Solvates, salts, and cocrystals : a proposal for a feasible classification system [PDF]
The design of pharmaceutical cocrystals has initiated widespread debate on the classification of cocrystals. Current attempts to classify multicomponent crystals suffer from ambiguity, which has led to inconsistent definitions for cocrystals and for ...
De Gelder, R. +4 more
core +2 more sources
Fluorescent proteins: A journey from the cell to extreme environments in material science
Applications of proteins and microorganisms as tools or effectors in material science. Abstract This review presents the progression from the use of fluorescent proteins (FPs) and chromoproteins as bioimaging labels and sensors to the strategic engineering of their properties for robust functionality in synthetic and non‐biological environments ...
Bianca Menchicchi +3 more
wiley +1 more source
Thermodynamic investigation of carbamazepine-saccharin co-crystal polymorphs [PDF]
YesPolymorphism in active pharmaceutical ingredients (APIs) can be regarded as critical for the potential that crystal form can have on the quality, efficacy and safety of the final drug product.
Aitipamula +51 more
core +1 more source
Abstract Trypanosomatids are protozoan parasites that remain a global health challenge due to the limited efficacy, safety, and durability of current treatments. Acetate: succinate CoA transferase (ASCT), together with succinyl‐CoA synthase (SCS), forms the ASCT/SCS cycle that fuels ATP production and generates acetate, a central metabolic intermediate
Kota Mochizuki +13 more
wiley +1 more source
Application of Twin Screw Extrusion in the Manufacture of Cocrystals, Part I: Four Case Studies
The application of twin screw extrusion (TSE) as a scalable and green process for the manufacture of cocrystals was investigated. Four model cocrystal forming systems, Caffeine-Oxalic acid, Nicotinamide-trans cinnamic acid, Carbamazepine-Saccharin, and ...
Karthik Nagapudi +4 more
doaj +1 more source
Vibrational assignments of two polymorphic forms of metaxolone by using DFT calculations and the SQM methodology [PDF]
A theoretical study has been performed on the musclerelaxant 5-[(3, 5-dimethylphenoxy)methyl]-1,3-oxazolidin-2-one, of generic name metaxolone (MTX), by using the hybridB3LYP/6-31G calculations in the gas phase and theexperimental available infrared and ...
Brandan, Silvia Antonia +3 more
core
Cocrystal habit engineering to improve drug dissolution and alter derived powder properties [PDF]
YesObjectives: Cocrystallization of sulfadimidine (SDM) with suitable coformers, such as 4-aminosalicylic acid (4-ASA), combined with changes in the crystal habit can favourably alter its physicochemical properties.
Healy, A.M. +4 more
core +1 more source
Stability and solid-state polymerization reactivity of imidazolyl- and benzimidazolyl-substituted diacetylenes: pivotal role of lattice water [PDF]
International audience1,6-Bis(1-imidazolyl)-2,4-hexadiyne (1) and1,6-bis(1-benzimidazolyl)-2,4-hexadiyne (5) have beenpreparedby a novel method that consists in refluxing excess imidazole and benzimidazole with 2,4-hexadiyne-1,6-diol bis(p ...
Boury, Bruno +7 more
core +4 more sources
Novel Charge-Transfer Materials via Cocrystallization of Planar Aromatic Donors and Spherical Polyoxometalate Acceptors [PDF]
Spherical polyoxometalates (POMs) such as M6O192- and SiM12O404- (with M = Mo or W) and planar arene donors (anthracenes and pyrenes) can be cocrystallized (despite their structural incompatibility) by attaching a cationic “anchor” onto the arene which ...
Hubig, S. M. +4 more
core +1 more source
Searching for Suitable Kojic Acid Coformers: From Cocrystals and Salt to Eutectics
Renren Sun +4 more
openalex +1 more source

