Results 41 to 50 of about 27,730 (240)

A comparative analysis of pharmacists’ perspectives on codeine use and misuse – a three country survey

Substance Abuse Treatment, Prevention, and Policy, 2018
Background The misuse of codeine is of increasing concern in a number of countries, particularly as this relates to over -the-counter pain and cough relief medication, and is also supplied as a prescription medicine. The study aimed to obtain and analyse
Tara Carney, John Wells, Charles D. H. Parry, Padraig McGuinness, Richard Harris, Marie Claire Van Hout   +5 more
doaj   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Inhibition of Brain CYP2D Lowers Codeine-induced Analgesia in Rats [PDF]

, 2012
CYP2D6 metabolizes codeine to morphine, the active analgesic metabolite. Variation in brain CYP2D6 activity may affect brain morphine levels after codeine administration and thereby influence analgesia. We investigate the effect of inhibiting brain CYP2D
Zhou, Kaidi
core   +2 more sources

Functional phenotyping of the CYP2D6 probe drug codeine in the horse

BMC Veterinary Research, 2021
Background In humans, the drug metabolizing enzyme CYP2D6 is highly polymorphic resulting in substantial differences in the metabolism of drugs including anti-arrhythmics, neuroleptics, and opioids.
S. R. Gretler, C. J. Finno, P. H. Kass, H. K. Knych   +3 more
doaj   +1 more source

Codeine versus placebo for chronic cough in children

, 2015
This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the safety and efficacy of codeine (and derivatives) for the treatment of chronic cough in ...
Anne B Chang, Gardiner, SJ, Petsky, HL, Gardiner, Samantha J., Chang, Anne B., Samantha J Gardiner, Helen L Petsky, Petsky, Helen L., Chang, AB   +8 more
core   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

Cough, codeine and confusion.

, 2015
Codeine is widely prescribed in clinical practice with over the counter (OTC) preparations of codeine freely available for consumption typically as a component of remedies for the common cold/cough.
O Reilly, David, Thomas, Mathew, Moylett, Edina   +2 more
core   +1 more source

The impact of pharmacogenetic‐informed care on medication adherence and psychological factors associated with adherence: A narrative review

British Journal of Clinical Pharmacology, EarlyView.
Improvement in medication adherence is often proposed as a potential advantage of pharmacogenetic‐guided prescribing over a traditional one‐size‐fits‐all approach. This paper provides a review of the published literature and presents the findings of studies that measure adherence to medication as an outcome of pharmacogenetic‐informed care, or that ...
Lucy Galloway, Alison Wright, John Weinman   +2 more
wiley   +1 more source

Preventing another Codeine debacle? Pharmacist management of analgesia [PDF]

, 2017
The announcement that OTC codeine-containing products will be up-scheduled to Prescription Only in 2018 may have come as a surprise to many pharmacists. However, rather than simply bemoaning the decision, we should look at how, as a profession, we might ...
Hall, Tony, Lau, Esther, Nissen, Lisa
core  

Opportunities and challenges: Over-the-counter codeine supply from the codeine consumer's perspective

, 2013
Objectives: This study aimed to gain a better understanding on perspectives of over-the-counter (OTC) codeine users and issues relating to codeine dependence in the community pharmacy setting.
Pahoki, S, Nielsen, S ; https://orcid.org/, Cameron, J   +2 more
core   +1 more source