Results 191 to 200 of about 95,678 (274)
Codon stabilization coefficient as a metric to gain insights into mRNA stability and codon bias and their relationships with translation. [PDF]
Nucleic Acids Res, 2019 Carneiro RL +4 more
europepmc +1 more source
Serial Spatial Transcriptomes Reveal Regulatory Transitions in Maize Leaf Development
Plant Biotechnology Journal, EarlyView.ABSTRACT Plant leaves originate from the shoot apical meristem (SAM) and undergo a developmental process of highly coordinated gene expression regulation. To date, only a few key regulators have been identified and characterised, so the gene expression cascades responsible for leaf cell specification and differentiation from SAM remain largely elusive.
Chi‐Chih Wu +11 more
wiley +1 more source
Elongator and codon bias regulate protein levels in mammalian peripheral neurons. [PDF]
Nat Commun, 2018 Goffena J +9 more
europepmc +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Fusarium wilt of banana (FWB), caused by Fusarium oxysporum f. sp. cubense (Foc), threatens global banana production. Lignin reinforces cell walls against pathogens and lodging, yet its regulatory mechanisms in banana remain elusive. Through genome‐wide association study (GWAS) of lignin content across 184 banana accessions, we identified ...
Yuqi Li +16 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT A key challenge for the genetic improvement of canola (Brassica napus), one of the world's most important oilseeds, is the limited natural variation for commercially important traits. The creation of new variation is hindered by the lack of functional knowledge about genes controlling these traits.
Morgan W. Kirzinger +30 more
wiley +1 more source
Lifestyle modifications: coordinating the tRNA epitranscriptome with codon bias to adapt translation during stress responses. [PDF]
Genome Biol, 2018 Chan C, Pham P, Dedon PC, Begley TJ.
europepmc +1 more source
Transcription Profiling of Potato Leaves in Response to Heat Stress at Single‐Cell Resolution
Plant Biotechnology Journal, EarlyView.ABSTRACT Potato (Solanum tuberosum L.) is a globally important food crop with considerable nutritional and economic value. Heat stress significantly inhibits potato plant growth and tuber development, constraining the sustainable development of the potato industry. Currently, studies on the cellular‐level mechanisms underlying heat adaptation in potato
Shiqi Wen +8 more
wiley +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Forward genetics has been instrumental in identifying genes underlying desirable traits, yet its application to polyploid plants, many of which are key agricultural crops, remains challenging due to their genomic complexity. Therefore, we developed BenthMap, a bulk segregant analysis platform for high‐throughput trait mapping and gene ...
Zuba Ahmed +5 more
wiley +1 more source
Codon bias imposes a targetable limitation on KRAS-driven therapeutic resistance. [PDF]
Nat Commun, 2017 Ali M +7 more
europepmc +1 more source
Plant Biotechnology Journal, EarlyView.ABSTRACT Protoberberine alkaloids are a characteristic group of natural products in Coptis plants known for their notable pharmacological activities. However, the structural similarity and the substrate promiscuity of their biosynthetic enzymes have left the precise synthetic pathways remain unclarified, posing challenges to regulate product formation.
Jun Song +14 more
wiley +1 more source