Results 21 to 30 of about 5,761 (165)
Biomedicines, 2021 Photodynamic therapy (PDT) is an anticancer therapeutic modality with remarkable advantages over more conventional approaches. However, PDT is greatly limited by its dependence on external light sources.
Carla M. Magalhães +7 more
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Biomedicines, 2021 Zebrafish embryos and larvae have emerged as an excellent model in cardiovascular research and are amenable to live imaging with genetically encoded biosensors to study cardiac cell behaviours, including calcium dynamics. To monitor calcium ion levels in
Manuel Vicente +7 more
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Life, 2023 Luciferases from copepods Metridia longa and Gaussia princeps are successfully used as bioluminescent reporters for in vivo and in vitro assays. Here, we report the minimal sequence of copepod luciferases required for bioluminescence activity that was ...
Svetlana V. Markova +3 more
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Creation of Artificial Luciferase 60s from Sequential Insights and Their Applications to Bioassays
Sensors, 2023 In this study, a series of new artificial luciferases (ALucs) was created using sequential insights on missing peptide blocks, which were revealed using the alignment of existing ALuc sequences.
Sung-Bae Kim +3 more
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PLoS ONE, 2022 Native Oplophorus luciferase (OpLase) and its catalytic 19 kDa protein (wild KAZ) show highest luminescence activity with coelenterazine (CTZ) among CTZ analogs.
Satoshi Inouye +7 more
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Red-Shifted Aequorin Variants Incorporating Non-Canonical Amino Acids: Applications in In Vivo Imaging. [PDF]
PLoS ONE, 2016 The increased importance of in vivo diagnostics has posed new demands for imaging technologies. In that regard, there is a need for imaging molecules capable of expanding the applications of current state-of-the-art imaging in vivo diagnostics.
Kristen M Grinstead +7 more
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Luciferin production and luciferase transcription in the bioluminescent copepod Metridia lucens [PDF]
PeerJ, 2018 Bioluminescent copepods are often the most abundant marine zooplankton and play critical roles in oceanic food webs. Metridia copepods exhibit particularly bright bioluminescence, and the molecular basis of their light production has just recently begun ...
Michael Tessler +7 more
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BBA Advances, 2023 Gaussia luciferase (GLuc 18.2kDa; 168 residues) is a marine copepod luciferase that emits a bright blue light when oxidizing coelenterazine (CTZ). It is a helical protein where two homologous sequential repeats form two anti-parallel bundles, each made ...
Kyoko Takatsu +5 more
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Chemiluminescence Imaging of Superoxide Anion Detects Beta-Cell Function and Mass. [PDF]
PLoS ONE, 2016 Superoxide anion is produced during normal cellular respiration and plays key roles in cellular physiology with its dysregulation being associated with a variety of diseases.
Laura L Bronsart +2 more
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Bioluminescence in an Undescribed Species of Carnivorous Sponge (Cladorhizidae) From the Deep Sea
Frontiers in Marine Science, 2020 One dominant ecological trait in the dimly-lit deep-sea is the ability of organisms to emit bioluminescence. Despite its many ecological roles in deep-sea ecosystems, the presence of inherent bioluminescence in marine sponges has been debated for more ...
Séverine Martini +5 more
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