Stability and solid-state polymerization reactivity of imidazolyl- and benzimidazolyl-substituted diacetylenes: pivotal role of lattice water [PDF]
, 2013 International audience1,6-Bis(1-imidazolyl)-2,4-hexadiyne (1) and1,6-bis(1-benzimidazolyl)-2,4-hexadiyne (5) have beenpreparedby a novel method that consists in refluxing excess imidazole and benzimidazole with 2,4-hexadiyne-1,6-diol bis(p ...
Boury, Bruno +7 more
core +4 more sources
Vibrational assignments of two polymorphic forms of metaxolone by using DFT calculations and the SQM methodology [PDF]
, 2018 A theoretical study has been performed on the musclerelaxant 5-[(3, 5-dimethylphenoxy)methyl]-1,3-oxazolidin-2-one, of generic name metaxolone (MTX), by using the hybridB3LYP/6-31G calculations in the gas phase and theexperimental available infrared and ...
Brandan, Silvia Antonia +3 more
core
Daidzein cocrystals: An opportunity to improve its biopharmaceutical parameters
Heliyon, 2019 The present study involves the contribution of cocrystallization towards the modification of the biopharmaceutical parameters of poorly watersoluble plant-originated isoflavone, daidzein (DAID). The cocrystals were prepared with GRAS status coformers i.e.
Yashika Bhalla +3 more
doaj +1 more source
Ionic Cocrystals of Etiracetam and Levetiracetam: The Importance of Chirality for Ionic Cocrystals
Crystal Growth & Design, 2019 A striking variety of anhydrous and hydrated ionic cocrystals (ICCs) of the enantiopure antiepileptic drug (AED) levetiracetam and of its racemic intermediate etiracetam with the pharmaceutically acceptable salts CaCl2 and MgCl2 was synthesized and structurally characterized.
Lixing Song +5 more
openaire +3 more sources
Apremilast Cocrystals with Phenolic Coformers
MoleculesApremilast (APR) is an anti-inflammatory drug commonly used in the treatment of psoriasis. In efforts to enhance its solubility, several cocrystals with similar structural features have been developed. This study investigates the cocrystallization of APR with four phenolic-type coformers: phenol, catechol, pyrogallol, and hydroxyquinol. These coformers
Yelizaveta Naumkina +3 more
openaire +3 more sources
Energetic cocrystals – structural studies of nitrotriazolone salts and cocrystals [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2013 Hayleigh J. Lloyd +2 more
openaire +1 more source
Insights into antibody catalysis: Structure of an oxygenation catalyst at 1.9-Å resolution [PDF]
, 1996 The x-ray crystal structures of the sulfide oxidase antibody 28B4 and of antibody 28B4 complexed with hapten have been solved at 2.2-Å and 1.9-Å resolution, respectively.
Hsieh-Wilson, Linda C. +2 more
core
Modularity in Organic Solid State and Supramolecular Chemistry [PDF]
, 2006 Connection between the concept of modularity and how it relates to both organic solid state and supramolecular chemistry is discussed. It is demonstrated how the interrelationship between the three areas can be exploited to control chemical reactivity in
Leonard R. MacGillivray +1 more
core +1 more source
Types of scaffolds and their application in bone tissue engineering [PDF]
, 2015 Bone tissue engineering is founded on the conception of bone structure, bone mechanics and tissue creature as it aims to restore, maintain, or improve tissue functions that are defective or have been lost by different pathological conditions.
Bosnakovski, Darko, Volceva, Milena
core
Functional molecular cocrystals [PDF]
Acta Crystallographica Section A Foundations of Crystallography, 2007 L. R. MacGillivray +3 more
openaire +1 more source