Results 81 to 90 of about 16,055 (257)
Photochromism‐Driven Full Solar Spectrum Absorption for Efficient Photo‐Thermo‐Electric Conversion
Advanced Science, EarlyView.After electron‐transfer photochromism, a black viologen‐based organic compound shows full solar spectrum absorption (250–2500 nm) and near‐infrared photothermal conversion efficiency (NIR‐PCE) >60%. Integrated with a thermoelectric generator, it outputs 1.17 V under 4 Suns irradiation, enough to drive a small fan via photo‐thermo‐electric conversion ...
Ning‐Ning Zhang +7 more
wiley +1 more source
Pharmaceutics, 2021 Palbociclib (PAL) is an effective anti-breast cancer drug, but its use has been partly restricted due to poor bioavailability (resulting from extremely low water solubility) and serious adverse reactions.
Chenxin Duan +8 more
doaj +1 more source
Direct measurement of molecular mobility and crystallisation of amorphous pharmaceuticals using terahertz spectroscopy. [PDF]
, 2016 Despite much effort in the area, no comprehensive understanding of the formation and behaviour of amorphous solids has yet been achieved. This severely limits the industrial application of such materials, including drug delivery where, in principle ...
core +2 more sources
Advanced Science, EarlyView.We report, for the first time, an external electric field (EEF) strategy to achieve co‐aggregation of conjugated polymer blends (i.e., poly(3‐butylthiophene) and poly[3,3'''‐dialkyl‐quaterthiophene]s) in the solution and thus their cocrystals in thin films, demonstrating cocrystal‐improved charge mobilities due to the synergy of two components ...
Yanan Guo, Hao Zheng, Juan Peng
wiley +1 more source
Drug-drug cocrystals: Opportunities and challenges
Asian Journal of Pharmaceutical Sciences, 2021 Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost but high reward route to new and better medicines and could improve the physiochemical and biopharmaceutical properties of a medicine by addition of a suitable
Xiaojuan Wang +5 more
doaj +1 more source
A carbamazepine-indomethacin (1:1) cocrystal produced by milling [PDF]
, 2011 An X-ray amorphous mixture of carbamazepine and indomethacin transforms upon annealing to produce a novel 1:1 cocrystal, whose structure has been determined from laboratory powder X-ray diffraction (PXRD ...
Buckton, Graham +6 more
core +1 more source
Beyond Cocrystals: Hierarchical Functional Assemblies via Noncovalent Synthesis
Advanced Science, EarlyView.Non‐covalent interactions (NCIs) drive the formation of organic cocrystals with diverse structures and tunable optoelectronic properties. This review explores the essential factors governing these properties, highlighting how the sequential nucleation of cocrystals leads to the self‐assembly of organic hierarchical structures (OHSs).
Ya‐Nan Zhu +6 more
wiley +1 more source
Chemical Science, 2011 Calculated gas phase molecular electrostatic potential surfaces have been used to identify sets of H-bond donor and H-bond acceptor sites that describe the possible intermolecular interaction sites on the surface of a molecule. The calculated H-bond parameters, αi and βj, were used to estimate interaction site pairing energies in the solid form of the ...
Daniele Musumeci +4 more
openaire +1 more source
Cocrystal Applications in Drug Delivery [PDF]
Pharmaceutics, 2020 Over the past two decades, considerable research efforts in academia and industry have gone into pharmaceutical cocrystals [...]
openaire +3 more sources
Mechanochemical Synthesis of Pharmaceutical Cocrystal Suspensions via Hot Melt Extrusion: Enhancing Cocrystal Yield [PDF]
Molecular Pharmaceutics, 2017 Pharmaceutical cocrystals have attracted increasing attention over the past decade as an alternative way to modify the physicochemical properties and hence improve the bioavailability of a drug, without sacrificing thermodynamic stability. Our previous work has demonstrated the viability of in situ formation of ibuprofen/isonicotinamide cocrystal ...
Shu Li +5 more
openaire +4 more sources