Results 21 to 30 of about 21,454 (169)

Content of alkaloids in ornamental Papaver somniferum L. cultivars growing in Estonia; pp. 34–39 [PDF]

Proceedings of the Estonian Academy of Sciences, 2017
The alkaloid content in industrial opium poppies (Papaver somniferum L.) has been studied by numerous authors, but not in ornamental cultivars.The aim of the study was to investigate the content of morphine, codeine, and papaverine in P.
Andres Meos, Liis Saks, Ain Raal
doaj   +1 more source

THE EFFECT OF PARACETAMOL AND CODEINE ANALGESIC COMBINATION ON SERUM GLUTAMIC OXALOACETATE TRANSAMINASE LEVELS IN MALE WISTAR RATS

Jurnal Kedokteran Diponegoro, 2020
Introduction : Paracetamol is an effective analgesic to relieve mild to moderate pain when it is used in therapeutic doses. Codeine is an opioid analgesic to relieve moderate to severe pain. Both are metabolized in the liver and have different mechanisms
Rona Ayu Hanifah, Farah Hendara Ningrum, Erwin Kresnoadi, Satrio Adi Wicaksono   +3 more
doaj   +1 more source

A study of medical professionals’ perspectives on medicines containing codeine in South Africa

South African Journal of Psychiatry, 2018
Background: Misuse of codeine available on prescription and over-the-counter (OTC) has been highlighted as a potential problem in South Africa. Objective: To examine the perceptions of medical professionals regarding codeine use (prescribed and OTC ...
Michelle Foley, Tara Carney, Eileen Rich, Siphokazi Dada, Chrisitne Mburu, Charles Parry   +5 more
doaj   +1 more source

Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis

Redox Report, 2020
Background: Opioids have been implicated to induce infertility. Although codeine remains the most used opioid for recreational purpose, no study has documented its effect on sperm quality.
Ayodeji Folorunso Ajayi, Roland Eghoghosoa Akhigbe   +1 more
doaj   +1 more source

A comparative analysis of pharmacists’ perspectives on codeine use and misuse – a three country survey

Substance Abuse Treatment, Prevention, and Policy, 2018
Background The misuse of codeine is of increasing concern in a number of countries, particularly as this relates to over -the-counter pain and cough relief medication, and is also supplied as a prescription medicine. The study aimed to obtain and analyse
Tara Carney, John Wells, Charles D. H. Parry, Padraig McGuinness, Richard Harris, Marie Claire Van Hout   +5 more
doaj   +1 more source

A Review of Analytical Methods for Codeine Determination

Molecules, 2021
Codeine is derived from morphine, an opioid analgesic, and has weaker analgesic and sedative effects than the parent molecule. This weak opioid is commonly used in combination with other drugs for over-the-counter cough relief medication.
Rimadani Pratiwi, Eka Noviana, Rizky Fauziati, Daniel Blascke Carrão, Firas Adinda Gandhi, Mutiara Aini Majid, Febrina Amelia Saputri   +6 more
doaj   +1 more source

COMPARATIVE STUDY OF PAIN KILLER DRUGS EFFECTS AFTER THE DENTAL IMPLANT PLACEMENT IN THE ACTIVE ADULT POPULATION [PDF]

Romanian Journal of Stomatology, 2019
There is controversy in recent studies on the use of NSAIDs used to control pain and swelling after the insertion of dental implants that may interfere with the osteointegration process.
Ruxandra Nicolette Voinea Georgescu, Cristian Niky Cumpătă, Mihaela Răescu, Mircea Gheorghiţă, Andreea Gabriela Nicola, Dana Cosac   +5 more
doaj   +1 more source

Immunologic Profiling Suggests an Association Between Treg Cell Dysfunction and Pain in Knee Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective Pain is the hallmark symptom of osteoarthritis (OA), and its biologic drivers remain poorly understood. Although the role of innate immunity in OA has been extensively studied, the involvement of adaptive immunity, in particular Treg cells, is not well understood.
Marie Binvignat, Johanna Dubois, Maria Marco Salvador, Paul Stys, Fabien Pitoiset, Alexandra Roux, Michèle Sastre, Signe Hassler, Roberta Lorenzon, Claire Ribet, Vanessa Mhanna, Hélène Vantomme, Leslie Adda, Pierre Barennes, Nicolas Coatnoan, Kenz Le Gouge, Caroline Aheng, Alice Courties, Lise Minssen, Atul J. Butte, Adrien Six, Michelle Rosenzwajg, Nicolas Tchitchek, Francis Berenbaum, David Klatzmann, Encarnita Mariotti‐Ferrandiz, Jérémie Sellam   +26 more
wiley   +1 more source

Drug poisonings following bariatric surgery: Case series report

British Journal of Clinical Pharmacology, EarlyView.
Bariatric surgery alters gastrointestinal anatomy and physiology, which likely impacts upon oral medication absorption. Drug‐ and alcohol‐related deaths in this population are being increasingly reported; however, toxicological detail is lacking. Using data reported to the National Programme on Substance Use Mortality, we identified 18 deaths in people
Eman Mshari, Fannie LaJeunesse‐Trempe, Stephen Morley, Caroline Copeland   +3 more
wiley   +1 more source

Orofacial antinociceptive activity of codeine-associated geraniol in mice: a controlled triple-blind study [PDF]

Brazilian Oral Research
This is a nonclinical, controlled, and triple-blind study to investigate the effects of codeine-associated geraniol on the modulation of orofacial nociception and its potential central nervous system depressing effect in an animal model.
Ana Paula Lopes NUNES, Humberto Hugo Nunes de ANDRADE, Danielle da Nóbrega ALVES, Gleycyelly Rodrigues ARAÚJO, Mirian Graciela da Silva Stiebbe SALVADORI, Reinaldo Nóbrega de ALMEIDA, Ricardo Dias de CASTRO   +6 more
doaj   +1 more source