Coformer Replacement as an Indicator for Thermodynamic Instability of Cocrystals: Competitive Transformation of Caffeine:Dicarboxylic Acid [PDF]
yesThe thermodynamic stability of caffeine (CA) cocrystals with dicarboxylic acids (DAs) as coformers was investigated in the presence of a range of structurally related dicarboxylic acids (SRDs).
Alsirawan, M.H.D. Bashir +4 more
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Daidzein cocrystals: An opportunity to improve its biopharmaceutical parameters
The present study involves the contribution of cocrystallization towards the modification of the biopharmaceutical parameters of poorly watersoluble plant-originated isoflavone, daidzein (DAID). The cocrystals were prepared with GRAS status coformers i.e.
Yashika Bhalla +3 more
doaj +1 more source
Studies on Cocrystal Formation of Metaxalone with Short-chain Dicarboxylic Acids [PDF]
Hong-Liang Lin +3 more
openalex +1 more source
Innenrücktitelbild: Piezochromic Luminescence of Donor–Acceptor Cocrystals: Distinct Responses to Anisotropic Grinding and Isotropic Compression (Angew. Chem. 48/2018) [PDF]
Yingjie Liu +5 more
openalex +1 more source
Cocrystals of 6-propyl-2-thiouracil: N—H...OversusN—H...S hydrogen bonds [PDF]
M. Tutughamiarso, E. Egert
openalex +1 more source
Ionic Cocrystals of Etiracetam and Levetiracetam: The Importance of Chirality for Ionic Cocrystals
A striking variety of anhydrous and hydrated ionic cocrystals (ICCs) of the enantiopure antiepileptic drug (AED) levetiracetam and of its racemic intermediate etiracetam with the pharmaceutically acceptable salts CaCl2 and MgCl2 was synthesized and structurally characterized.
Lixing Song +5 more
openaire +3 more sources
Apremilast Cocrystals with Phenolic Coformers
Apremilast (APR) is an anti-inflammatory drug commonly used in the treatment of psoriasis. In efforts to enhance its solubility, several cocrystals with similar structural features have been developed. This study investigates the cocrystallization of APR with four phenolic-type coformers: phenol, catechol, pyrogallol, and hydroxyquinol. These coformers
Yelizaveta Naumkina +3 more
openaire +3 more sources
Energetic cocrystals – structural studies of nitrotriazolone salts and cocrystals [PDF]
Hayleigh J. Lloyd +2 more
openaire +1 more source
Insights into antibody catalysis: Structure of an oxygenation catalyst at 1.9-Å resolution [PDF]
The x-ray crystal structures of the sulfide oxidase antibody 28B4 and of antibody 28B4 complexed with hapten have been solved at 2.2-Å and 1.9-Å resolution, respectively.
Hsieh-Wilson, Linda C. +2 more
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