Results 71 to 80 of about 7,051 (200)
Cocrystal Applications in Drug Delivery [PDF]
Pharmaceutics, 2020 Over the past two decades, considerable research efforts in academia and industry have gone into pharmaceutical cocrystals [...]
openaire +3 more sources
Next Generation Hosts for Protein Recognition, Assembly and More
Chemistry – A European Journal, EarlyView.The original design of synthetic receptors for proteins was based on macrocycles with a hydrophobic core and a polar/charged periphery. This design, geared towards protein recognition, facilitates receptor self‐assembly. Macrocycle oligomerization, in turn, contributes to protein assembly as evidenced in many cocrystal structures.
Peter B. Crowley
wiley +1 more source
ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.Gas–solid interface‐assisted growth strategies have unlocked precise control over crystal structure, morphology, dimension, and molecular packing. The obtained organic semiconductor single crystals represent the ideal candidates for high‐performance organic optoelectronic devices.
Tingyi Yan +8 more
wiley +1 more source
Fluconazole Cocrystals with Dicarboxylic Acids
, 2016 Fluconazole cocrystals were prepared with the intention to modify physicochemical properties of the antifungal agent. The well-known COOH···Narom heterosynthon was considered the key element in the cocrystals design strategy.
Primož Šket (1651762) +8 more
core +3 more sources
Propellants, Explosives, Pyrotechnics, EarlyView.Ammonium dinitramide (ADN) and 3,4‐Diaminofurazan (DAF) form a 1:1 energetic cocrystal. We report its crystal structure and spectroscopic signature and evaluate thermal stability, decomposition behavior, hygroscopicity, and combustion properties. Propellant performance calculations benchmark the material against guanylurea dinitramide (GuDN) and ...
Peter Schultz +2 more
wiley +1 more source
Drug-drug cocrystals: Opportunities and challenges
Asian Journal of Pharmaceutical Sciences, 2021 Recently, drug-drug cocrystal attracts more and more attention. It offers a low risk, low-cost but high reward route to new and better medicines and could improve the physiochemical and biopharmaceutical properties of a medicine by addition of a suitable
Xiaojuan Wang +5 more
doaj +1 more source
Boron‐10 carriers and their applications in boron neutron capture therapy
Precision Radiation Oncology, EarlyView.Summary of different types of boron drugs. Abstract Boron neutron capture therapy (BNCT) has emerged as a promising therapeutic modality in cancer treatment, demonstrating the ability to selectively eliminate cancer cells through the 10B(n,α)7Li nuclear reaction with minimal side effects on normal tissues.
Dachao Tang +7 more
wiley +1 more source
Understanding the formation of apremilast cocrystals [PDF]
Acta Crystallographica Section B Structural Science, Crystal Engineering and Materials, 2019 Apremilast (APR), an anti-psoriatic agent, easily forms isostructural cocrystals and solvates with aromatic entities, often disobeying at the same time Kitaigorodsky's rule as to the saturation of possible hydrogen-bonding sites. In this paper the reasons for this peculiar behavior are investigated, employing a joint experimental and theoretical ...
Marta K. Dudek +7 more
openaire +3 more sources
Energy Transfer in Nanodroplet‐Based Luminescent Solar Concentrators
Small, EarlyView.We present novel luminescent solar concentrators (LSCs) featuring polymer composites with fluorescent dye‐doped oil nanodroplets. This liquid environment ensures high dye solubility and preserves fluorescence quantum yields, even at high local dye concentrations.
Lorenzo Vallan +7 more
wiley +1 more source
Scientia PharmaceuticaRosuvastatin calcium is a promising lipid-lowering agent and the drug of choice in hyperlipidemia. Conventional solid oral delivery of rosuvastatin is limited by its poor solubility and ultimately poor bioavailability.
Deepak Kulkarni, Sanjay Pekamwar
doaj +1 more source