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Establishment of cocrystal cocktail grinding method for rational screening of pharmaceutical cocrystals

International Journal of Pharmaceutics, 2012
Cocrystals (CCs) used in the pharmaceutical industry are defined as complex crystals formed by reaction between an API and a cocrystal former (CCF); unlike salts, CCs do not show proton transfer. Recently, pharmaceutical CCs have been used to improve the drug-likeness of APIs, such as solubility and stability.
Katsuhiko, Yamamoto   +2 more
openaire   +2 more sources

Three cocrystals and a cocrystal salt of pyrimidin-2-amine and glutaric acid

Acta Crystallographica Section C Structural Chemistry, 2015
Four new cocrystals of pyrimidin-2-amine and propane-1,3-dicarboxylic (glutaric) acid were crystallized from three different solvents (acetonitrile, methanol and a 50:50 wt% mixture of methanol and chloroform) and their crystal structures determined. Two of the cocrystals, namely pyrimidin-2-amine–glutaric acid (1/1), C4H5N3·C6H8O4, (I) and (II), are ...
Isaac, Odiase   +5 more
openaire   +2 more sources

COCRYSTAL SOLUBILITY

2017
The aim of this project is to improve solubility and dissolution rate of active pharmaceutical ingrednient via cocrystallization.
openaire   +1 more source

Synthetic Approaches to Halogen Bonded Ternary Cocrystals

Angewandte Chemie - International Edition, 2021
Sourav Roy   +2 more
exaly  

PHARMACEUTICAL COCRYSTALS

2017
The aim of this project is to improve cocrystal screening and solubility prediction methods.
openaire   +1 more source

Mechanosynthesis of Higher‐Order Cocrystals: Tuning Order, Functionality and Size in Cocrystal Design**

Angewandte Chemie - International Edition, 2021
Yongxin Li   +2 more
exaly  

Unlocking the potential of drug-drug cocrystals – A comprehensive review

Journal of Controlled Release, 2022
Vandana Patravale
exaly  

Energetic Cocrystals

2023
Chaoyang Zhang, Jing Huang, Rupeng Bu
openaire   +1 more source

COCRYSTAL

2022
BAXTER ANDREW   +3 more
openaire   +1 more source

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