Results 31 to 40 of about 25,618 (232)

Inside codeine crisis in Ireland as demand for drug used to treat addiction almost quadruples in five years.

, 2022
Demand for a drug used to treat codeine addiction has almost quadrupled over the past five years (The drug — which can also treat other opioid addictions such as heroin). But one expert told The Irish Sun on Sunday: “The codeine ­problem is undertreated.
Farrell, Craig, Higgins, Adam
core  

Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis

Redox Report, 2020
Background: Opioids have been implicated to induce infertility. Although codeine remains the most used opioid for recreational purpose, no study has documented its effect on sperm quality.
Ayodeji Folorunso Ajayi, Roland Eghoghosoa Akhigbe   +1 more
doaj   +1 more source

A comparative analysis of pharmacists’ perspectives on codeine use and misuse – a three country survey

Substance Abuse Treatment, Prevention, and Policy, 2018
Background The misuse of codeine is of increasing concern in a number of countries, particularly as this relates to over -the-counter pain and cough relief medication, and is also supplied as a prescription medicine. The study aimed to obtain and analyse
Tara Carney, John Wells, Charles D. H. Parry, Padraig McGuinness, Richard Harris, Marie Claire Van Hout   +5 more
doaj   +1 more source

COMPARATIVE STUDY OF PAIN KILLER DRUGS EFFECTS AFTER THE DENTAL IMPLANT PLACEMENT IN THE ACTIVE ADULT POPULATION [PDF]

Romanian Journal of Stomatology, 2019
There is controversy in recent studies on the use of NSAIDs used to control pain and swelling after the insertion of dental implants that may interfere with the osteointegration process.
Ruxandra Nicolette Voinea Georgescu, Cristian Niky Cumpătă, Mihaela Răescu, Mircea Gheorghiţă, Andreea Gabriela Nicola, Dana Cosac   +5 more
doaj   +1 more source

A prospective series of acute rivaroxaban overdose, coagulopathy and bleeding complications (ATOM 11)

British Journal of Clinical Pharmacology, EarlyView.
Aim There is limited research describing rivaroxaban overdose. We aim to describe rivaroxaban overdose, coagulopathy and bleeding complications. Methods This is a prospective series of acute adult (>14 years) rivaroxaban overdose presentations >40 mg enrolled in the Australian Toxicology Monitoring study and presenting to three Australian clinical ...
Katherine Z. Isoardi, Angela L. Chiew, Keith Harris, Geoffrey K. Isbister   +3 more
wiley   +1 more source

Orofacial antinociceptive activity of codeine-associated geraniol in mice: a controlled triple-blind study [PDF]

Brazilian Oral Research
This is a nonclinical, controlled, and triple-blind study to investigate the effects of codeine-associated geraniol on the modulation of orofacial nociception and its potential central nervous system depressing effect in an animal model.
Ana Paula Lopes NUNES, Humberto Hugo Nunes de ANDRADE, Danielle da Nóbrega ALVES, Gleycyelly Rodrigues ARAÚJO, Mirian Graciela da Silva Stiebbe SALVADORI, Reinaldo Nóbrega de ALMEIDA, Ricardo Dias de CASTRO   +6 more
doaj   +1 more source

Spray‐Dried Engineered Escherichia coli Whole‐Cell Biocatalysts Enable Cell Recycling and In Vivo α‐Ketoglutarate and NADPH Regeneration for Efficient Codeine Manufacture

Biotechnology and Bioengineering, EarlyView.
ABSTRACT A recombinant whole‐cell biocatalytic approach provides several advantages over isolated enzymes, such as improved enzyme stability, in vivo cofactor regeneration, and the facilitation of cascade reactions within a single cell. Whole‐cell biocatalysis has gained attention in medicinal opioid production, due to its technical and economic ...
Ali Jahanian, Carlos Horacio Luna‐Flores, Xu Li, Sally L. Gras, Robert E. Speight   +4 more
wiley   +1 more source

Codeine versus placebo for chronic cough in children

, 2015
This is the protocol for a review and there is no abstract. The objectives are as follows: To evaluate the safety and efficacy of codeine (and derivatives) for the treatment of chronic cough in ...
Anne B Chang, Gardiner, SJ, Petsky, HL, Gardiner, Samantha J., Chang, Anne B., Samantha J Gardiner, Helen L Petsky, Petsky, Helen L., Chang, AB   +8 more
core   +1 more source

Patient‐ and Clinician‐Related Factors Associated With the Reduction in Opioid Use Among Adults With Chronic Non‐Cancer Pain: A Systematic Review

Clinical Pharmacology &Therapeutics, EarlyView.
Despite known risks, opioids are widely used for chronic non‐cancer pain (CNCP). Clinical guidelines now recommend deprescribing, but factors predicting success are poorly understood. This systematic review aimed to identify clinician and patient factors associated with attaining successful opioid dose reduction or discontinuation in adults with CNCP ...
Alessandra C. Marcelo, Sarah N. Hilmer, David J. Hunter, Stephanie Mathieson, Riyaas Mohamed, Leo Li, Natalie Fung, Anthony Yue, Manuela L. Ferreira   +8 more
wiley   +1 more source

Cough, codeine and confusion.

, 2015
Codeine is widely prescribed in clinical practice with over the counter (OTC) preparations of codeine freely available for consumption typically as a component of remedies for the common cold/cough.
O Reilly, David, Thomas, Mathew, Moylett, Edina   +2 more
core   +1 more source