Results 31 to 40 of about 69,133 (285)

Scaling laws in bacterial genomes: A side-effect of selection of mutational robustness? [PDF]

open access: yes, 2010
In the past few years, numerous research projects have focused on identifying and understanding scaling properties in the gene content of prokaryote genomes and the intricacy of their regulation networks.
Adami   +37 more
core   +4 more sources

Constructing ORFeome resources with removable termination codons

open access: yesBioTechniques, 2006
The Return of the Native Some of the most widely used ORF resource clones dispense with native termination codons.
Masayoshi Itoh   +8 more
openaire   +3 more sources

Consolidated bioprocessing of starchy substrates into ethanol by industrial Saccharomyces cerevisiae strains secreting fungal amylases [PDF]

open access: yes, 2015
The development of a yeast strain that converts raw starch to ethanol in one step (called Consolidated Bioprocessing, CBP) could significantly reduce the commercial costs of starch-based bioethanol. An efficient amylolytic Saccharomyces cerevisiae strain
Abdel-Aal   +45 more
core   +1 more source

Human leukocyte antigen-A*24:02-B*40:247-C*03:04-DRB1*16:02, a deduced probable human leukocyte antigen haplotype associated with a low-incidence human leukocyte antigen allele B*40:247 in Taiwanese individuals: A case analysis

open access: yesTzu Chi Medical Journal, 2018
Objective: HLA-B*40:247 is a low incidence allele in the HLA-B locus. The aim of this study is to confirm the ethnicity of B*40:247 and its deduced probable HLA- associated haplotype in Taiwanese individuals.
Kuo-Liang Yang   +2 more
doaj   +1 more source

CRISPR-Cas9 Toolkit for Genome Editing in an Autotrophic CO2-Fixing Methanogenic Archaeon

open access: yesMicrobiology Spectrum, 2022
The CRISPR-Cas9 system is a robust genome editing tool that is widely applied in eukaryotes and bacteria. However, use of this technique has only been developed for one species of Archaea, a domain of life ranking in parallel with Eukarya and Bacteria ...
Jie Li   +6 more
doaj   +1 more source

Rapid Hypothesis Testing in Candida albicans Clinical Isolates Using a Cloning-Free, Modular, and Recyclable System for CRISPR-Cas9 Mediated Mutant and Revertant Construction

open access: yesMicrobiology Spectrum, 2022
As increasing evidence emerges that interstrain genetic diversity among Candida albicans clinical isolates underpins phenotypic variation compared to the reference isolate SC5314, new genetic tools are required to interrogate gene function across strain ...
Junyan Liu   +6 more
doaj   +1 more source

Tobramycin is a suppressor of premature termination codons [PDF]

open access: yesJournal of Cystic Fibrosis, 2013
Premature translation terminations (PTCs) constitute the molecular basis of many genetic diseases, including cystic fibrosis, as they lead to the synthesis of truncated non-functional or partially functional protein. Suppression of translation terminations at PTCs (read-through) has been developed as a therapeutic strategy to restore full-length ...
Altamura N   +8 more
openaire   +3 more sources

The Novel Anaerobiosis-Responsive Overlapping Gene ano Is Overlapping Antisense to the Annotated Gene ECs2385 of Escherichia coli O157:H7 Sakai

open access: yesFrontiers in Microbiology, 2018
Current notion presumes that only one protein is encoded at a given bacterial genetic locus. However, transcription and translation of an overlapping open reading frame (ORF) of 186 bp length were discovered by RNAseq and RIBOseq experiments. This ORF is
Sarah M. Hücker   +6 more
doaj   +1 more source

The deduced probable HLA-C*03:187-associated human leukocyte antigen haplotype (A*24:02-B*35:01-C*03:187-DRB1*11:01) revealed in Taiwanese unrelated hematopoietic bone marrow stem cell donors

open access: yesTzu Chi Medical Journal, 2020
Objective: HLA-C*03:187 is a rare frequency allele in the human leukocyte antigen (HLA)-C locus. The purpose of this investigation is to indicate the ethnicity of C*03:187 and its deduced plausible HLA haplotype in association in Taiwanese unrelated bone
Kuo-Liang Yang, Py-Yu Lin
doaj   +1 more source

Regulation of PI-2b Pilus Expression in Hypervirulent Streptococcus agalactiae ST-17 BM110. [PDF]

open access: yesPLoS ONE, 2017
The widely spread Streptococcus agalactiae (also known as Group B Streptococcus, GBS) "hypervirulent" ST17 clone is strongly associated with neonatal meningitis.
Bruno Périchon   +8 more
doaj   +1 more source

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