Results 61 to 70 of about 16,526 (214)

Preparation of Theophylline-Benzoic Acid Cocrystal and On-Line Monitoring of Cocrystallization Process in Solution by Raman Spectroscopy

Crystals, 2019
Pure theophylline-benzoic acid cocrystal was prepared via slurry and cooling crystallization in solution to overcome the disadvantages of existing preparation methods.
Yaohui Huang, Ling Zhou, Wenchao Yang, Yang Li, Yongfan Yang, Zaixiang Zhang, Chang Wang, Xia Zhang, Qiuxiang Yin   +8 more
doaj   +1 more source

Decreasing the hygroscopicity of ammonium dinitramide (ADN) through cocrystallization

Energetic Materials Frontiers, 2022
To decrease the hygroscopicity of ADN—a energetic oxidizer, this study developed a new cocrystal composed of ADN and 18C6 (18-crown-6) at a 1:1 ​M ratio through cocrystallization using the solvent evaporation method.
Shen Qiao, Hong-zhen Li, Zong-wei Yang
doaj   +1 more source

Cocrystal Transition Points: Role of Cocrystal Solubility, Drug Solubility, and Solubilizing Agents [PDF]

Molecular Pharmaceutics, 2015
In this manuscript we bring together concepts that are relevant to the solubilization and thermodynamic stability of cocrystals in the presence of drug solubilizing agents. Simple equations are derived that allow calculation of cocrystal solubilization and transition point solubility.
Maya P, Lipert, Naír, Rodríguez-Hornedo   +1 more
openaire   +2 more sources

RS, S (+) - and R (−)-ibuprofen cocrystal polymorphs: Vibrational spectra, XRD measurement and DFT calculation studies

Heliyon
In this paper, cocrystal polymorphs of RS-ibuprofen (RS-IBU), S (+)-ibuprofen (S(+)-IBU), R (−)-ibuprofen (R(−)-IBU) with nicotinamide (NIC) were synthesized by different methods. RS-IBU is a chiral drug with only one chiral center in the molecule, which
Yaqi Jing, Qiuhui Zhao, Jiale Zhang, Jiadan Xue, Jianjun Liu, Jianyuan Qin, Zhi Hong, Yong Du   +7 more
doaj   +1 more source

Charge Transport in Ternary Charge‐Transfer Solid Solution Single Crystals

Advanced Functional Materials, EarlyView.
This study deconvolutes the roles of indirect (superexchange) and direct electronic coupling on charge transport in single crystals of an organic charge‐transfer molecular semiconductor (OSC). This model system elegantly demonstrates that structural defects introduced by chemical dopants play a significant role in the electronic performance ...
Jonathan C. Novak, Manikanta Makala, Edith L. MacKenzie, Veaceslav Coropceanu, Kimberly Agosto, Abigail A. Moravek, Oana D. Jurchescu, Ren A. Wiscons   +7 more
wiley   +1 more source

Optimized solubility and bioavailability of genistein based on cocrystal engineering

Natural Products and Bioprospecting, 2023
With various potential health-promoting bioactivities, genistein has great prospects in treatment of a series of complex diseases and metabolic syndromes such as cancer, diabetes, cardiovascular diseases, menopausal symptoms and so on.
Zhipeng Wang, Qi Li, Qi An, Lixiang Gong, Shiying Yang, Baoxi Zhang, Bin Su, Dezhi Yang, Li Zhang, Yang Lu, Guanhua Du   +10 more
doaj   +1 more source

Complete Cocrystal Formation during Resonant Acoustic Wet Granulation: Effect of Granulation Liquids

Pharmaceutics, 2021
The manufacturing of solid pharmaceutical dosage forms composed of cocrystals requires numerous processes during which there is risk of dissociation into parent molecules.
Ryoma Tanaka, Supisara Osotprasit, Jomjai Peerapattana, Kazuhide Ashizawa, Yusuke Hattori, Makoto Otsuka   +5 more
doaj   +1 more source

Thermally Activated Delayed Fluorescence in Phase‐Separated Nanostructures

Advanced Functional Materials, EarlyView.
A supramolecular, phase‐separation driven strategy yields charge transfer (CT) complexes from alternating electron‐deficient pyromellitic diimide and electron‐rich 4,5‐dibromoveratrole. The resulting CT complexes self‐assemble into lamellar nanosheets with nanometer‐sized domains that exhibit thermally activated delayed fluorescence (TADF) at room ...
Bart W.L. van den Bersselaar, Giovanni M. Beneventi, Philip M. Greißel, Lukas A. Mai, Stefan J. D. Maessen, Bas F.M. de Waal, E.W. Meijer, Dirk M. Guldi, Ghislaine Vantomme   +8 more
wiley   +1 more source

Beyond the Edge: Charge‐Transfer Excitons in Organic Donor‐Acceptor Cocrystals

Advanced Functional Materials, EarlyView.
Complex excitonic landscapes in acene–perfluoroacene cocrystals are unveiled by polarization‐resolved optical spectroscopy and many‐body theory. This systematic study of a prototypical model system for weakly interacting donor–acceptor compounds challenges common views of charge‐transfer excitons, providing a refined conceptual framework for ...
Sebastian Anhäuser, Ana M. Valencia, Sergei I. Ivlev, Marc Zeplichal, Andreas Terfort, Caterina Cocchi, Gregor Witte   +6 more
wiley   +1 more source

Near‐Infrared Cocrystal Nanofluorophore with Enhanced Two‐Photon Absorption Cross Sections

Advanced Science, EarlyView.
In this study, organic cocrystal nanoparticles (BP4TC‐NPs) were prepared via a nanoprecipitation method using an amphiphilic surfactant. The resulting cocrystal nanoparticles exhibit exceptional nonlinear optical properties and bioimaging capabilities.
Liangmeng Hao, Ying Ni, Jiawei Huang, Yucheng Wang, Fan Liu, Xu Wang, Lei Kang, Zheshuai Lin, Weigang Zhu   +8 more
wiley   +1 more source