Results 11 to 20 of about 25,618 (232)

Effect of codeine on CYP450 isoform activity of rats

open access: yesPharmaceutical Biology, 2017
Context: Codeine, also known as 3-methylmorphine, is an opiate used to treat pain, as a cough medicine and for diarrhoea. No study on the effects of codeine on the metabolic capacity of CYP enzyme is reported.
Shuanghu Wang   +8 more
doaj   +2 more sources

Comparison of the postoperative analgesic effects of paracetamol–codeine phosphate and naproxen sodium–codeine phosphate for lumbar disk surgery

open access: yesKaohsiung Journal of Medical Sciences, 2015
The aim of this study was to compared the efficacy of paracetamol–codeine phosphate and naproxen sodium–codeine phosphate on postoperative pain and tramadol consumption during the first 24 hours after a lumbar disk surgery.
Reyhan Polat   +4 more
doaj   +2 more sources

A Novel PbS Nanparticle Based Electrochemical Codeine Sensor

open access: yesMATEC Web of Conferences, 2016
In the present study, we describe an electrochemical sensor for codeine detection by using the DNA aptamers against codeine. In the sensing protocol, a dually-labeled DNA Aptamer probe was designed to belabeled at one end with HS, and at its another end ...
Peng Hong   +4 more
doaj   +3 more sources

Methods of forensic examination of codeine in combination drugs

open access: yesBulletin of Kharkiv National University of Internal Affairs
The article addresses the peculiarities of forensic examination of codeine in the composition of combination drugs i.e. the prescription drugs that are available in many pharmacies without a prescription.
I. O. Besedina
doaj   +2 more sources

Impact of Removing Nonprescription Codeine in Australia: Protocol for a Prospective Cohort Study

open access: yesJMIR Research Protocols, 2020
BackgroundOn February 1, 2018, Australia rescheduled codeine to a prescription-only medication. Many concerns were associated with this change, including increased financial costs, reduced service accessibility, the potential for poorer pain management ...
McCoy, Jacqui   +2 more
doaj   +1 more source

Effects of the FDA Codeine Safety Investigation on Racial and Geographic Disparities in Opioid Prescribing after Pediatric Tonsillectomy and/or Adenoidectomy

open access: yesGlobal Pediatric Health, 2021
Objective. Our objective was to examine the impact of the U.S. FDA’s 2013 black box warning against codeine on codeine and other opioid prescription filling after pediatric tonsillectomy and/or adenoidectomy (T/A) overall and by child race and provider ...
Amy Lawrence   +5 more
doaj   +1 more source

Apoptotic inducement of neuronal cells by codeine: possible role of disrupted redox state and caspase 3 signaling

open access: yesHeliyon, 2021
Background: Codeine, a common drug of abuse, has been reported to induce organ damage; however, there are scanty available data on the effects of codeine on the brain. Objective: Thus, we tested the hypothesis that redox dysregulation and inflammation of
A.F. Ajayi, R.E. Akhigbe
doaj   +1 more source

The importance of 6-MAM levels and morphine/codeine ratio in diagnosis of death among drug addicts [PDF]

open access: yesSrpski Arhiv za Celokupno Lekarstvo, 2019
Introduction/Objective. Heroin is metabolized to 6-monoacetylmorphine (6-MAM) and morphine. The objective of this study is to examine 6-MAM, morphine, and codeine relationships in order to distinguish deaths related to heroin consumption from deaths ...
Jakšić Vladimir   +5 more
doaj   +1 more source

A clinical tool for reducing central nervous system depression among neonates exposed to codeine through breast milk. [PDF]

open access: yesPLoS ONE, 2013
Neonates are commonly exposed to maternal codeine through breast milk. Central Nervous System (CNS) depression has been reported in up to 24% of nurslings following codeine exposure.
Lauren E Kelly   +11 more
doaj   +1 more source

Opium trade and use during the Late Bronze Age: Organic residue analysis of ceramic vessels from the burials of Tel Yehud, Israel

open access: yesArchaeometry, EarlyView., 2022
Abstract Organic residue analysis was conducted on various vessels from burials at Tel Yehud, Israel. The analyses led to new reliable evidence for the presence of opioid alkaloids and their decomposition products. This research revitalizes a decades‐old discussion on the presence and function of the opium trade across a cultural region of utmost ...
Vanessa Linares   +5 more
wiley   +1 more source

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