Results 31 to 40 of about 27,730 (240)

Content of alkaloids in ornamental Papaver somniferum L. cultivars growing in Estonia; pp. 34–39 [PDF]

Proceedings of the Estonian Academy of Sciences, 2017
The alkaloid content in industrial opium poppies (Papaver somniferum L.) has been studied by numerous authors, but not in ornamental cultivars.The aim of the study was to investigate the content of morphine, codeine, and papaverine in P.
Andres Meos, Liis Saks, Ain Raal
doaj   +1 more source

Orofacial antinociceptive activity of codeine-associated geraniol in mice: a controlled triple-blind study [PDF]

Brazilian Oral Research
This is a nonclinical, controlled, and triple-blind study to investigate the effects of codeine-associated geraniol on the modulation of orofacial nociception and its potential central nervous system depressing effect in an animal model.
Ana Paula Lopes NUNES, Humberto Hugo Nunes de ANDRADE, Danielle da Nóbrega ALVES, Gleycyelly Rodrigues ARAÚJO, Mirian Graciela da Silva Stiebbe SALVADORI, Reinaldo Nóbrega de ALMEIDA, Ricardo Dias de CASTRO   +6 more
doaj   +1 more source

Codeine-induced sperm DNA damage is mediated predominantly by oxidative stress rather than apoptosis

Redox Report, 2020
Background: Opioids have been implicated to induce infertility. Although codeine remains the most used opioid for recreational purpose, no study has documented its effect on sperm quality.
Ayodeji Folorunso Ajayi, Roland Eghoghosoa Akhigbe   +1 more
doaj   +1 more source

Inside codeine crisis in Ireland as demand for drug used to treat addiction almost quadruples in five years.

, 2022
Demand for a drug used to treat codeine addiction has almost quadrupled over the past five years (The drug — which can also treat other opioid addictions such as heroin). But one expert told The Irish Sun on Sunday: “The codeine ­problem is undertreated.
Farrell, Craig, Higgins, Adam
core  

Alcohol consumption in heroin users, methadone-substituted and codeine-substituted patients - Frequency and correlates of use [PDF]

, 2003
This retrospective study aims to determine whether there is a difference in the additional consumption of alcohol between addicts treated with methadone or dihydrocodeine (DHC) and untreated addicts injecting heroin.
Schütz, Christian G., Backmund, Markus, Soyka, Michael, Eichenlaub, Dieter, Meyer, Kirsten   +4 more
core   +1 more source

Impact of a policy change restricting access to codeine on prescription opioid-related emergency department presentations: an interrupted time series analysis

, 2020
: Codeine is one of the most commonly used opioid analgesics. Significant codeine-related morbidity and mortality prompted regulatory responses, with the up-scheduling of codeine combination analgesics to prescription-only medicines implemented in ...
Gary Chan, Rachel A. Elphinston, Freeman, Chris, Linda Hipper, Elphinston, Rachel A, Sterling, Michele, Chris Freeman, de Andrade, Dominique, Connor, Jason P, Dominique de Andrade, Hipper, Linda, Chan, Gary, Michele Sterling, Jason P. Connor   +13 more
core   +1 more source

Relationship Between Severe Respiratory Depression and Codeine-Containing Antitussives in Children: A Nested Case-Control Study

Journal of Epidemiology, 2020
Background: Guidelines recommend against all codeine use in children for its common indications of analgesia and cough suppression because of uncertain benefits and potential risk of death.
Sachiko Ono, Yosuke Ono, Daisuke Koide, Hideo Yasunaga   +3 more
doaj   +1 more source

Opioid Allergy Registrations in Danish Electronic Health Records: A Multihospital Register-Based Study With Journal Audit. [PDF]

Basic Clin Pharmacol Toxicol
ABSTRACT Accurate documentation of drug allergies is critical to prevent re‐exposure while avoiding unnecessary restrictions on safe pharmacotherapy. Although true opioid hypersensitivity is rare, adverse effects are frequently misclassified as allergies.
Eiset AH, Hansen SH, Rosenquist SB, Skov K, Garvey LH, Uhrbrand PG, Sædder EA.   +6 more
europepmc   +2 more sources

Precision medicine in paediatrics: Progress and priorities

British Journal of Clinical Pharmacology, EarlyView.
Precision medicine is revolutionizing personalized healthcare, advancing both diagnostics and therapeutics at an unprecedented pace. Reviewing the paediatric applications of pharmacometrics, pharmacogenomics and advanced therapy medicinal products highlights not only the relevance of these exciting innovations to frontline care but also the significant
Nicola Husain, Claire Booth, Joseph F. Standing, Charlotte I. S. Barker   +3 more
wiley   +1 more source

A New Sensitive Sensor for Simultaneous Differential Pulse Voltammetric Determination of Codeine and Acetaminophen Using a Hydroquinone Derivative and Multiwall Carbon Nanotubes Carbon Paste Electrode

International Journal of Analytical Chemistry, 2015
A new sensitive sensor was fabricated for simultaneous determination of codeine and acetaminophen based on 4-hydroxy-2-(triphenylphosphonio)phenolate (HTP) and multiwall carbon nanotubes paste electrode at trace levels.
Elahe Garazhian, M. Reza Shishehbore
doaj   +1 more source