Coelenterazine sulfotransferase from Renilla muelleri.
PLoS ONE, 2022 The luciferin sulfokinase (coelenterazine sulfotransferase) of Renilla was previously reported to activate the storage form, luciferyl sulfate (coelenterazine sulfate) to luciferin (coelenterazine), the substrate for the luciferase bioluminescence ...
George Tzertzinis +7 more
doaj +4 more sources
Evidence for de novo Biosynthesis of the Luminous Substrate Coelenterazine in Ctenophores
iScience, 2020 Summary: Coelenterazine is a key substrate involved in marine bioluminescence which is used for light-production by at least nine phyla. Some luminous animals, such as the hydromedusa Aequorea, lack the ability to produce coelenterazine endogenously and ...
Manabu Bessho-Uehara +5 more
doaj +3 more sources
PLoS ONE, 2021 The Ca2+-binding photoprotein aequorin is a complex of apoAequorin (apoprotein) and (S)-2-peroxycoelenterazine. Aequorin can be regenerated by the incubation of apoAequorin with coelenterazine and molecular oxygen (O2).
Satoshi Inouye +5 more
doaj +3 more sources
Development of a Coelenterazine Derivative with Enhanced Superoxide Anion-Triggered Chemiluminescence in Aqueous Solution [PDF]
Chemosensors, 2022 Superoxide anion is a reactive oxygen species (ROS) of biological interest. More specifically, it plays a role in intra- and intercellular signaling, besides being associated with conditions such as inflammation and cancer.
José Pedro Silva +3 more
doaj +3 more sources
Theoretical Study on the Formation and Decomposition Mechanisms of Coelenterazine Dioxetanone.
The Journal of Physical Chemistry A, 2023 Bioluminescence has been drawing broad attention due to its high signal-to-noise ratio and high bioluminescence quantum yields, which has been widely applied in the fields of biomedicine, bioanalysis, and so on.
Jin-Mei Xie +6 more
semanticscholar +4 more sources
Investigation of the Superoxide Anion-Triggered Chemiluminescence of Coelenterazine Analogs [PDF]
Applied Sciences, 2023 Reactive oxygen species (ROS), including superoxide anion, are involved in regulating various signaling pathways and are also responsible for oxidative stress. Sensing superoxide anion is of particular importance due to its biological significance.
El Hadi Erbiai +3 more
doaj +2 more sources
Coelenterazine Indicators for the Specific Imaging of Human and Bovine Serum Albumins
Sensors, 2023 Albumin assays in serum are important for the prognostic assessment of many life-threatening diseases, such as heart failure, liver disease, malnutrition, inflammatory bowel disease, infections, and kidney disease. In this study, synthetic coelenterazine
Sung-Bae Kim +4 more
doaj +2 more sources
Theoretical Study of the Thermolysis Reaction and Chemiexcitation of Coelenterazine Dioxetanes [PDF]
Journal of Physical Chemistry A, 2022 Coelenterazine and other imidazopyrazinones are important bioluminescent substrates widespread in marine species and can be found in eight phyla of luminescent organisms.
Carla M. Magalhães +2 more
semanticscholar +3 more sources
Occurrence of Isopenicillin-N-Synthase Homologs in Bioluminescent Ctenophores and Implications for Coelenterazine Biosynthesis. [PDF]
PLoS ONE, 2015 The biosynthesis of the luciferin coelenterazine has remained a mystery for decades. While not all organisms that use coelenterazine appear to make it themselves, it is thought that ctenophores are a likely producer.
Warren R Francis +4 more
doaj +2 more sources
Biomedicines, 2021 Photodynamic therapy (PDT) is an anticancer therapeutic modality with remarkable advantages over more conventional approaches. However, PDT is greatly limited by its dependence on external light sources.
Carla M. Magalhães +7 more
doaj +2 more sources