7 more
wiley   +1 more source

High-shear granulation as a manufacturing method for cocrystal granules

open access: yes, 2013
Cocrystal formation allows the tailoring of physicochemical as well as of mechanical properties of an API. However, there is a lack of large-scale manufacturing methods of cocrystals.
Leopold, Claudia S   +4 more
core   +1 more source

Investigation of the Storage and Stability as Well as the Dissolution Rate of Novel Ilaprazole/Xylitol Cocrystal

open access: yesPharmaceutics
Reflux esophagitis, a treatment for gastric ulcers known as Ilaprazole (Ila), is not stable during storage and handling at room temperature, requiring storage at 5 degrees Celsius. In this study, to address these issues with Ila, coformers rich in oxygen
Sihyun Nam   +6 more
doaj   +1 more source

KAT6A–inhibitor co‐crystal structures: tackling a challenging crystallization target via two alternative approaches

open access: yesActa Crystallographica Section D, Volume 82, Issue 9, Page 1111-1124, September 2026.
We report a novel cysteine‐to‐serine surface‐mutation approach to determine co‐crystal structures of KAT6A with small‐molecule inhibitors and compare it with the previously published MYSTcryst approach which uses mutated KAT8 as a surrogate for KAT6A.
Vera Puetter   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy