Results 81 to 90 of about 9,001 (100)
Some of the next articles are maybe not open access.
Tandem Stop Codons in Ciliates That Reassign Stop Codons
Journal of Molecular Evolution, 2009Tandem stop codons are extra stop codons hypothesized to be present downstream of genes to act as a backup in case of read-through of the real stop codon. Although seemingly absent from Escherichia coli, recent studies have confirmed the presence of such codons in yeast.
Andre R. O. Cavalcanti, Marie Adachi
openaire +3 more sources
An effect of codon context on the mistranslation of UGU codons in vitro
Journal of Molecular Biology, 1984Effects of codon context on nonsense codon suppression may act either through release factor recognition of termination codons or aminoacyl-tRNA selection by the ribosome. The latter hypothesis has been studied by comparing misreading by Escherichia coli UGA suppressor tryptophan tRNA of UGU (cysteine) codons in two synthetic polymers, poly(U-G) and ...
M.J. Carrier, R.H. Buckingham
openaire +3 more sources
Identification of the UUG codon as a translational initiation codon in vivo
Journal of Molecular Biology, 1975Abstract The lac repressor protein was purified from an Escherichia coli strain carrying an amber mutation in the lacI gene and the tyrosine-inserting amber suppressor, Su3. Protein sequencing showed a change at position 62 in the repressor polypeptide chain from leucine to tyrosine, proving that the amber was derived from a UUG codon at this ...
James G. Files +3 more
openaire +3 more sources
Writing Scrapie's Coda, Codon by Codon?
Science, 2000Over the past decade, geneticists have found that different variations, or polymorphisms, in the gene coding for PrP--a cellular protein that many scientists believe becomes infectious when it converts to an abnormal form called a prion--seem to confer varying degrees of susceptibility to scrapie.
openaire +2 more sources
Initiator Codons in Eukaryotes
Nature, 1970A unique interaction between eukaryotic Met-tRNAF*, AUG and 80S ribosomes is demonstrated. It is suggested that tRNAF*Met is the only initiator tRNA on 80S ribosomes and that AUG and possibly GUG are the initiator codons.
A. E. Smith, Jay C. Brown
openaire +3 more sources
Codon preference in Corynebacteria
Gene, 1993The codon usage (CU) of 34 genes from the closely related species, Brevibacterium lactofermentum and Corynebacterium glutamicum (BLCG), was analysed and compared with that of 23 genes from other Brevibacterium and Corynebacterium species. The G+C content of the BLCG genes ranged from 50 to 62%. A wider range was found in other corynebacterial genes (25-
José A. Gil +2 more
openaire +3 more sources
Biosystems, 1989
For the first time it is shown that each of the three codon bases has a general correlation with a different, predictable amino acid property, depending on position within the codon. In addition to the previously recognized link between the mid-base and the hydrophobic-hydrophilic spectrum, we show that, with the exception of G, the first base is ...
David Coates, F.J.R. Taylor
openaire +3 more sources
For the first time it is shown that each of the three codon bases has a general correlation with a different, predictable amino acid property, depending on position within the codon. In addition to the previously recognized link between the mid-base and the hydrophobic-hydrophilic spectrum, we show that, with the exception of G, the first base is ...
David Coates, F.J.R. Taylor
openaire +3 more sources
Journal of Basic Microbiology, 1986
AbstractCodon usage was analysed for 14 streptococcal genes or significant open reading frames and found to be different from that in Escherichia coli and Bacillus subtilis. In particular, the preferred use of WWT codons over WWC was inconsistent with the rule of optimal codon‐anticodon interaction energy.
openaire +3 more sources
AbstractCodon usage was analysed for 14 streptococcal genes or significant open reading frames and found to be different from that in Escherichia coli and Bacillus subtilis. In particular, the preferred use of WWT codons over WWC was inconsistent with the rule of optimal codon‐anticodon interaction energy.
openaire +3 more sources
Computational Biology and Chemistry, 2007
We develop here an analytical evolution model based on a trinucleotide mutation matrix 64x64 with nine substitution parameters associated with the three types of substitutions in the three trinucleotide sites and with non-zero elements on its main diagonal.
openaire +3 more sources
We develop here an analytical evolution model based on a trinucleotide mutation matrix 64x64 with nine substitution parameters associated with the three types of substitutions in the three trinucleotide sites and with non-zero elements on its main diagonal.
openaire +3 more sources
On Codon-Anticodon Interactions
1980One of the milestones on the road to the discovery of protein biosynthesis pathway was the demonstration by Lipmann’s group that the tRNA’s bring the aminoacids at the proper place on the template, that genetic information is read by tRNA’s (Chapeville et al. 1962).
H. Grosjean, H. Chantrenne
openaire +3 more sources