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Cocrystal: A Review on the Design and Preparation of Pharmaceutical Cocrystals
Asian Journal of Research in Pharmaceutical Sciences, 2023The majority of the active pharmaceutical components have issues with poor solubility, bioavailability, chemical stability, and moisture absorption. Pharmaceutical crystals are a reliable way to change the aforementioned physicochemical properties of drugs without changing their pharmacological behaviour.
Tanmay Jit +4 more
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Chemistry - A European Journal, 2023
AbstractOrganic spintronics has caused a huge revolution in creating highly efficient low‐power circuits. Spin manipulation in organic cocrystals has become a promising strategy to uncover more chemicophysical properties for diverse applications. In this Minireview, we summarize the recent advancements of spin properties in organic charge‐transfer ...
Yang Li, Zhang Cheng, Qichun Zhang
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AbstractOrganic spintronics has caused a huge revolution in creating highly efficient low‐power circuits. Spin manipulation in organic cocrystals has become a promising strategy to uncover more chemicophysical properties for diverse applications. In this Minireview, we summarize the recent advancements of spin properties in organic charge‐transfer ...
Yang Li, Zhang Cheng, Qichun Zhang
exaly +3 more sources
Pharmaceutical cocrystals: An overview
International Journal of Pharmaceutics, 2011Pharmaceutical cocrystals are emerging as a new class of solid drugs with improved physicochemical properties, which has attracted increased interests from both industrial and academic researchers. In this paper a brief and systematic overview of pharmaceutical cocrystals is provided, with particular focus on cocrystal design strategies, formation ...
Qiao, N. +5 more
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Nutraceutical cocrystals: utilizing pterostilbene as a cocrystal former
CrystEngComm, 2010The nutraceutical compound pterostilbene is investigated for its propensity to form cocrystalline materials with active pharmaceutical ingredients. Three cocrystals of a 1 : 1 stoichiometric molar ratio of pterostilbene with caffeine (two polymorphs, Form I and Form II) and carbamazepine were prepared and characterized by crystallographic (XRPD, single-
Nate Schultheiss +2 more
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Procedia Chemistry, 2014 AbstractCocrystals are very interesting and useful product. In this paper the main information about cocrystals is presented. It is shown that cocrystals are solid substances, which consist of few components mixed together. There are a lot of ways of cocrystals production and application.
Korotkova, Elena Ivanovna +1 more
exaly +3 more sources
Chem. Commun., 2006
The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
Friščić, Tomislav +4 more
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The reaction between pairs of enantiomeric cocrystals involving caffeine or theophylline and a chiral cocrystal former has been investigated by liquid-assisted grinding: we demonstrate two different outcomes for such cocrystal-cocrystal reactions.
Friščić, Tomislav +4 more
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Color-Tunable Upconversion-Emission Switch Based on Cocrystal-to-Cocrystal Transformation
Journal of the American Chemical Society, 2023Cocrystal engineering, involving the assembly of two or more components into a highly ordered solid-state superstructure, has emerged as a popular strategy for tuning the photophysical properties of crystalline materials. The reversible co-assembly and disassembly of multicomponent cocrystals and their reciprocal transformation in the solid state ...
Yu Wang +6 more
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On the thermodynamics of cocrystal formation
International Journal of Pharmaceutics, 2009The thermodynamics underpinning cocrystal formation are derived. The results provide the pharmaceutical scientist with the foundation to experimentally assess the thermodynamic stability of a cocrystal with respect to its component forms. Data for the carbamazepine-nicotinamide system are discussed as an example.
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