Results 21 to 30 of about 25,618 (232)

Trends and characteristics of accidental and intentional codeine overdose deaths in Australia [PDF]

, 2015
Examines trends in codeine-related mortality rates in Australia, and the clinical and toxicological characteristics of codeine-related deaths. Abstract Objectives: To examine trends in codeine-related mortality rates in Australia, and the clinical and ...
Pilgrim, Jennifer, Hall, WD ; https://orcid.org/, Amanda Roxburgh, Saar, E, Nielsen, Suzanne, Hall, Wayne D., Degenhardt, L ; https://orcid.org/, Jennifer Pilgrim, Louisa Degenhardt, Eva Saar, Pilgrim, J, Lucinda Burns, Degenhardt, Louisa, Nielsen, S ; https://orcid.org/, Roxburgh, A ; https://orcid.org/, Suzanne Nielsen, Burns, L ; https://orcid.org/, Wayne D Hall, Roxburgh, Amanda, Burns, Lucinda, Saar, Eva   +20 more
core   +1 more source

Spatial clustering of codeine use and its association with depression: a geospatial analysis of nationally representative South African data

Journal of Affective Disorders Reports, 2022
Background: There is an alarming trend in sub-Saharan Africa in the use of codeine-containing pharmaceuticals, but its risk of common comorbidities, such as mental health, remains unquantified at a national-level. We investigated the relationship between
Princess Nyoni, Diego F. Cuadros, Andrew Gibbs, Frank Tanser, Rob Slotow, Jonathan K Burns, Andrew Tomita   +6 more
doaj   +1 more source

A Single Site Population Study to Investigate CYP2D6 Phenotype of Patients with Persistent Non-Malignant Pain

Medicina, 2019
Background and Objectives: Codeine requires biotransformation by the CYP2D6 enzyme, encoded by the polymorphic CYP2D6 gene, to morphine for therapeutic efficacy. CYP2D6 phenotypes of poor, intermediate, and ultra-rapid metabolisers are at risk of codeine
Helen Radford, Karen H. Simpson, Suzanne Rogerson, Mark I. Johnson   +3 more
doaj   +1 more source

Cocrystal of Codeine and Cyclopentobarbital

, 2023
The two-component compound formed by codeine and cyclopentobarbital was produced using grinding techniques and through evaporation from alcoholic solutions.
Thomas Gelbrich, Ulrich J. Griesser, Jascha Schinke   +2 more
core   +1 more source

Resolving Issues About Efficacy and Safety of Low-Dose Codeine in Combination Analgesic Drugs: A Systematic Review

Pain and Therapy, 2020
Introduction The objective of this systematic review is to reflect on assumptions in relation to codeine use in combination with other analgesics. Methods MEDLINE was searched according to the predetermined keywords and criteria.
Ivan Ćelić, Lidija Bach-Rojecky, Iveta Merćep, Ana Soldo, Anja Kos Petrak, Ana Bučan   +5 more
doaj   +1 more source

Alcohol consumption in heroin users, methadone-substituted and codeine-substituted patients - Frequency and correlates of use [PDF]

, 2003
This retrospective study aims to determine whether there is a difference in the additional consumption of alcohol between addicts treated with methadone or dihydrocodeine (DHC) and untreated addicts injecting heroin.
Schütz, Christian G., Backmund, Markus, Soyka, Michael, Eichenlaub, Dieter, Meyer, Kirsten   +4 more
core   +1 more source

Content of alkaloids in ornamental Papaver somniferum L. cultivars growing in Estonia; pp. 34–39 [PDF]

Proceedings of the Estonian Academy of Sciences, 2017
The alkaloid content in industrial opium poppies (Papaver somniferum L.) has been studied by numerous authors, but not in ornamental cultivars.The aim of the study was to investigate the content of morphine, codeine, and papaverine in P.
Andres Meos, Liis Saks, Ain Raal
doaj   +1 more source

THE EFFECT OF PARACETAMOL AND CODEINE ANALGESIC COMBINATION ON SERUM GLUTAMIC OXALOACETATE TRANSAMINASE LEVELS IN MALE WISTAR RATS

Jurnal Kedokteran Diponegoro, 2020
Introduction : Paracetamol is an effective analgesic to relieve mild to moderate pain when it is used in therapeutic doses. Codeine is an opioid analgesic to relieve moderate to severe pain. Both are metabolized in the liver and have different mechanisms
Rona Ayu Hanifah, Farah Hendara Ningrum, Erwin Kresnoadi, Satrio Adi Wicaksono   +3 more
doaj   +1 more source

A study of medical professionals’ perspectives on medicines containing codeine in South Africa

South African Journal of Psychiatry, 2018
Background: Misuse of codeine available on prescription and over-the-counter (OTC) has been highlighted as a potential problem in South Africa. Objective: To examine the perceptions of medical professionals regarding codeine use (prescribed and OTC ...
Michelle Foley, Tara Carney, Eileen Rich, Siphokazi Dada, Chrisitne Mburu, Charles Parry   +5 more
doaj   +1 more source

Impact of a policy change restricting access to codeine on prescription opioid-related emergency department presentations: an interrupted time series analysis

, 2020
: Codeine is one of the most commonly used opioid analgesics. Significant codeine-related morbidity and mortality prompted regulatory responses, with the up-scheduling of codeine combination analgesics to prescription-only medicines implemented in ...
Gary Chan, Rachel A. Elphinston, Freeman, Chris, Linda Hipper, Elphinston, Rachel A, Sterling, Michele, Chris Freeman, de Andrade, Dominique, Connor, Jason P, Dominique de Andrade, Hipper, Linda, Chan, Gary, Michele Sterling, Jason P. Connor   +13 more
core   +1 more source