Results 11 to 20 of about 36,066 (191)
SARS-CoV-2 Codon Usage Bias Downregulates Host Expressed Genes With Similar Codon Usage [PDF]
Frontiers in Cell and Developmental Biology, 2020 Severe acute respiratory syndrome has spread quickly throughout the world and was declared a pandemic by the World Health Organization (WHO). The pathogenic agent is a new coronavirus (SARS-CoV-2) that infects pulmonary cells with great effectiveness. In
Andres Mariano Alonso +3 more
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Programmed ribosomal frameshifting and codon usage bias [PDF]
, 2018 Experimental evidence shows that synonymous mutations can have important consequences on genetic fitness. Many organisms display codon usage bias (CUB), where synonymous codons that are translated into the same amino acid appear with distinct frequency ...
Anisimova, Maria +2 more
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Molecular Biology Reports, 2021 Codon usage bias is the preferential or non-random use of synonymous codons, a ubiquitous phenomenon observed in bacteria, plants and animals. Different species have consistent and characteristic codon biases. Codon bias varies not only with species, family or group within kingdom, but also between the genes within an organism.
Sujatha Thankeswaran Parvathy +2 more
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Codon usage bias in radioresistant bacteria [PDF]
Gene, 2020 AbstractThe relationship between patterns of codon usage bias (CUB), the preferential usage of synonimous nucleotide triplets encoding the same amino acid, and radioresistance was investigated int he genomes of 16 taxonomically distinct radioresistant prokaryotic organisms and in a control set of 11 non-radioresistant bacteria.
Dilucca M. +3 more
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Analysis of codon usage pattern in Lonicera × heckrottii ‘Gold Flame’ based on chloroplast genome
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 2022 Codon usage bias (CUB) was a unique feature of the genome, and revealing chloroplast genome codon usage bias can provide useful information for the evolution of plant species.
Jiaqiang ZHANG +3 more
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Causes and implications of codon usage bias in RNA viruses. [PDF]
PLoS ONE, 2013 Choice of synonymous codons depends on nucleotide/dinucleotide composition of the genome (termed mutational pressure) and relative abundance of tRNAs in a cell (translational pressure).
Ilya S Belalov, Alexander N Lukashev
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Codon Usage of Hepatitis E Viruses: A Comprehensive Analysis
Frontiers in Microbiology, 2022 Hepatitis E virus (HEV) is an emerging zoonotic pathogen with multiple species and genotypes, which may be classified into human, animal, and zoonotic HEV. Codon usage bias of HEV remained unclear.
Bingzhe Li +5 more
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Ribo-seq enlightens codon usage bias [PDF]
DNA Research, 2017 Codon usage is biased between lowly and highly expressed genes in a genome-specific manner. This universal bias has been well assessed in some unicellular species, but remains problematic to assess in more complex species. We propose a new method to compute codon usage bias based on genome wide translational data. A new technique based on sequencing of
Paulet, Damien +2 more
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Quantifying Position-Dependent Codon Usage Bias [PDF]
Molecular Biology and Evolution, 2014 Although the mapping of codon to amino acid is conserved across nearly all species, the frequency at which synonymous codons are used varies both between organisms and between genes from the same organism. This variation affects diverse cellular processes including protein expression, regulation, and folding. Here, we mathematically model an additional
Hockenberry, Adam J. +3 more
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Distinct responses to rare codons in select Drosophila tissues
eLife, 2022 Codon usage bias has long been appreciated to influence protein production. Yet, relatively few studies have analyzed the impacts of codon usage on tissue-specific mRNA and protein expression.
Scott R Allen +8 more
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