Results 251 to 260 of about 95,149 (294)
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Codon Usage

1993
Abstract In most genes in most species, alternative synonymous codons are not used in equal frequencies (Aota et al. 1988)—Drosophila is no exception (Ashburner et al. 1984; O’Connell and Rosbash 1984; Shields et al. 1988). In Table 37.1 we present the total codon usage for 438 D. melanogaster genes.
Paul M Sharp, Andrew T Lloyd
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Preferential codon usage in genes

Gene, 1981
We present a method which permits comparison of the preferential use of degenerate codons within any gene. The method makes use of the triplet frequencies in the noncoding frames to assess whether a preference is specific to the reading frame. Preference is given a statistical meaning by use of the analysis of variance coupled to Duncan's multiple ...
S, Wain-Hobson   +3 more
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Codon usage in streptococci

Journal of Basic Microbiology, 1986
AbstractCodon usage was analysed for 14 streptococcal genes or significant open reading frames and found to be different from that in Escherichia coli and Bacillus subtilis. In particular, the preferred use of WWT codons over WWC was inconsistent with the rule of optimal codon‐anticodon interaction energy.
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Codon usage and genome composition

Journal of Molecular Evolution, 1985
The GC levels of codon third positions from 49 genomes covering a wide phylogenetic range are linearly correlated with the GC levels of the corresponding genomes. Three different relationships have been found: one for prokaryotes and viruses, one for lower eukaryotes, and one for vertebrates. All points not fitting the first relationship can be brought
G, Bernardi, G, Bernardi
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Codon usage in Plasmodium falciparum

Molecular and Biochemical Parasitology, 1988
The codon frequencies used in 7874 codons from 17 sequences of Plasmodium falciparum have been examined. The frequency distribution is markedly biased. A and C occur with similar frequency in all positions but G is predominantly in the first base and T is predominantly in the last position.
A, Saul, D, Battistutta
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Codon Usage Bias: An Endless Tale

Journal of Molecular Evolution, 2021
Since the genetic code is degenerate, several codons are translated to the same amino acid. Although these triplets were historically considered to be "synonymous" and therefore expected to be used at rather equal frequencies in all genomes, we now know that this is not the case. Indeed, since several coding sequences were obtained in the late '70s and
Andrés Iriarte   +2 more
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Codon usage and genome evolution

Current Opinion in Genetics & Development, 1994
The rates and patterns of evolution at silent sites in codons reveal much about the basic features of molecular evolution. Recent increases in the amount of sequence data available for various species and more precise knowledge of the chromosomal locations of those sequences, coming in particular from genome projects, reveal that some features of ...
P M, Sharp, G, Matassi
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Codon usage in Entamoeba histolytica

International Journal for Parasitology, 1992
The codon usage of 10 E. histolytica genes comprising 4455 codons was analysed. The codon usage revealed an extremely biased use of synonymous codons with a preference for NNU (44%) and NNA (41.4%) codons. Codons CGG (arg), AGG (arg) and CCG (pro) were absent in the E. histolytica genes examined. The codon usage of E.
S, Char, M J, Farthing
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Codon usage

1995
Abstract It should be safe to assume that two synonymous codons in a 2-codon set, or four in a family box, are used evenly. However, there are almost no such examples. Synonymous codon usage is not ‘symmetrical’. It is more or less, and sometimes extremely, uneven in any gene in a single species.
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Codon usage and intragenic position

Journal of Theoretical Biology, 1988
Data on codon usage bias in E. coli are re-examined with respect to intragenic position. The bias is less extreme near the beginning than in the rest of the gene, particularly in highly expressed genes. This is contrary to the previous finding that there is a linear decline in codon usage bias with position along weakly expressed genes but little or no
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