Results 201 to 210 of about 49,031 (262)

Recombinant Monoclonal Antibodies for Detecting the Tubulin Post‐Translational Modifications Glutamylation and Lysine‐40 Acetylation

Cytoskeleton, EarlyView.
ABSTRACT Post‐translational modifications (PTMs) to tubulin subunits in microtubule filaments are thought to comprise a component of the tubulin code that specifies microtubule functions in cell physiology and animal development. Acetylation of Lysine‐40 (K40) on α‐tubulin (αTub‐K40ac) and glutamylation of both α‐ and β‐tubulin are two tubulin PTMs of ...
Lynne Blasius, Ezekiel C. Thomas, Erik H. Collet, Erin Jenson, Chad G. Pearson, Ryoma Ohi, Kristen J. Verhey   +6 more
wiley   +1 more source

Codon usage modulates the relationship between the burden and yield of protein overexpression. [PDF]

J Biol Eng
Roots CT, Hill AM, Wilke CO, Barrick JE.
europepmc   +1 more source

In Vivo Cytoskeletal AMPA Receptor Transport Imaging in C. elegans

Cytoskeleton, EarlyView.
ABSTRACT Long‐distance intracellular transport of ionotropic glutamate receptors (iGluRs) is essential for proper excitatory synaptic function underlying learning and memory. Many neuropsychiatric and neurodegenerative conditions have abnormal iGluR transport and trafficking, leading to an intense interest in the mechanisms and factors regulating these
Michaelis A. K., Hoerndli F. J.
wiley   +1 more source

Codon usage bias is presumably affected by tRNA selection effects in Actinidia polyploidization events. [PDF]

BMC Genomics
Zhou Y, Sheng Z, Li D, Li W, Peng Y, Song Z, Quan Z, Liu Y.   +7 more
europepmc   +1 more source

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

Cytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen, Agnieska Szyk, Antonina Roll‐Mecak   +2 more
wiley   +1 more source

Codon-Usage Bias and Genomic Architecture of 79 Psoriasis-Susceptibility Genes: Implications for Expression Efficiency and Therapeutic Targeting. [PDF]

Psoriasis (Auckl)
Jiang S, Chen L, Li J, Gao F, Yan X, Zhao Y.   +5 more
europepmc   +1 more source

Expression of mutant TIE2 p.L914F during mouse development causes embryonic lethality and defects in vascular remodeling

Developmental Dynamics, EarlyView.
Abstract Background Sporadic venous malformation (VM) is associated with the hyperactivating p.L914F mutation in TIE2, a receptor tyrosine kinase essential for vascular development. This mutation is not found in hereditary VM, suggesting incompatibility with life when expressed during early vascular development.
Lindsay J. Bischoff, Sandra Schrenk, Kara Soroko, Chhiring Sherpa, Ashok Arasu, Damien Reynaud, Elisa Boscolo   +6 more
wiley   +1 more source

Codon usage bias analysis of the <i>WRKY</i> gene family in <i>Musa acuminata</i>. [PDF]

Front Genet
Sun J, Zhang J, Zhang J, Ferguson BJ, Chen A.   +4 more
europepmc   +1 more source

Mitochondrial codon usage bias and novel phylogenetic insights: implications for taxonomic reevaluation of seven Xylotini species (Diptera, Syrphidae, Eristalinae). [PDF]

BMC Genomics
Ji Y, Li H, Yan W, Liao C.
europepmc   +1 more source

RSCUcaller: an R package for analyzing differences in relative synonymous codon usage (RSCU). [PDF]

BMC Bioinformatics
Maździarz M, Zając S, Paukszto Ł, Sawicki J.   +3 more
europepmc   +1 more source